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Why are drugs no longer doing anything?

In an alternate universe, this thread is 2 posts long:

(Post 1) I'm pretty sure my mom died of Huntington's. I'm starting to feel odd.

(Post 2) Get yourself tested.


Then again, I'm the last one that should be talking about pointless threads.
 
seep said:
In an alternate universe, this thread is 2 posts long:

(Post 1) I'm pretty sure my mom died of Huntington's. I'm starting to feel odd.

(Post 2) Get yourself tested.


Then again, I'm the last one that should be talking about pointless threads.
Click to expand...

Well no, not quite. This thread has gone poorly so far, ill try and be more helpful then other posters.

First, the 50% chance you quote is correct assuming your mother had huntingtons, but you will see NO affects from this illness until at the very earliest your early 40s, so anything you feel now is not related to this diagnosis. Getting tested is an option if you want to know for sure about what the future will bring, but as their is nothing even resembling a cure that is a choose you should make based on how you think life would be knowing around the age you would die.

I would agree with earlier posters, clinical depression characteristic by anhedonia (loss of fun) seems the likely cause of your symptoms. The feelings of loss and hopelessness along with general anger at oneself and the world are pretty typical, there is not necessarily a reason one feels depressed, to our knowledge clinical depression is caused by neurotransmitter imbalances that could affect someone even if their life has not had a recent dramatic change.

I would seek the help of a medical professional, as a psyc major in college I can tell you that modern treatment for depression (clinical sessions rather then SSRIs) are very effective especially in the under 26 category.

Best of luck, feel better.
 
On the other hand, if his mother didn't have Huntington's, there's zero chance he will. He has said his maternal grandfather had Huntington's and that his mother's death resembled a Huntington's death, but that his father told him the tests done on the mother were negative for Huntington's.

He believes his father may be lying about the negative result so that he (its.euphoric) will not get scared about his own future. This is a plausible assumption. However, a highly-reliable diagnostic test for Huntington's didn't exist until 1993, so the question shifts to whether it is known for sure that the grandfather died of Huntington's. OP's glass may be a lot fuller than he thinks it is.
 
Most people think that the disease only affects you later in life... and that is what's most common.

But in less than 10% of the cases it develops before 20 years old... It is possible, and it's called juvenile hd. You can start feeling affects anytime in life actually.

I never have talked to anyone who understands what I mean, when I explain how I feel. They just think there's something secretly wrong in my life that is making me sad or they just don't get it when I try to explain what's going on.


And I tried lexapro. The first time, was during the summer, and it didn't really do anything.
Recently I tried it again and it made me feel so horrible. It felt like my mind was just more out of it than usual and I could not stop yawning. It was actually kinda painful.
 
seep said:
On the other hand, if his mother didn't have Huntington's, there's zero chance he will. He has said his maternal grandfather had Huntington's and that his mother's death resembled a Huntington's death, but that his father told him the tests done on the mother were negative for Huntington's.

He believes his father may be lying about the negative result so that he (its.euphoric) will not get scared about his own future. This is a plausible assumption. However, a highly-reliable diagnostic test for Huntington's didn't exist until 1993, so the question shifts to whether it is known for sure that the grandfather died of Huntington's. OP's glass may be a lot fuller than he thinks it is.
Click to expand...

my dad also said that a few years before my mom died that they noticed plaque build up in the brain... Which is actually what happens in hd. But I don't think he remembered that he told me that
 
How is this a question for Advanced Drug Discussion??

You're obviously just depressed, and perhaps exposed to a sudden tolerance regarding effectiveness of the various substances - or perhaps you are just getting slightly older - I dunno your age - but your brain and body develop and change throughout life..

Maybe you just remember the effects of the drugs as better before, because you were happier and more content back then? Can be loads of things.

I used to be able to get insanely drunk 3 days a week and get no, or very little hangovers just a few years ago.
Now a simple weekend binge will put me out for an entire day, if I drink similiar amounts :)


But judging from your first post, you do sound somewhat depressed.
 
its.euphoric said:
my dad also said that a few years before my mom died that they noticed plaque build up in the brain... Which is actually what happens in hd. But I don't think he remembered that he told me that
Click to expand...

Apparently, since the discovery and elucidation of the gene in the 80's and 90's, it's become common for Huntington families to have a complicated set of attitudes toward predictive testing. My knee-jerk reaction was to think of it as any other horrible disease that can be confirmed or ruled out by a simple test, but the issue is a bit more convoluted. There's more going on psychologically than fear.

If it's anywhere near helpful, I'll say that as a teen an ex-girlfriend told me she had been tested for HIV and the test came back positive. This is back when AIDS was barely manageable. For like 3 months after she told me, I was freaking out badly and having visual, auditory, tactile and command hallucinations. I decompensated to like a DEFCON-1 psychotic episode and was involuntarily committed to a crisis unit. They tested me against my will, but as soon as the test came back negative for HIV I was--I was sorely disappointed. The psychosis morphed into profound depression, and it took another month for the cloud to lift. I think they finally coded me as factitious just to get rid of me (my insurance didn't reimburse for factitious disorder).

But I guess it's not irrelevant to mention that before I was tested I got into the habit of eating cafeteria furniture--a compulsion that stopped once I got the results.
 
Maybe the government is broadcasting drug interfering radio waves into all population areas. Or maybe your drugs are off.

I have noticed that street drug purity and availability are way down from say 10 years ago. And in the 1990s, there was tons of lsd and mdma to be found.

(yes, i know california still has mdma in 2010 but california never loses anything! it's all there somewhere, hidden away.)
 
seep said:
Apparently, since the discovery and elucidation of the gene in the 80's and 90's, it's become common for Huntington families to have a complicated set of attitudes toward predictive testing. My knee-jerk reaction was to think of it as any other horrible disease that can be confirmed or ruled out by a simple test, but the issue is a bit more convoluted. There's more going on psychologically than fear.

If it's anywhere near helpful, I'll say that as a teen an ex-girlfriend told me she had been tested for HIV and the test came back positive. This is back when AIDS was barely manageable. For like 3 months after she told me, I was freaking out badly and having visual, auditory, tactile and command hallucinations. I decompensated to like a DEFCON-1 psychotic episode and was involuntarily committed to a crisis unit. They tested me against my will, but as soon as the test came back negative for HIV I was--I was sorely disappointed. The psychosis morphed into profound depression, and it took another month for the cloud to lift. I think they finally coded me as factitious just to get rid of me (my insurance didn't reimburse for factitious disorder).

But I guess it's not irrelevant to mention that before I was tested I got into the habit of eating cafeteria furniture--a compulsion that stopped once I got the results.
Click to expand...

that's a cool story. And I mean, many times I've freaked out about things like I've thought I've had many diseases, but usually after a little while I find out it's something else. But I've researched so much, and just everything I look up just comes back to what I feared....

and... seep thanks for posting.
 
The more you obsess about something and "research it" etc.. the more hopeless you will feel.
I would research the fuck out of my back issues and i would get crazy depressed which led to my drug use. Now, i know whats up, but i dont go making it any harder on myself by looking at what has happened to others and instead focus on fixing other things in my life so that overall, i'm very happy. Your brain is a powerful tool; if you tell it you've got this or that everyday for a long as time, chances are your going to develop symtoms. My advice: chill the fuck out and quit the drugs, find whats makes you happy, get into shape, form relationships, get a fucking job for christ sake and take your mind off of something you cant do a shit fuck about so why bother? Just try and be happy instead of moping around all day, its only adding to your list of problems because instead of trying to resolve other things your just making it worse and worse.
 
@seep -

That is an incredible story. Amazing.

@ the OP -

You're 19 correct? You are a legal adult now. Your father cannot see your medical records. (I'm assuming you live in the US.)

Everything you described, particularly the blunted feeling and excessive sleep, is symptomatic of depression. That's completely understandable as well if you believe you may have Huntington's - truly a terrible disease.

So my advice is simple:

Save, scrimp, and sell whatever you have to so you can make the co-pay and go get tested for Huntington's on your own. Your dad doesn't have to know you went to get tested.

If you have the disease, then you can begin psychotherapy with a clear agenda. Shit, maybe it would be liberating just to know what is going on with you and begin working on disease management.

but even better...

If you test negative, I'm sure you will react just like Woody Allen in Hannah and Her Sisters or whatever movie it was where he thought he had a brain tumor - you'll be skipping and running and screaming and jumping and probably feel higher than if you did any drug you've come across before.

No matter what happens, good luck.
 
Hi there its.euphoric... I emailed you before I saw this thread. I've been through a very similar experience and if you want to chat, let me know. I know exactly what you are going through and would really appreciate the chance to swap war stories.
 
Hello again - I got your PM but I'm not allowed to respond because I'm a Greenlighter. If you want to PM me an email address that you use, I'll email you shortly.
 
A greenlighter is fresh, like green wood. It means they have less than a certain number of posts, maybe 50. It is a prison term. The cutoff used to be 20, but I think they changed it.
 
I have been on here for years unable to post because all my IP addresses were always blocked. Made no fucking sense. Now I get on a few days ago after the first try in probably 6 months and it lets me. So now I get to serve my prison term, as if reading posts on here for years without being able to voice my druggy opinion and dick size wasn't enough!

Drugs continue to do something when you aren't getting high, they prevent withdrawals. Stop doing all of them and you will believe me. Taper off whatever you are on, take a break, get some SSRI's or Benzo's (Klonopin for a month at max), work out, get some rest. Your brain will thank you and you will feel better if you allow yourself to.

In my opinion you are so deep into believing that you have some sort of tropical illness or gangrene of the brain that your whole salvatioin relies on you being able to convince yourself the actual truth, which is that you are not crazy or dying, but are rather a depressed drug addict that is unhappy because he cannot do more than the amount of drugs needed to just stop withdrawals.
 
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