Stimulants Wellbutrin For Depression

[Jabberwocky]

Unfortunately, in the last 4 weeks I've averaged 4 hours sleep....
Per week.
Not sure how much longer I can take this.

The temptation is to immediately taper and save the rest for party nights.

How much do you take daily?

 

[Dextro .45]

I had to look up what methylphenidate is, looks like its a controlled med and I wouldnt want to take it. I basically just felt I needed something to keep myself from ...... I think the Wellbutrin is working good enough.

Bupropion has negligible effects on Dopamine and is more of a Norepinephrine action along with others

Methylphenidate (Ritalin) was marketed as an antidepressant in the 1950’s , 3-4X Dopamine release over Norepinephrine.


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[Mycophile]

Im thinking the Wellbutrin must be working. Last week i was SAD, constantly dwelling on something that happened 20yrs ago, regretting what I did, wishing to go back in time. It was killing me. So much so that I had to make a Drs appt and ask for the Wellbutrin.

The sadness is much better since starting. The thing from 20yrs ago still pops up in my head but i dont find myself dwelling on it as much, its like my mind quickly switches to what im doing at the moment.

Hey. I just started 150XL Wellbutrin and so far it's just making me jittery and like I cant figure out how much caffeine to drink on it. I always drink too much coffee and tea and now I guess I need to cut back but I don't know how much is ok.

Did you ever have that feeling and if so, did it go away?

But most of all I'm wondering if Kratom still works well for you on your Wellbutrin? Cause I haven't used Kratom since I've started Buproprion but I love Kratom and I've heard some reports of Wellbutrin fucking with its ability to work. So since you are talking about combining the same three things I am (Kratom, Wellbutrin and Caffeine, though I'm also on prozac and Klonopin) I'm interested in knowing.

And when you first started Wellbutrin how long did it take for it to start having its desired effect? I know this is an old thread, so is it still helping you?

 

[4DQSAR]

We are all different.

I've known people who said bupropion (Wellbutin) worked amazingly well and I've known people for whom it offered no relief from depression whatsoever.

I think it worth pointing out that the MOST effective antidepressant (amitriptyline) AKA 'the gold standard' is efficacious in less than half the patients prescribed it. As far as I know even now new antidepressants are measured against amitriptyline... but often in a misleading way i.e. the highest prescribable dose of the newer antidepressants are compared to the lowest dose of amitriptyline generally recognized to be active as an antidepressant.

If people wonder why amitriptyline is now often religated to second-line treatment, the reason is simple toxicity. If someone takes their entire supply of most modern antidepressants, they may become ill and may end up in hospital. But if someone consumes their entire supply of amitriptyline, the outcome is often a fatality.

So while it's fine to comment that a given medication did or didn't work for you, unless you can provide supporting data, don't assert a given antidepressant is or isn't effective in all cases. A cohort of one is of no statistical value.