I have wondered this for a long time. I was not able to find much using the search function. Does anyone know or have any info on why things like 2-ce and 3-meo-pce have onsets that take so much longer to come up than others in their same class? Is there some metabolism needed to make them active? Perhaps it's just absorbed by the brain differently? Eth- lad does not seem to be delayed. I know ethyl psychs vary widely and it may not apply to all ethyl psychs but I would love to get some understanding as they tend to be my favorites of all that I have tried.