• Select Your Topic Then Scroll Down
    Alcohol Bupe Benzos
    Cocaine Heroin Opioids
    RCs Stimulants Misc
    Harm Reduction All Topics Gabapentinoids
    Tired of your habit? Struggling to cope?
    Want to regain control or get sober?
    Visit our Recovery Support Forums

Opioids Ultimate OTC Potentiation Recipe for Oxycodone!?

(I cleared my inbox. And I don't know what AFAIK means.) I haven't used Aleve the last several times, especially with the Hydro. I really just drink tons of WGJ, take a gram of Cimetidine with tums, and add a first gen anti-histamine like 37.5mg Diphenhydramine.

I do take the 60mg DMX/day to see if it lowers my tolerance. And I also take the Claritin (Loratadine) and Allegra (Fexofenadine) several hours prior because the itch is usually pretty bad for me. Do you think these 2nd and 3rd gen anti-histmamines are affecting the high? I just figure why not take them to help with the itch if they aren't affecting the opiates. (And then, of course, I take my Diazepam and Triazolam for sleep at night and my SNRIs in the morning. But I didn't think any of these drugs would interfere.)

***I don't take my regular Neurontin (gabapentin) starting two days before because studies say it decreases the BA of Oxy.***

Anyone know if the same applies to pregabalin?
 
DXM about 30 minutes prior has always worked wonders for me. And also diphenhydramine, but thats really only if I want some great sleep along with my nod. I always wake up feeling refreshed and happy.
 
^ DXM is not really a potent potentiator. It is more for preventing tolerance buildup via NMDA antagonism.

Then it's a great synergizer because even at the recommended dose I noticed a noticeable difference in the high.
 
After a WEEK of reading up on this topic (including the entirety of the Mega Opioid Potentiation Threads), talking to as many people on here and elsewhere as I can, this is what I've come up with. I'm about to try it later today (I started days ago...). Before I take my dose, I'd like to hear your thoughts. I can share some in-depth explanation if any of you have questions from my research.

Step 1) Preferably consume as much WHITE Grapefruit Juice as possible starting even 5 days before taking Oxy.
Step 2) In the 24 hours preceding Oxy dose, drink a whole gallon of white grapefruit juice (And a liter or two of tonic water if it works for you...). Most likely drinking a half gallon of WGJ juice the night before with 500mg Cimetidine followed by 2 Tums. Then the day of dose, drink the other half gallon of WGJ juice with another 500mg of Cimetidine followed by 2 more Tums.
Step 3) 2 - 4 hours prior to dose, take 30mg Dextromethorphan HBr and 4mg Chlorpheniramine Maleate.
Step 4) 1 - 2 hours prior to dose, again take 30mg Dextromethorphan HBr and 4mg Chlorpheniramine Maleate. (Be careful if pills contain acetaminophen!)
Step 5) 30 minutes before take 25mg Diphenhydramine HCL (or 12.5mg Doxylamine Succinate) and 330mg Naproxen
Step 6) Take Oxycodone dosage according to personal tolerance and desired high. (Be sure to have eaten 3 hours prior.)
Step 7) Load again on Cimetidine (400mg) and Tums every hour. (And possibly take one more 25mg Diphenhydramine? More WGJ?)

If you're curious, check out my two threads on this topic with deeper discussion and explanation here: http://www.bluelight.org/vb/threads/725827-Oxycodone-Potentiation-Recipe-Questions-(e-g-Is-it-safe-)

And here: http://www.bluelight.org/vb/threads...lp-(Opioid-Questions)?p=12411300#post12411300

I'd also add a table spoon of baking soda mixed in juice or water right after dosing to increase the BA. It could be tough to swallow so I notice it is far more tolerable when mixed in with carbonated mineral water like Perrier or San Pellegrino.
 
Top