I've done it before so I know I'm not enzyme deficient. I'm not mixing it with anything and not on any medications that would interfere with it. I'm taking 708 mg from 2 bottles of 4oz Tussin cough syrup which would be 8.8mg/kg for me. I havent take it in months but I do remember it has a bodyload so realistically what do you think the odds are of dying from something like cardiac arrest, a stroke, kidney/liver/pancreas failure or something like that during it?