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  • BDD Moderators: Keif’ Richards

Vyvanse kick in time when speed balling

xbloodwhipx

xbloodwhipx

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Jun 22, 2011
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So i need to know about dosing times when speedballing with vyvanse, tommorow morning i plan to take 150mg of nucynta and 150mg of vyvanse, how long after taking the vyvanse can i take the nucynta so they will peak at about the same time?
 
I am not sure I would mix an amphetamine with Nucynta due to Nucynta's re-uptake inhibition of norepinephrine. It could cause your seizure threshold to lower to some extent I would guess. I am not too versed in how Nucynta works, but I do know it works on norepinephrine as well as on the opioid receptors, and with the NRI action of Nucynta I am guessing lowers the seizure threshold like most NRI's do. Just a warning. I have heard very mixed things about Nucynta, in general, and it seems like a dirty drug.
 
Take nucynta about 1 1/2 hours after taking the vyvanse. Usually vyvanse peaks around 3 hours and holds steady for awhile. Nucynta peaks before 2 hours in.
 
Hard to say exactly. without previous history of seizures i certainly wouldnt worry too much about it. Its effects outside of being an agonist of μ-opioid receptor are not well known or documented. The effects on nor-epinephrine are small at most. The mechanism of action is not fully known. There are more reports of seizures coming from this painkiller than others... but others are not by any mean notorious for causing seizures.
 
Well anyway i took it, i took the vyvanse at 7:30 am and the nucynta at 10 pm,
Could I redose now, its 7:00 pm
 
Yea but it took the vyvanse at 7:30 in the morning, and im starting to comedown, do you guys think its been long enough to take 150mg more nucynta (i took 150mg at 10 in the morning.
Its 9 pm now
 
Sure, it's "safe," but it's a waste of drugs, imo. The Vyvanse and am dose of Nucynta have depleted your presynaptic DA and NE stores, you need a good meal, water, and a nice sleep to replenish it.
 
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I dont think i will be sleeping anytime soon... i layed in bed for 2 hours, im not even tired :(
Anyway i didnt take the rest of the nucynta because i got paranoid about serotonin syndrome.
 
Nucynta doesn't really release that much serotonin. Tapentadol and O-Des have half the 5-HT releasing abilities of Tramadol, but the same NE reuptake abilities.

It's still good to play it safe, as Nucynta definitely releases 5-HT, and you're taking a lot of it. 150mg is basically equivalent to 45-50mg hydrocodone, and you're thinking about taking it twice today, watch your ass, OP. Nucynta can cause some nasty dependence, worse than hydro...
 
I can see how bad the dependence could get, the next day (today :P) im on 150mg again....
I dont plan on making this a habit but we never really do "plan" on addiction happening.
With that being said im going to stay away from hydro and nucynta for awhile
 
Good idea to stay away from it. I remember the other week, you assured Token and I that you've used Nucynta only once a week for a long time after we warned you of its addictiveness. Looks like it's quickly creeping up on you; recreational opiate use can be insidiously addictive like that, stay far away from using opiates for fun, imo.
 
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