The origins of tusi was because back in the late 2000's. Colombian elites were introduced to true 2C-B by an underground psychedelic chemist named alejo. Street level vendors eventually heard about this, and as 2C-B is actually quite rare in colombia, they made a knock off named tusi/tussi which is almost always Ketamine with some synthetic stimulant(s) such as MDMA or even now a days cathinones. I've tested several batches of tussi at the testing laboratory, and in the united states at least, it has always been either just ketamine, or ketamine with a dash of MDMA (to fool reagent tests). Because of this strange phenomenon, true 2C-B is almost always more expensive in the US in predominantly latin areas such as Miami.
The rising popularity of a synthetic drug in Colombias most elite club scene is indicative of a global trend, in which demand for heroin and cocaine is dropping and the use of manufactured stimulants is going up.
insightcrime.org
Fun story. When I was living in Ecuador I met these low level street cocaine dealers who were from Venezuela. Well one night after driving with some of them to pick up some cocaine, i offered them 2C-B. Were Venezuelans we've tried 2C before we've tried everything they say to me. I explained to them no this was different. They looked at me like some dumb gringo. I convinced one them to try a small amount. He looked pretty dubious about the tiny bit of powder him I was offereing him but he went for it. We walk into a salsa club as a group. Oh in about 40 minutes, that one kid was basically stripping off all his clothes on the dance floor in a very ecstatic way. The others seeing this, said i guess we'll try some. That night was wild. But even crazier is whoever their higher up was heard about it and me and also had me share a small bit with him, so I moved up the chain. When I had met these kids, they were selling me maybe a ball of really cut cocaine for $50. By the time I left Ecuador, they were selling me 10-15g of fucking pure cocaine for the same price. That actually got me into trouble cuz 2 nights before flying home, I decided to grab a little. They knew I was leaving so they really hooked me up that time. I was like shit. I've got 2 days and 15g of fishscale. Even with my habit at that time, I was worried it would kill me. So my last night I decided to go the party area in Quito where I met some folks and shared my really good cocaine (as a gringo). They ended up drugging me with scopalamine, and I woke up about 40 miles away in one of the sketchiest areas I've ever been in. No cocaine, no debit card, no cash. Thank god I'd left maybe $50 back at my hotel. I ran past the bazuka (crack) heads to the sound of traffic and a busy road. I flagged down a taxi driver, told him I'd give him $30 to get me back to downtown quito. which he did happily cuz that was probably a $15 ride. Made it back to hotel, took the last of my cash and hired a taxi to get me to the airport. Maybe it back to Miami during a hurricane no less, with less than 50 cents on me. Had a friend buy me a ticket out of Miami and the scooped me in indianapolis from Illinois, made it to illinois and my bank and I was fine after that. Sorry to ramble, can't make this shit up tho.