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What drugs have you ruined?

I must say that I have far over used and abused cigarettes. I hate the smell of 'em, the look of 'em - everything about them is so gross now. Before I could smoke nearly a pack a day, smoke inside the house and all - now I hate that shit.

Benzos are another - they just don't work for me at all anymore.
 
Adderall/Vyvanse/All similiar stimulants:used them a good bit back in the beginning of Highschool, like twice a week and i was prescribed, at different times, and now i HATE the stimulant high. i cant even take 15mgs of adderall without staying up literally all night and having dysphoria. although i do take about 10mg's to help me with studies for college. but i always take opiates or benzos right after im done with schoolwork on adderall. i hate the high i get from it. absolutely hate it now. i have no idea why i liked it when i was younger.
 
ambien- I only used it about 3 or 4 times and it was great the first couple of times, but my last venture in ambienland was horrible. I remember popping 4 10mg pills and a whole 5 minutes more of that night. When I woke up my room was in complete disaray and when I looked at my ambien bottle it was empty. I must have taken the other 6 pills in there in my slumber. Now i'm totally scared to take ambien.
I also found out a few nights after that I had posted about 10 messages on BL expressing my joy and hallucinations haha.
 
Be careful about mixing SSRIs and MDMA - you risk Serotonin Syndrome. Play safe! :)
 
Weed. Like a lot of people, I was a daily weed smoker for years and then it turned on me. Now I get horrible anxiety, paranoia and rapid heart rate from it to the point I avoid it altogether. Would love to know the scientific/medical reason behind this, as I've heard sooo many others say the same thing.

Ha! I thought it was just me! I'm exactly the same... smoked hash / weed for bloody years and then suddenly got exactly the symptoms you describe. I quit the stuff in my thirties and always regret it when I try any lately.
 
Weed, smoked so much synthetics it barely has any effect any longer.
MDMA, used to give almost no effect at all after doing lots of it and 4-MMC -> maybe works better now after years of break.
Opiates -> tolerance kind of ruins it here, so expensive, also get addicted so easily these days

:/
 
Well, if I'm to really be honest, than I would have to say heroin. For about a month there I just wasn't getting high anymore, but then I switched connects so I got some of the magic back. But opiates are ever going to be the same unless I take a long break.

For some reason though benzodiazepines continue to work for me, even with a habit. The thing is that I actually have a lot more will power with them than the latter. I'm prescribed 1mg/day, but will often take 3-4mg/day (of clonazepam) and then not take any until I cannot stand it (which is around the 72 hour mark). Also, strangely enough, if I decide to continue to use benzo's, and have been taking 3-4mg of clonazepam a day, if I switch to alprazolam I can get off on half as much which I find strange as they're pretty much equipotent. Granted, clonazepam has a much longer duration of action, but the onset is pretty similar to Xanax IME if taken sublingually, and if its been 3 days, 1mg of clonazepam feels stronger than 1mg of Xanax. Doesn't make much sense.
 
First weed- was just making me really antisocial/ paranoid/ anxious.
Then mdma- lost the euphoria, can't enjoy it anymore.
Now benzos.
 
In reference to the thread that was merged here on page 2: Yes, I got bored of heroin and now I am on methadone. But it wasnt until i forced myself on done for a drug test that i realized how much i have fallen out of love with it. Ive used a couple of times since being on done, old habits are hard to break, but i feel guilt after using and dont really enjoy it. Kind of like a "this is it?" kind of feeling. Im glad my feelings towards heroin are evolving. This is a unexpected, but welcome, change of heart.

Anyway, drugs ive ruined by over using are iv coke and meth. Never again.
 
coke for sure

I cannot do it anymore without fiending like a mofo and getting ridiculously drunk. Like blacking out and making extremely risky and poor decisions.
 
Well, if I'm to really be honest, than I would have to say heroin. For about a month there I just wasn't getting high anymore, but then I switched connects so I got some of the magic back. But opiates are ever going to be the same unless I take a long break.

For some reason though benzodiazepines continue to work for me, even with a habit. The thing is that I actually have a lot more will power with them than the latter. I'm prescribed 1mg/day, but will often take 3-4mg/day (of clonazepam) and then not take any until I cannot stand it (which is around the 72 hour mark). Also, strangely enough, if I decide to continue to use benzo's, and have been taking 3-4mg of clonazepam a day, if I switch to alprazolam I can get off on half as much which I find strange as they're pretty much equipotent. Granted, clonazepam has a much longer duration of action, but the onset is pretty similar to Xanax IME if taken sublingually, and if its been 3 days, 1mg of clonazepam feels stronger than 1mg of Xanax. Doesn't make much sense.

unlike almost every other drug, benzos do not effect dopamine levels, they just effect GABA. Since there is no built in tolerance system associated with GABA as with the dopamine reward circuit or with increased opiate or cannabinoid receptors. Thus you can take the exact same dose for years and years without needing to increase it to get desired effects. hence although continued use causes physical and psychological dependence benzos are not addicting. xanax has a quicker onset but I think an equal amount of clonazepam produces a greater GABA release.
 
Weed fucked mine up. Never done really harder drugs ( okay dexamphetamines, clonazepam)
 
Valium... I used to be able to take 8-10 5mg tablets and get awesome euphoria. Now 5mg has the same effect as 50mg.

MDMA. I started that when i was 13 by the time i was 20 i needed to use a whole bunch of other stuff; coke, amphetamines etc with it to get the high i used to get when i was 13 - damn they were fun days back then though!!!

Oxycodone - my tolerance got so high i couldn't get euphoric or even noddy off any dose i tried, and i tried some pretty damn high doses!! Ended up needing benzos to help it with that one. Now i am clean i guess i may get high off a couple of 80mg tablets.

DXM - seems every time i use this i need more.
 
Etizolam - The first time I tried etis it took 5-6mgs to relax me, the last time I lost count after around 33mg. I was still functioning (managed to not get arrested when pulled over), and on other sedatives, which is scarey. Obviously blacked out.

Speed or Cocaine - Both are dead to me now w/o a strong Opiate to ease the extreme anxiety they give me. Still miss the rush though.

Hydrocodone - I don't think anything short of a CWE would get me a hydrocodone high again. That or years of abstinence, which is highly unlikely. I miss the Norcos like no other.

OxyCodone - First time I tried it 20mg knocked me on my ass for around 18 hours. Last time I tried it I took 200mgs and barely got well.

Diazepam - You were my favorite. Now I need at least 80mgs to take the edge off.
 
Heroin. Can't do it without ruining my life.

Dxm... Used to love Dxm did it every night. Ended up in the hospital thinking I woke up from a life long coma... And I've been dreaming for the last 19 years... Might give it another try soon though I miss Dxm land and my friends there
 
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