An excellent set of questions! I'll try my best to share my experiences.
I have had a number of breakthrough-type experiences, albeit not on shrooms or n,n DMT, but on similar psychedelic tryptamines at high doses, (ex. 4-HO-Mipt 60mg oral + 25mg smoked at the peak). The general theme of these experiences is one of connectedness to the greater human machine, of seeing oneself within one's greater context, as a human being among billions of other human beings, as a speck on a planet, of the planet as a speck in the galaxy, etc. Thoughts generally become eternal, cosmic, and astonishing. This, combined with the sheer intensity of the visuals, which can completely defy one's regular perceptions, really does push the boundaries of one's psyche. I've felt at times worried that I may never come down, that my experiences will be forever and traumatically burned into my mind, that the assault of visuals will never subside, but these fears, to my knowledge, are unfounded. I have never had an experience linger with me for longer than a day, at least with a tryptamine, though the realizations and insights do come with into the sober world, and can really give you something to chew on.
This is why set and setting are so important. A big dose is challenging, and you'll want to be around good friends in a calm, safe environment. And I would say for certain, don't go it alone, if you come across a challenging set of ideas, it's essential that you're able to talk about them with someone you trust. I don't exactly know if it's possible to develop a psychosis with the substances you've described, but I would suggest that you make sure you've got your ducks in a row before you leave. Make sure you've built up to it, or it'll take you by surprise, big time. But, it sounds like you probably have.
As for permanent effects, not sure if this is positive or negative, but I think I am seeing differently on the back of 6 months worth of experiences. Physically seeing differently. My eyes are drawn to perfect geometric patterns, and my brain seems to want to generate geometric visuals when given a place to do it, like, say, the empty space on this page. I notice the "rainbow static" on nearly everything as well, the world seems altogether more vibrant and colorful. It's at a low level most of the time, and is never disruptive or unpleasant. I would attribute this to the possibility that the strong psychedelic visuals on these breakthrough trips have taught me "the art of seeing", so to speak.
The content of my thoughts has also shifted, well, upwards, so to speak. I now make connections to the greater cosmic context than I would have before. I see psychedelic influences everywhere, I find myself more interested in math and science, in psychology and the mind. I feel less able to tolerate stupidity, I am disgusted by television advertisements, I am more able to see when I am being manipulated. I crave the real, the true and the beautiful, and I avoid the fake and the corrupt. All of these qualities of my thinking have been accentuated by my use of psychedelics, and never more so than on the back of my breakthrough experiences.
As for limitations of the ego, yes, I would say that they have decreased. I feel now that my ego is more resilient and elastic, that I am better able to handle massive shifts of consciousness than before my breakthrough experiences. I also feel that my ego has shrunken significantly, that I'm beginning to become a more selfless, more open person, with less anxiety and paranoia.
I also used psychedelics to get off anti-depressants, and I feel much better now. My thinking is that my experiences have made me psychologically stronger, so that I no longer need the medication to get through the day.
Overall, I can't think of any major warnings to give you, or any reason why you shouldn't partake. Just make sure you're ready, and it should be a good experience. I would highly recommend the 5 dried grams over the dmt as a first breakthough experience, just because I think you would get more out of it. To my understanding, shrooms are more of a teacher, dmt is more of a mile-a-minute thrill ride. Thanks for posting, this has given me a good opportunity to reflect upon my own experiences.