Veterinary vs. Human grade Ketamine? (for depression)

[Rosarywater]

I'm interested in ketamine for relieving severe depression and am wondering if there is any significant difference between the veterinary and medical grades. Dr. Fruitman, a NYC doctor who is doing this therapy, says on his website that the negative effects of K are because a) recreational users take very high doses and b) they use veterinary grade.

If one dosed it right, would it still be dangerous to use vet grade K for depression?

***btw I am asking here because I'd rather not pay several hundred dollars to hear it from the doctor.

 

[Seyer]

Veterinarians use medical grade Ketamine. Not sure what you even mean by "human grade" K. If its in a pharmaceutical vial, then Ketamine is Ketamine.

 

[Rosarywater]

https://trifectahealthnyc.com/our-services/ketamine-treatment-for-depression/

There are some vials like the ones pictured here that specify they are only to be used in cats or subhuman primates. I'm all for there being no difference, just wanna be sure!

 

[ungelesene_bettlek]

in veterinary medicine, usually racemic ketamine is used, in human medicine, nowadays mostly s-ketamine.

 

[Seyer]

https://trifectahealthnyc.com/our-services/ketamine-treatment-for-depression/

There are some vials like the ones pictured here that specify they are only to be used in cats or subhuman primates. I'm all for there being no difference, just wanna be sure!

Id honestly be surprised to see a label that doesnt say that.

 

[sekio]

There's no difference between ketamine for human use and ketamine for veterinary use. Same formulation.

Some doctors use S-ketamine for humans primarily because they think it reduces the indidence of side effects. But they use racemic K sometimes too.

 

[any major dude]

Interesting. In most respects S+ ket is noticeably more potent, but to my knowledge, no study has looked at the different effects of either isomer vs the racemate. Would love to study this myself, as I have a suspicion the R isomer may be equipotent for antidepressant purposes.

 

[.:Holy::Toast:.]

There's this thread from awhile back

http://www.bluelight.ru/vb/threads/447697-Ketamine-Subthread-Isomers-R-and-S-Ketamine

There it says S+ isomer k has more neuroprotective properties, and has a greater binding affinity for certain NMDA receptors.
There's no comparison of R- ketamine versus the racemate however

 

[tomatalli]

You can get ketamine prescribed for depression?

 

[Folley]

Ketamine is Ketamine.

I don't actually think that's true the way it is with something like MDMA... with the different isomers there can be quite a bit of variance, and I know that different manufacturers use different preservatives so that may play some part.


but yeah, racemic ketamine HCl and benzethonium chloride is racemic ketamine HCl and benzethonium chloride...... lol

 

[sekio]

The amount of benzethonium chloride (maybe 0.5%... more like 500 ppm) in a typical dose of K is non active in humans. That, and as a charged quat ammonium compound it's going to have a hard time making it through the BBB.