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Miscellaneous What are your favorite psychedelics?

Yeah you kinda spooked me for a sec but then I was like wait, I've taken more 2C-D than anyone I know at least. Not that one would always be able to notice self induced brain damage.
 
Let's also not forget that some things which are meant not to cross the BBB might do it anyways. There is a link between PD and exposure to paraquat or similar pestidices, these are already in the charged aromatic state. But once in the brain that same BBB which is meant to protect also traps molecules within it to wreak all sorts of redox cycling havoc.

PD is a mixture of internal and external factors leading to the continued degradation of the substantia nigra, until it is severe enough for symptoms to show. In the end nobody will be able to tell if someone got it specifically from living next to a golf space, from metabolic quirks, from eating 2C-D a little too often or a combination of all that.

You could only study that if many people were 2C-D users (best without any other drug consumption, so that would likely make 0 people globally) and you could find a correlation to PD. Of course such study will never exist, hence my (baseless) paranoia. It's especially shameful because I still run into stimulant relapses from time to time unfortunately, for which there may also be a link to PD (and general neuro- + cardiotoxicity) so I should just drop that and eat some 2Cs instead.
 
Psychedelics are like tools, each of them serves a different purpose in a different context.

Personally, I enjoy the phenethylamines for their warmth, mushrooms for the physical enhancement and short duration, and LSD for the sparkle and epic roller coaster of exploration within the mind.

DMT is interesting but lacks any ability to make sense of the experience.

5-meo-dipt is sexually explosive but lacks emotional warmth.

4-ACO-DMT had some unpredictable results…

I grew up on Pihkal so I have a special place in my heart for the phenethylamines.
 
2,5-dihydroxy-4-methylamphetamine

I know TMA-2 is often compared to mescaline, but to me, they couldn't have been further apart. I don't have much experience with either though. TMA-2 was also distinct from any 2C-x I tried. Very weird stuff. Should try again, but I don't like how it is uncannily close to oxidopamine if it were to be entirely demethylated to 2,4,6-trihydroxyamphetamine (unlikely but still). 2C-D I'm a bit weary of too, as it’s used in high dosages and the related putative trace DOM metabolite 2,5-dihydroxy-4-methylamphetamine was shown to be similarly neurotoxic. Not weary enough to not use it though :)
This is a loosely proposed theory. I’ve never seen direct records of this being ever found directly.
 
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