Stimulants + THC is known for causing tachycardia which leads to panic attacks. When I first tried Vyvanse it was 40mg and I took 3 tokes from a smoke and had to think myself out of 3 panic attacks
Weed is fine with any drug in my experience... its good to keep a fast acting benzo on hand if ur blazing with a stimulant "for any panic attacks if ur prone to them"
Ive had anxiety issues all my life but I love that combo, it actually seems to curb weed anxiety and takes away the lethargic couch lock feeling while still keeping the pros.