Grand Touring
Bluelighter
- Joined
- Apr 5, 2011
- Messages
- 80
Two problems I encounter with attempting to increase peak blood/plasma concentrations of dexro:
1. Taken p.o. with an alkalizing agent slows absorption and increases Tmax.
2. Taken p.o. with an empty/acidic ionizes the salts making the stereo/isomers less lipophilic.
I've found that allowing the salts dissolve in the slightly acidic environment of my saliva first, allows for "ion trapping", turning it into a solution, and making it more potent without giving up longer absorption rates when ingested.
Any ideas?
1. Taken p.o. with an alkalizing agent slows absorption and increases Tmax.
2. Taken p.o. with an empty/acidic ionizes the salts making the stereo/isomers less lipophilic.
I've found that allowing the salts dissolve in the slightly acidic environment of my saliva first, allows for "ion trapping", turning it into a solution, and making it more potent without giving up longer absorption rates when ingested.
Any ideas?