Well it seems to be your week you MehDMA believers. Check out this recent analysis on DrugsData showing more byproduct than MDMA present.
[QUOTE="G_Chem, post: 15524454, me...www.drugsdata.org/view.php?id=12892
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Edit- It appears this press has been around for a minute.
DrugsData (EcstasyData) lab testing result
www.drugsdata.org
-GC
This checks out. M-Alpha-HMCA is a byproduct of MDMA synthesis when unconverted PMK-glycidate is present. This is very interesting and lends much credence to the hypothesis that the introduction of a new precursor marked the introduction of heavily contaminated MDMA in several markets which may indeed account for experiences of mehDMA. Nice find, G! Thanks for sharing this
G_Chem you are simply a legend. Thank you.
I can’t help but give a wry smile. I think I’ve said this about 20 times at least since Le Junk started the first version of this thread. And without fail certain people would continually pipe up and provide a chemistry lecture on how glycidate is easily turned to MDP2P and everything ought be sweet from there and not deal with the reality of what is surely happening.
Of course glycidate could make perfect ketone which could make perfect MDMA if it was treated right and each product purified properly as one goes. But is that happening? Most of the time probably not but who the hell really knows. Take a look at the PMK-glycidate molecule. It is going to be as reactive as fuck with who knows what side reactions and potential products being created.
I’m sorry but in the wrong hands or in a rushed, corner cutting, profit driven synthesis of MDMA, this bitch below is going to create some serious problems. And what’s more this is just one of the MANY different PMK glycidates available, all of which will create their own list of potential unwanted and exotic side guests in anyone’s reaction.
And what of this potential glycidate to amine one pot synth. If that is happening or something even close to it is happening, then you are going to get achiral products, you are going to get molecules like the one discussed above (goodness knows what this might do but it certainly isn’t MDMA) and I still believe you might get some large dimer type molecules which may well have a structure approaching indigo’s potentially potent DAT and SERT transporter blocking molecules - or maybe it’s all three - whatever the case it’s the perfect storm and I don’t think anyone really knows what impurities/unintended products might be created from such precursors, especially when you are using a bigger molecule and breaking it up to get to what you want. And in breaking apart that structure, what happens to the other bit that you have removed to get the ketone and no doubt don’t want and what do you do with the portion of your reaction that contains glycidate molecule that’s broken apart in completely the wrong way. It might be in the minority but it’s there. What is going to be created when these unwanted “precursors” get put through the exact same process as the PMK part of the mixture undergoes to make mdma.
I’ve deliberately written the above fairly chaotically and haphazardly because that is where we are with this precursor and others like it and we really need research scientists to analyse the impurity profiles of mdma samples produced from these precursors (which are by far the most common now) like they have done for the older methods for two decades plus. It will eventually happen I have no doubt. When I have no idea. What they will find I have even less of an idea, but as I’ve said over and over and over again, the answer or answers to this entire issue lies here.
And if you are still not sure about this, check out this Australian illicit drug report -
www.acic.gov.au
Click amphetamine type stims section and go to page 8.
We have talked about this before, and the clear shift from borohydride reductive amination to platinum hydrogenation. But what of this other method or methods - reductive amination “unclassified route” or routes was almost 50% of all seizures. Unhelpful but what is it. Is this in reference to the mythical “one-pot” reductive amination of PMK-glycidate to MDMA or is it something else. We need to know. Most frustratingly, since 2016, the profiling of MDMA seizures stopped so I cannot give you similar data for last five years. What might it tell us? What trends would be apparent? Which government laboratories have these answers?
If only the mighty Sasha Shulgin was still alive (may he RIP), because I for one would cross continents to hear his theories and views regarding this Meh-ss.
