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Esoteric What Are Your Favorite Psychedelic Adjuncts?

Esperighanto

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Recently a thread on this forum had people talking about ayahuasca adjuncts, and it came up that the concept of applying adjunct drugs to psychedelic experiences is often worthwhile regardless of what the psychedelic(s) in play are. I have often administered (to myself or others):
  • Promethazine or ondansetron as antiemetics.
  • Coca tea, xanthines, amphetamines (and bupropion), racetams/noopept, and _afinils to add some energy and clarity to the experience.
  • Cannabinoids (and dagga) to synergize with the trip and round things out a little.
  • Mitragyna alkaloids and/or tianeptine, sometimes in the presence of soma to downmodulate things a little bit. Benzos work too but you often have to scale up the dose of the serotonergic to counter benzos' mild "dulling" effect on a trip.
  • Soma and/or cyclobenzaprine on their own is a beautiful mixer with psychedelics, in my opinion.
  • Intranasal oxytocin is an exceptionally brief empathogenic sparkle that I like to add in sometimes.
  • Nitrous is an exceptionally brief dissociative sheen that can be nice to add in.
  • Acorus calamus as a profoundly unique, non-specific amplifier is cool to play around with, though its carcinogenic traits make me shy away from it nowadays.
  • Kanna, cathinones like NEP, and low doses of empathogens can imbue a sort of "light" and "love" to the experience that a full dose of an empathogen sort of overlooks and steamrolls out of the way.
  • Salvia, as well as sinicuichi, can be a great way to add some spice to a trip.
  • Propranolol and clonidine are helpful for rounding out minor overstimulation, on the somatic front, at least.
I'm just generally curious, what have people here experimented with, and what did you find useful or not useful?
 
well, one that is relatively obvious would be DMT onto other tryptamines to intensify, or push further


Edit: speaking of n,n-DMT here, although others might work.
Also might work ontop of other psychedelics besides trypts like lysergamides. Not too sure about Phenethylamines though, because I think you will get a different effect there...
 
Recently a thread on this forum had people talking about ayahuasca adjuncts, and it came up that the concept of applying adjunct drugs to psychedelic experiences is often worthwhile regardless of what the psychedelic(s) in play are. I have often administered (to myself or others):
  • Promethazine or ondansetron as antiemetics.
  • Coca tea, xanthines, amphetamines (and bupropion), racetams/noopept, and _afinils to add some energy and clarity to the experience.
  • Cannabinoids (and dagga) to synergize with the trip and round things out a little.
  • Mitragyna alkaloids and/or tianeptine, sometimes in the presence of soma to downmodulate things a little bit. Benzos work too but you often have to scale up the dose of the serotonergic to counter benzos' mild "dulling" effect on a trip.
  • Soma and/or cyclobenzaprine on their own is a beautiful mixer with psychedelics, in my opinion.
  • Intranasal oxytocin is an exceptionally brief empathogenic sparkle that I like to add in sometimes.
  • Nitrous is an exceptionally brief dissociative sheen that can be nice to add in.
  • Acorus calamus as a profoundly unique, non-specific amplifier is cool to play around with, though its carcinogenic traits make me shy away from it nowadays.
  • Kanna, cathinones like NEP, and low doses of empathogens can imbue a sort of "light" and "love" to the experience that a full dose of an empathogen sort of overlooks and steamrolls out of the way.
  • Salvia, as well as sinicuichi, can be a great way to add some spice to a trip.
  • Propranolol and clonidine are helpful for rounding out minor overstimulation, on the somatic front, at least.
I'm just generally curious, what have people here experimented with, and what did you find useful or not useful?
I don’t think a drug has ever made me more sick than a time I made calamus tea, with root I got from a botanical vendor at the time. I vomited for hours, it was so miserable. The sheer smell of the drawer I kept the calamus in made me wretch for months after that.

Phenibut imo pairs well with phenethylamines, smoothing some of their stimulatory edge while adding that subtle phenibut euphoria.

Alcohol in moderation can be nice on the come up and comedown of trips.
 
I enjoy a bit of beer, or maybe some mezcal or bitters on the comedown. Ginger tea is always nice too. I find weed can be a bit too much most of the time. I haven't been too adventurous with adjuncts tbh. And although we're talking about material adjuncts here I have to say that music has always been the #1 factor for steering and flavouring a trip for me.
 
For my part, I always add cannabis in the experience. But as a daily smoker I am probably more biased with the way it affects the experience.

Besides, sometimes I like to drink one or two beers or glass of alcohol in the comedown. I found it to make it more round.

Also, but I don't consider it as an adjunct, ketamine is a special one with LSD.

And as Perpetualdawn point, the music is really the #1 factor in the experience.
 
well, one that is relatively obvious would be DMT onto other tryptamines to intensify, or push further
The first time I mixed DMT with psychs I was candyflipping, jesus that was a lot. To this day though it's a favorite triple-substance mix of mine.
I don’t think a drug has ever made me more sick than a time I made calamus tea, with root I got from a botanical vendor at the time. I vomited for hours, it was so miserable. The sheer smell of the drawer I kept the calamus in made me wretch for months after that.
Interesting, I've never fallen ill from calamus tea, though I typically just put it in gel caps when I eat it. It's one of the most unique drugs I've used, I often describe the state it induces as feeling like an alligator with my eyes just above the water, a well of potential energy waiting for the trigger to convert the potential into kinetic energy.
Phenibut imo pairs well with phenethylamines, smoothing some of their stimulatory edge while adding that subtle phenibut euphoria.
Gabapentinoids are fantastic mixers, have you ever experimented with them intranasally? I've found gabapentin, floribut (warning, likely very toxic) and mirogabalin to all function significantly better when intranasally administered.
And although we're talking about material adjuncts here I have to say that music has always been the #1 factor for steering and flavouring a trip for me.
I believe it was Sasha Shulgin who said "music is the key", in reference to exactly this point. I wonder to what degree the production of music (or playlists) will be a relevant skill for psychedelic guides in the future.
Also, but I don't consider it as an adjunct, ketamine is a special one with LSD.
Dissos and psychedelics really do mesh together well, 3-MeO-PCP with 2C-B (and especially MDA), or 3-HO-PCP with allylescaline and/or LSD are some of my personal favorites. CanKet (2F-O-PCE aka 2-FXE) alongside 25C-NBOMe and LSD was also a fascinating experience. Just LSD with ketamine was the foundation of three of the most intense and mystical trips of my life, every week for three weeks administering about 1.5-2.5mg (not mcg) of LSD alongside maybe 600 or so milligrams of ketamine got me there, alone in a dark house late at night.
 
Dissos and psychedelics really do mesh together well, 3-MeO-PCP with 2C-B (and especially MDA), or 3-HO-PCP with allylescaline and/or LSD are some of my personal favorites. CanKet (2F-O-PCE aka 2-FXE) alongside 25C-NBOMe and LSD was also a fascinating experience. Just LSD with ketamine was the foundation of three of the most intense and mystical trips of my life, every week for three weeks administering about 1.5-2.5mg (not mcg) of LSD alongside maybe 600 or so milligrams of ketamine got me there, alone in a dark house late at night.
Yeah, I totally share your point of view. As I do not try as much dissos/psychs, I stuck with ket/LSD but clearly it's my favorite one.

At the peak it sends you in another dimension, a few lines during the comedown or at the end of the peak is also clearly a good one too! With a little bit of cannabis of course to round up the experience and here we go!

In the future I clearly will try a few more dissos/psychs, specially the PCE analogs are on my list as they seems more psychedelic!
 
Gabapentinoids are fantastic mixers, have you ever experimented with them intranasally? I've found gabapentin, floribut (warning, likely very toxic) and mirogabalin to all function significantly better when intranasally administered.
I’ve never tried any gabapentinoid intranasally. I don’t like putting things up my nose unless I really have to. Do they boof well?
 
I’ve never tried any gabapentinoid intranasally. I don’t like putting things up my nose unless I really have to. Do they boof well?
I had a complete proctectomy or else I'd have already tried.
In the future I clearly will try a few more dissos/psychs, specially the PCE analogs are on my list as they seems more psychedelic!
3-HO-PCE was one of the most emotionally cathartic drugs I've touched so far.
 
3-HO-PCE was one of the most emotionally cathartic drugs I've touched so far.
🤔sounds interesting!
Unfortunately this one isn't available for me, I may have the meo/me one or some 3-ho-PCP. I will see when it's the time for me to order some new stuff!
 
MXE paired well with everything. I don't like cannabis that much around the peak effects because it provokes extreme anxiety for me these days. MDA and MDMA of course pair well with most everything and round out the sharp edges if you're in a group setting. But they can overpower the trip so I don't like stacking peaks. I typically consume MDA when the initial peak feels like it's tapering off. I've done it the other way around and that's fine to. But I don't like coming down off of it in the middle of another strong experience.

Phenibut, gabapentin and lyrica can pair well but I'm weary of them with other substances besides weed and opioids because I've gotten into seizure territory with them more than once. It's easy to over do it. I've snorted lyrica before and it works okay but not as good as taking it orally. It just ends up clogging up the nose and I think most of the effects are caused by the drip. Just oral dosing with extra steps.

Opioids are always great to deal with the body effects of things like LSD. Since it's pretty rough on anyone that has chronic pain. Shrooms do not have that problem they work as a good pain killer on their own. MDA/MDMA also seems to be very effective at killing pain on its own. I prefer sedating opioids in combination. Gold standard is morphine closely followed by real heroin. Stuff like oxycodone and hydrocodone I save for the come down. Since they have a bit of a speedy edge to them and I already have enough of that going on.

Kratom can be okay but it's usually projectile vomiting time for me if I take it too close to dosing something like MDMA or LSD. It's really really rough on the stomach in combination with those for some reason. Puking up a bunch of black/brown crap while rocketing up on MDMA isn't the greatest time. I'm not sure if this is due to getting older and my body having a harder time with MDMA come-ups or it's caused by the kratom itself. It happens every time now even when I've been taking kratom daily for years. I figured out it's best to try and hold down the MDMA for about an hour. After an hour I'm better off going to the bathroom and puking otherwise I'm going to have a bad night.

If I'm going to take benzos I prefer long acting ones. Valium being my favorite. Xanax is a bit of a waste ime. Save those for the come down. I feel the same way about K. I don't really like any of the other dissos I've tried but I haven't taken many since MXE vanished.

MXE will always be the best. Stuff was perfect with everything (and by itself). You could take small bumps casually and feel perfect no matter what else was in your system. Or you could go into the hole and flavor it with LSD or whatever else you were taking. I never combined it with MDA but I'm sure it would have been great with that too.

Other than that: Lots of tobacco. Menthol cigarettes are an absolute must.
 
I don’t think a drug has ever made me more sick than a time I made calamus tea, with root I got from a botanical vendor at the time. I vomited for hours, it was so miserable. The sheer smell of the drawer I kept the calamus in made me wretch for months after that.

Phenibut imo pairs well with phenethylamines, smoothing some of their stimulatory edge while adding that subtle phenibut euphoria.

Alcohol in moderation can be nice on the come up and comedown of trips.
I had the same experience with acorus calamus, I used an ethanol extraction and concentrated the tincture (so it wasn't the alcohol that was the problem). I vomited repeatedly for hours.

My excuse was that I was young and stupid at the time.

Now I'm just old and stupid.
 
Im interested to try adding lions mane and ginkgo bilboa to a trip. My short term memory problems make most psychedelics impossible to integrate the experience so I mostly get nothing from them. Except mescaline which doesn’t seem to have negative effects on memory. Lysergsmides tho. Well bury me because my short term memory is dead on those. Mushrooms are middle of the road but the higher the dose the worse of a time I have.
 
Im interested to try adding lions mane and ginkgo bilboa to a trip. My short term memory problems make most psychedelics impossible to integrate the experience so I mostly get nothing from them. Except mescaline which doesn’t seem to have negative effects on memory. Lysergsmides tho. Well bury me because my short term memory is dead on those. Mushrooms are middle of the road but the higher the dose the worse of a time I have.
I found tetrahydroharmine, noopept (and other racetams), and galantamine to all help my memory when on psychedelics, I wonder if any of those would help you. The last two were the most effective for me, tetrahydroharmine could be pushed too far and just feel like super sharp, clearheaded harmaline if I took too much.
 
I was thinking about past experiences with psychedelic and something goes through my mind.

I remember on a low dose (50mcg) eating chocolate with a high amount of cocoa and it clearly was an experience in itself and create a feeling never experienced before.
I don't really know how to describe it precisely, but it was different from the taste enhancing one can encounter on psychedelics.

Sorry of it's out of topic but it seems an interesting topic to point and maybe some of you have experienced something like this before!
 
Sorry of it's out of topic but it seems an interesting topic to point and maybe some of you have experienced something like this before!
Acid induces what I often refer to as "psychedelic munchies" for me, I noticed it the first time when I was off roughly a tenstrip with the gang, and like I did every day, smoked 2-3.5 grams of dabs out of a lossless enail. Usually I wasn't eating much in the first place, as the overuse of cannabis and constant usage of serotonergics (plus ephedrine) had fried the fuck out of my natural sense of appetite. I almost involuntarily found myself looking in the fridge, and I spotted an M&M brownie that my fiance had made and overcooked slightly. He's a real perfectionist in the kitchen and didn't end up eating any of it, and it was one of those 8 or 9 inch square pyrex dishes. I took it out, tapped it upside down so the whole thing fell out, and I just ate the entire thing like it was some sort of oversized brownie cookie full of M&Ms. The manner in which I ate that thing was fucking reprehensible, I can't lie dude. Primal hunger overcame me and the entire thing was housed, standing right there over the kitchen counter like some sort of starving gremlin who finally got his grubby little acid hands on some chow. Since then, I've noticed it occurring with a ton of things, allylescaline, 2C-B, DOM, LSD, etc. all exhibit it but they all do to different extents, and some things are more oriented towards either sweet, savory, or bland foods for some reason.

I've also played with cacao ceremonies, yerba mate, guarana, coffee, and pure caffeine (and other pure xanthines) in combination with various psychedelics to see how they affect things. Eating a large amount of straight cacao leads me to a similar state as when I coadminister a sizeable dose if theobromine, a smooth and euphoric stimulation that somehow seems to enhance the visual and tactile effects of psychedelics (though especially indolic ones like LSD and psilocybin), but the cognitive side of things is rather unaffected other than a slight increase to cognitive clarity, like I'd normally get from caffeine/methylliberine.
 
Acid induces what I often refer to as "psychedelic munchies" for me, I noticed it the first time when I was off roughly a tenstrip with the gang, and like I did every day, smoked 2-3.5 grams of dabs out of a lossless enail.

Usually I wasn't eating much in the first place, as the overuse of cannabis and constant usage of serotonergics (plus ephedrine) had fried the fuck out of my natural sense of appetite. I almost involuntarily found myself looking in the fridge, and I spotted an M&M brownie that my fiance had made and overcooked slightly. He's a real perfectionist in the kitchen and didn't end up eating any of it, and it was one of those 8 or 9 inch square pyrex dishes. I took it out, tapped it upside down so the whole thing fell out, and I just ate the entire thing like it was some sort of oversized brownie cookie full of M&Ms. The manner in which I ate that thing was fucking reprehensible, I can't lie dude. Primal hunger overcame me and the entire thing was housed, standing right there over the kitchen counter like some sort of starving gremlin who finally got his grubby little acid hands on some chow. Since then, I've noticed it occurring with a ton of things, allylescaline, 2C-B, DOM, LSD, etc. all exhibit it but they all do to different extents, and some things are more oriented towards either sweet, savory, or bland foods for some reason.

Oh I love eating on psychedelics once I'm past the peak. I do find LSD a bit on the anorexic side as far as psychs go, but it's not as bad as mescaline which is the most anorexic psychedelic I've had. The 2C-X drugs though? They are fabulous for eating once past the peak. I've remarked before I'd love to take a museum dose of 2C-B before going to a fancy dinner. There was a time I was taking mushrooms frequently, almost always at night, and I loved eating diner food during the come-down.

A funny story I have is when a friend and I took 20 mg of 2C-I together. The visuals were so intense as is usual with this dose, but then my friend sheepishly asked if I was hungry and if that was even "possible" while tripping hard. I assured him that 2C-I often gives me an enormous appetite, and it was ok if he wanted to eat. So we ordered pizza. When it arrived, we were still tripping. We opened the boxes, and the pizzas toppings were swirling around like crazy. Shit was morphing too. It looked like we were about to eat something completely alien, something that wasn't completely dead yet. We looked at each other and laughed out-loud at the absurdity of it, but eat we did. And in fact, IIRC he polished off his entire pizza in less than an hour.

Having read your post, I hope you get to try 2C-I some day and get to enjoy its wonderful appetite stimulating effects.

As for me and my adjuncts? For me it's probably just cannabis---and typically lots of it in the later stages of the trip.

Edit: I've been meaning to try tetrahydroharmine with trips but haven't gotten around to it yet.
 
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