Valium 150mg & Codeine 600mg (I know it's boring drug combo)

[Anon54]

1:30 drank 150mL of white GFJ maybe. I probably didnt need that much cuz wikipedia says 250mL is sufficient but im not sure if it was 100% pure white GFJ. I did this to increase the effect 1.5x & increase the duration. had to take a piss a few times after drinking that much GFJ. It wasnt very easy to drink but im starting to get used to the taste. maybe i went a bit overboard with how much i drank but I want it to work
Quoted from www.erowid.org

One psychoactive drug that grapefruit juice is known to affect is valium (diazepam). In a paper by Ozdemir in the European Journal of Drug Metabolism and Pharmacokinetics in 1998, they found that 250ml of grapefruit increased the peak concentration by 50% & increased the time to peak from 1.5 hours to 2 hours.

I've also had some milk thistle which Ive read can potentiate benzos.http://www.pointofreturn.com/drug_interactions.html

Milk Thistle
Milk thistle may interfere with many medications and increase them to dangerous levels because the same liver enzymes break down the herb. Milk thistle should not be combined with allergy medications, drugs for high cholesterol, anti-anxiety agents (alprazolam, diazepam, lorazepam, clonazepam, Temazepam), antiplatelet and anticoagulant drugs (blood thinners), anti-seizure medications, anti-psychotics, antidepressants, hormones and others.

2:30 Took 150mg of Valium, it's suppose to peak 1.5 hrs after taking GFJ instead of an hr. This is a very high dose for my. usually I take 75mg

3:00 Had a strong cup of tea & a smoke while waiting for the codeine in the freezer. I only feel slightly calmer at this point. I do the CWE close to perfect. I squeeze it though a wet hanky over a bowl as a first filter stirring thoroughly before hand & squeeze every last drop out before putting it through a wet filter so it doesnt jam the filter up. I get the same amount of water out as I started with so im assuming im getting close to all of it. I never usually use more than 80mL-100mL of water but i had to use about 140mL because I had 60 tablets. so that would equal to a little under 2g apap at room temp. but im cooling it down to the point where it's almost feezeing so it might be like taking 1g of apap.
nothing to worry about after all on the otc tablets u get here it says to take 1 or 2 tablets. 2 being 1g.

3:30 drank the 600mg codeine. I dont mind the taste of it these days but it was a bit stronger cuz i only usually do 400mg & its a dispute about the ceiling effect. Theres a dispute about the ceiling dose nobody knows if it's correct.
from www.wikipedia.org

Codeine is metabolized to C6G by uridine diphosphate glucuronosyl transferase UGT2B7, and, since only about 5% of codeine is metabolized by cytochrome P450 CYP2D6, the current evidence is that codeine-6-glucuronide (C6G) is the primary active compound.[20] Claims about the supposed "ceiling effect" of codeine doses seemed to rest on the assumption that high doses of codeine saturated CYP2D6, which prevented further conversion of codeine to morphine, which is simply incorrect since we now know that codeine-6-glucuronide (C6G) is the main metabolite responsible for codeine's analgesia.

codeine peaks at 1 hr so should get the valium & codeine peak at almost the same time.
Ive got 600mg of codeine for tommorow morning. I wont have the GFJ because it's uncertain whether codeine is potentiated by GFJ.
In this list of GFJ drug interactions it says that it potentiates codeine. we'll wait & see
http://en.wikipedia.org/wiki/List_of_drugs_affected_by_grapefruit

Codeine and Tramadol.[10] It reduces the amount of codeine converted by CYP3A4 into norcodeine thus increasing the amount metabolized into morphine.[citation needed] Morphine itself, however, is not affected by grapefruit juice, as it is not metabolized by the cytochrome P450 system

This should peak at 4:00 because i added the GFJ instead at 3:30 & the codeine should peak at 4:30 but generally it only taking 30 mins for it to peak with me. Sometimes I feel it within within 5-10 mins. Maybe placebo
I find codeine to be weaker than oxy but it has a better feel. 400mg is suppose to equal 40mg of oxy. I get in a good place with 120mg of oxy but Ive had up to 160mg. I must like morphine better. Ive had a little but of h before but it must have been poor quality or it wasnt enough cuz i only had 0.1g each time. (I think regular codeine use does give ya a tolerance to h)
anyways im going to have another cup of tea & a smoke I'll some more to this when the codeine & valium start to peak. Its the highest dose of codeine ive ever had is 600mg & the highest dose of valium ive had is 150mg so it should be interesting to mix em together & see how it goes especially with the GFJ which i dont usually take.

4:00 Having another cup of tea & a smoke. I'll come back soon to let u know how it goes.
4
4:45 Well Im feeling relaxed but nothing special. to much tolerance to benzos even though i rarely do them. I though i would get an awesome high with such i high dose. I had a friend that had to go to sleep after only taking 2mg of xanax but it was his first time. I shouldnt have recommended so much. Might have to get on the harder stuff to catch a good time like oxys cuz they dont have a ceiling effect. I dont seem to have a stronger effect from the codeine from 40mg-600mg but I had codeine yesterday too. I wonder how long it takes for the tolerance to go away cuz i was nodding off a cwe on a prescription 20 pack of panadeine (30mg codeine/500mg apap) after a yeah off opiates.
This is my first trip report. next time i'll do something better like when im on acid or something. Had some pretty interesting experiences when i was younger occasionally taking dxm too but i dont really do psychedelics these days.
I suffer from GAD & i take an antipsychotic every night. It seems like ever since i started them benzos dont work as well because im used to the stronger sedation.
Well i feel well, carefree & might just watch tv.
thanks for reading but it's not really a very interesting trip report ah. I was hoping for something a little better. I mean 30 valiums, i only occasionally take them. like 3 times a month. i cant understand why i cant get back to when 15 done the job. It must takes months for the tolerance to go away. I always had a natural tolerance to valium. I started at 7 & it barely did anything & i actually get less wasted when i drink after taking valium because i drink slower but of course i wouldnt recommend that unless u have a tolerance & u take the pills before u drink & not after.
anyways im gunna chill & watch some tv.
sorry if ive wasted your time with a a pretty unexciting trip report.

5:00 Feeling a little sleepy now. might lay sometimes opiates & benzos work better if ya lying down.

 

[Mercc96]

Must admit one of the best opiate highs I've ever had was a simple etizolam, various antihistamines, pregs and dosing about 400mg of codeine every couple hours for about a day. Felt high for ages.