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White Heroin

is this what christmas does do greenlighters? ugg....santa isn't bringing any coal, rock, or brown clumps of H for any of you trolls!

swybs
 
mu kappa delta hahaha i like that....and rivered aint no beef im gonna put the pass behind and move on cuz aint no need to beef with my fellow opiate/opioid lovers
 
My H hook didnt answer today. I guess I can give him christmas eve off, but tomorrow is pushing it.
 
ZZZZZ...

He even types in ebonics. I AM impressed. When your mom was watching MTV I was shooting dope kid. You and your boyfriend said that heroin cut with lidocaine was a myth. I provided a paper that said different. Not only did I say that this paper was not paticularly about lidocaine and heroin, and that it only mentioned it in its first two sentences, but I also provided two whole articles on lidocaine in heroin that you obviously did not take the time to even type in. No hyper link means it does not exist, right? Instead of watching "Boys in the Hood" for dialect lessons try and really learn something, it might even save your life.

If somebody sold you morphine and you sniffed it, you would have to sniff a shitload to feel anything. If you knew what you were talking about you would not even have raised it as a point, CUZZ. You little pisants are good for a laugh though. Man, I love little suburban ass crackers trying to front after watching Fat Albert cartoons and a copy of their mom's baby's daddy's bootlegged copy of "Barbershop" for lifestyle hints... Ulbah balbah Albah...Try living in a ghetto and maybe you won't dig it so much. Personally, I am trying to get out, not capitalizing on its supposed cache. But since you "put it on pass" I guess I' ll let this "beef" [sic] die a much needed natural death...
 
yo said suburban crackaz smh fuck outta here on the real cuzz i will smack ya white face till it turn pussy color pink dont play wit me if anybody a saltine on this bitch its you hahahaha yo recyclin 1982 motha jokes come on how you look right now? and whatchu said about the morphine...how you gon have to sniff a "shitload" when whatever dosage you sniff hit you with double effects for example if you sniff a 15mg msir pill its gon feel like 30mg so think before you type you clown ass saltine oh and aint no beef passin between us you bitch made whore i said the beef between me and rivered over dont get it mistaken...i dont fuck wit you correction dont nobody on this forum fuck wit you im jus clearin that up for ya lonley clown ass
 
From the desk of a lonely clown ass...

You a smack my white face [sic]? Right. You are black? Who cares? You still type like a retard. An inflection cannot be typed genius. There is only one reason someone would go out of their way to do that, they want to prove something. If you are black you're stupider than you sound, and you're still country as hell.

If you sniff a 15 mg morphine pill you will waste your money. There are two tiny things called bioavailability and first pass metabolism. If I cared enough I'd explain. Just because you insufflate something does not mean that you will get a better result. Case in point: methadone. Take that orally and insufflate the same dose [on a different occasion of course]. You'll see the different results.
 
Cant we all just get along? Well it doesn't look like it. But just for your knowledge southernwhatever, you are absolutely wrong about the whole sniffing morphine thing and the "controversy" over heroin being cut with lidocaine.

Since you've only been around for 6 posts (and I can't tell if you're serious or just fucking around) ill let you in on the fact that Rachamim is a very knowledgable person when it comes to opiates and a reasonable person when he's not pissed off. The corrections he made were for the purpose of harm reduction (also the purpose of this board) and not to show you up, which is how you took it.

Basically Im saying let's all just chill.. all this shit-talking is really pointless ESPECIALLY when it's with a person you'll never meet or don't know anything about.
 
Most likely.. in any case this thread should be closed cause all issues have been addressed and its only a place for more trash talking.
 
nah obviously hes not too educated when it come to opiates hahahaha first pass metabolism only takes place when you swallow morphine which is why you should insufflate it or shoot it instead to defeat this liver function
 
rachamim: I wouldn't call it a case of "moderatis." I like to see a friendly environment on the board. If it were true "moderatis" I woulda hit the report button or told someone they were violating forum rules or been a nosey prick in some other way. I guess I just hate seeing hostility when I'm in a "nod-state-of-mind."
 
Jive Talkin Know It All...

This is exactly how big mouthed people trip themselves up: First Pass Metabolism is indeed a concept related to some oral meds...That is EXACTLY why you would not insufflate [effectively] those supposed dimes of morphine...Insufflated morphine is a waste which you would know if you were half the hustler you claim to be...or should I say "hustla." You should not care about defeating the liver function as Hepatic Pass Effect refers to METABOLIZING a substance EFFECTIVELY.
 
First Pass...

Let me put in words even you can understand, Hustla [sic]: If you were holding up oral consumption against intravenous consumption than oral would lose as it is only about 40% effective on average. To insufflate it though, the only way that you could effectively do that would be if it was in hydrochloride form, not crushed up tabs or pills. Assuming that you had hcl you would be right. As it is, that is almost never the case. Most get the Contin [Sulfate] or other preps and grind them down. Let's say that your "connection" is one of those rare people that has an uninterrupted flow of morphine hcl., then you are right. Personally I think you are full of it, or just mistaken at best. The only way to tell the difference outside of the lab is to do an m.p. and with illicit samples that wouldn't mean shit anyway. All it would seem like is weak ass dope, which brings up the real reason I doubt your story. In the supposed "heroin capitol" junkies are buying a powder that only gets them 1/3rd as high? I doubt it...but if you insist...I really don't care in the end.
 
In phamacology (if I recall correctly), 1st pass clearance refers to the compound getting absorbed into the bloodstream through the stomach/intestines. In the lecture I sat on this, the example was the contrast between salicylic acid and aspirin. [Although here the driving force was almost entirely with the object of lessening salicylic acids caustic effect on the stomach lining].

When one refers to a method of drug delivery that avoids first pass clearance we normally perceive this as some sort of advantage. This is especially true with delicate molecules such as morphine. If the ether linkage in morphine is destroyed (which occurs readily by the low pH environment in the stomach), the corresponding compound is only feebly active. [Although in crazy examples, such as PPOM and the like, this may actually be deliberate in an attempt to increase the compounds bioavailability. However crazy stuff aside it is best to keep the ether linkage in-tact].

With amphetamine-like devils a completely different rationale is used. In this case the motivation is completely kinetic in origin:- IV use gives a quicker onset and shorter duration of action. Hence it is more addictive according to the drug addiction experts. They argue that the euphoric rush and edgy crash leaves the user craving more. Hence due to the increased chance of repeated administration, this method of drug delivery is considered more addictive.

Back to thread title: White Heroin => I read an review on the web compiled by DEA informants. Here they claimed that the corresponding fent analog made by employing acetic anhydride in the last step of the synthesis, has a differing phamacological profile. They claimed that although 10-fold less potent it had a duration of action that is ~twice that of regular fent. [I would offer a reference for this but the website that I got this from is currently down].

That sounds cool though, doesnt it? 10X weaker means a greatly reduced risk of a potentially lethal OD. Since it lasts twice as long there less demand for redosing. Almost as though there has been a form of compensation provided for the 10-fold drop in potency. Assuming the product was cut 9/1 and that sniffing it meant that it is no less active than IV administration, that would mean sniffing only 10mg of powder (!) If one felt that they needed more euphoria, they could always upgrade this to the corresponding alpha-methyl analogue (in accordance with negro's earlier comments regarding AMF and euphoria) White heroin indeed....[sigh]
 
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