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Opioids underwhelming experience with oxy - advice?

PL622

Greenlighter
Joined
Jan 7, 2026
Messages
2
I'm opiate naive and seem to get very weak effect from opioids/opioid like drugs, though i respond normally to other drugs like shrooms/MDMA/benzos/stims/alcohol like ritalin - though I am a very occasional use of each (like twice/three times a year MDMA, once a month benzo and alcohol, perhaps once a month or a bit more psychs, stims almost never - maybe once a year).

have a strip of 10mg UK Napp oxycodone ER, 1 80mg oxypro, and some DHC as well as kratom powder.

I checked the forums and starting dose advice so started slow by crushing the 10mg pill and swallowing (supposedly the UK napp oxycodone ER mechanism is desroyed by crushing). Had no subjective effect at all.

A couple of weeks later I tried again so crushed a 10mg pill very fine crushed and snorted it (I wondered if my GLP-1 injection would have interfered before). I did feel some effect from this, but very mild so i ended up snorting another 10mg but this didn't seem to add much to the experience other than giving me a good sleep that night. I was sort of bordering on feeling comfortable with relaxed muscles, but it wasn't mindblowing or euphoric in any sense.

A month or two later, and in the meantime stopping GLP-1 injecctions, I tried again with 20mg crushed after a light meal. This time I got a similar feeling to the snorting, but again it was pretty underwhelming - enjoyable, but nothing to write home about. I added around 5 - 8mg from the oxypro this time - peeled off the coating and crushed just under 1/8 of the pill and snorted it. It didn't seem to add much or anything to the experience. I definitely felt relaxed, and a bit wobbly and sedated, and it was a pleasant feeling - but this time sleep didn't seem to be so easy and again it was underwhelming compared with the euphoria people report. I am sure that these are legit UK pharma btw.

Separately (weeks in between), I took around 90mg - 120mg dihydrocodeine (can't remember exactly) and have also increasingly tried larger amounts of kratom up to 8g, toss and wash. Both of these produced very mild effects - definitely some effect, but pretty weak in all (DHC was almost nothing).

I wondered if it is related to the GLP-1s as I've noticed delayed onset and a higher threshold with edibles- but the other occssion i had stopped the GLP1s and snorting also produced smaller effects. As an aside, I don't edibles any more as weed/THC just makes me paranoid and I just don't enjoy it unfortunately. Wish I did or could find the right strain but everything is just so strong and feels super aggressive these days. I abused cannabis in my teens/20s but stopped as it started getting me really paranoid when i was smoking. Any advice here? :)

My question is - does it sound like I'm just someone who doesn't get much from these class of drugs? My experience seems much weaker with what people commonly report. It would not particularly bother me as I won't be making a regular habit of this as I am acutely aware of the dangers (hence why i made sure i wated a long time in between each). But equally, I was thinking of increasing the dose to see if i could get stronger effects, but frequently read that 30 to 40mg oxy is a big amount for someone opiate naive and so don't want to risk it if that's dangerous.
 
You may just be insensitive. The first time I did oxycodone I didn't have any tolerance, and I took 40mg. This is absolutely not recommended, but I knew from prior experience to other opioids that I was naturally somewhat tolerant and needed bigger doses than most.

It could be that these drugs just don't do it for you. It could be dose-related. We can't possibly know.
 
Thanks for the reply. I wonder if I'm similar to you - thing is I don't want to up the dose, expecting a better high, and get into dangerous territory. Perhaps I'm just expecting too much from the experience.
 
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