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Whats the best drug combo of All time ?

Guys I found the best drug combo ever!
Its:
[subjective drug at subjective dosage] +
[subjective drug at subjective dosage] +
[subjective drug at subjective dosage]
I figured out the secret guys!

JK
I enjoy reading all your fun combos, but its important to remember the degree of subjectivity, difference in tolerance and preferences when it comes to drug combinations. So be careful when trying out things suggested in this thread. I myself am probably guilty for suggesting some outlandish or pure preference combos lol
The amount of reckless shit I'd love to go off about, but I just never want people to do is pretty large. One that I will talk about since it's virtually inaccessible nowadays and is likely never coming back though was combining ~4.8mg of sublingual 25C-NBOMe with an MDA pressie that was allegedly 125mg that I bought off a Billy Strings lot. That shit was fascinating, one of the most profoundly hyperthermic experiences of my life and I already run hot, thank fuck it was winter in Maine. To this day, I have not felt euphoria like that and I don't know if I'm trying to dude, it was a lot. A recent experience that was similar was oxycodone, methamphetamine, carisoprodol (Soma), etizolam, THC-B/THC in a box mod, and an estimated 225ug of LSD. that was similar in euphoria but it was almost certainly safer and less toxic.
 
68 year old guy who's done it all in my younger days thrugh the 60s and 70s. Now, I enjoy my oxy with kpins and a beer or two. I started taking oxy and valium many years ago for pain and health issues ( beat up from ice hockey days) but soon found oxy and val was a nice mix with a couple brews. I later changed to klonopins as I long their longer action in the bloodstream. I would say I'm an addict as I've been on them a long time, even though they are lower doses than most people here take. I'm currently trying to wean off of them as the DEA continues to scare doctors from writing scrips for opioids and benzos. It's just a matter of time before they get to my doc and I get that dreaded appt where doc says she has to pull my scripts. I do not want to go cold turkey so I'd rather wean off slowly now while I still have the chance.
 
68 year old guy who's done it all in my younger days thrugh the 60s and 70s. Now, I enjoy my oxy with kpins and a beer or two. I started taking oxy and valium many years ago for pain and health issues ( beat up from ice hockey days) but soon found oxy and val was a nice mix with a couple brews. I later changed to klonopins as I long their longer action in the bloodstream. I would say I'm an addict as I've been on them a long time, even though they are lower doses than most people here take. I'm currently trying to wean off of them as the DEA continues to scare doctors from writing scrips for opioids and benzos. It's just a matter of time before they get to my doc and I get that dreaded appt where doc says she has to pull my scripts. I do not want to go cold turkey so I'd rather wean off slowly now while I still have the chance.
Its smart trying to taper down. I have always had insomnia. I take Seroquell and prescription Ambien. I also take half a Xanax, sometimes I have to take another quarter. I am trying to quit the Xanax, but then I just lie there until the sun comes up. I don't get high off them at all, I just want to sleep.

I actually wish I had a little bit of narcolepsy so that I would sleep easier.
 
While I don't recommend mixing these together without prior experience with one of the two substances, mixing a heavy meth binge with a dose of acid is in a class by itself. First time I tried LSD I was on day three and the experience was life altering.
Damn, this sounds absolutely terrifying. I've experienced some pretty intense meth induced phycosis, like way gone.

And have experienced some pretty intense LSD hallucinations.

Man mixing the two seems like a recipe for disaster.
 
An interesting one to throw in here is intranasal buspirone, DPT and methamphetamine to emulate a methier version of the general vibe of 5-MeO-DiPT. Is it safe? No clue. It is however the absolute horniest combination of drugs I've ever consumed, and I am often in pursuit of exotic and well refined combinations of drugs for pro-sexual effects since I'm functionally totally asexual at my baseline and that's not great for sustaining relationships.
 
oh god there’s too many to choose from. in terms of psychedelics- LSD + MDMA + K + DMT + Nitrous is heavenly. candy flipping, doing a few lines of K, smoking DMT and then taking a balloon right as you blast off will have you reach nirvana, tho you won’t remember any of it.

otherwise valium + vicodin + a couple drinks + a lot of coke makes for a very euphoric and very dangerous combo that you also won’t remember and that i cannot recommend. it’s much more of a downer combo than upper, but the coke helps keep you up and focused enough to function while letting you stay nice and sedated. if ya take the right amount and keep the valium and booze doses low it keeps you from blacking out at hard, tho once all the drugs are in your system the compulsion to take more gets a lot harder to fight against. definitely not a combo that i recommend or is particularly safe, but in my harder partying days i did it a handful of times.
 
otherwise valium + vicodin + a couple drinks + a lot of coke makes for a very euphoric and very dangerous combo that you also won’t remember and that i cannot recommend. it’s much more of a downer combo than upper, but the coke helps keep you up and focused enough to function while letting you stay nice and sedated. if ya take the right amount and keep the valium and booze doses low it keeps you from blacking out at hard, tho once all the drugs are in your system the compulsion to take more gets a lot harder to fight against. definitely not a combo that i recommend or is particularly safe, but in my harder partying days i did it a handful of times.
Soma, 7-Hydroxymitragynine, etizolam and 4-Fluoromethylphenidate was a RC variant of this combo that I used to play with which induced some absolutely fucking incomparable euphoria but it would also occasionally have me responding to mild acts of aggression with amounts of force that were completely unwarranted. I was in a pretty dangerous neighborhood at that time, but when people acted a fool this exact combo would turn me into the thing that goes bump in the night for some reason.
 
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