This is essentially true of all drugs. Regarding mushrooms though, that's a drug that could theoretically be systematically hunted down and destroyed, placing it first as an endangered species and then with enough effort, it could be eradicated entirely from the planet the same way various plants and animals have gone extinct. Extremely unlikely, but technically possible. Psilocin, et al. would still be known and possible to synthesize but the natural species of mushrooms could be eradicated.
That's probably accurate, although GHB from GBL is easy. DMT extraction from certain root barks is also fairly easy. Meth from ephedrine is easy if you have the precursor and reagents needed and know what you're doing.
I love how some people think they're "cooking ketamine" when they dehydrate a saline solution containing ketamine.hcl. That doesn't count. Also converting coke to crack is easy, though it doesn't really count either.
While I take your meaning – you don't need special grow lights nor exposure to sunlight for specific hours each day to grow shrooms – there are some light requirements. The mycelium should be grown in the dark, but to initiate pinning, you need light to trigger that mycelium. Basic indoor lights that any room has is sufficient though. Also, indeed gas exchange is necessary to grow shrooms and adequate ventilation along with adequate humidity/moisture levels are needed as well. It smells faintly of wet perlite, but it doesn't reek the way cannabis does. The difficulty is in maintaining sterility, which usually isn't that difficult once you know what you're doing.
You mean other than the fact you can't feel the effects of MDMA and the effects of many psychedelics are partially suppressed & dulled if not muted by the Zoloft? Or does that not happen with you? Many people experience weight gain and sexual dysfunction along with a drop in libido even after months of being on it. What about atypical antidepressants? Given the severity of your condition, you may not be inclined to experiment here, and I wouldn't blame you if that were the case. I'm just not a fan of what SSRIs sometimes do to certain people, but what does it matter what I think? If it works for you, it works.
Do you ever think about trying a different medication, or you're good with Zoloft so why bother?