I'm a big guy, I weight around 230 pounds. I also take 75mg of Effexor XR in the morning for anxiety. My friend is giving me a blotter of 25i-NBOMe that is 1000 ug. My question is should I wait until tomorrow and skip my Effexor to take it or can I take it tonight cause I heard Effexor can take away from a trip? Also I'm wondering if Ill even feel 1000 ug if I'm 230 pounds.
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Trying 25i-NBOMe, but I got some questions
- Thread starter Naytahn
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GreenMachine
Bluelighter
i dont have any experience with combining effexor and psychedelics but i would be careful because little to NOTHING is known about this drug.
if you end up doing it i would cut that tab in half man. people have overdosed from a tenstrip of this shit before, its not a particularly safe psychedelic. maybe someone with more experience combining SSRIs and 25i can chime in, but my spidey senses tell me you should take it easy with this combo.
25i is cool...its pretty much exactly like 2C-I to me. the fact that people put it on blotters is NOT COOL though. in an ideal world, nothing should be allowed to be laid on blotter other than LSD
also i dont think skipping your dose of effexor will really take away the danger of contraindication--plus that will most likely make you more anxious and uncomfortable. i would say just start with a low dose and work your way up, but im not sure if taking the full 1000ug is the best idea.
if you end up doing it i would cut that tab in half man. people have overdosed from a tenstrip of this shit before, its not a particularly safe psychedelic. maybe someone with more experience combining SSRIs and 25i can chime in, but my spidey senses tell me you should take it easy with this combo.
25i is cool...its pretty much exactly like 2C-I to me. the fact that people put it on blotters is NOT COOL though. in an ideal world, nothing should be allowed to be laid on blotter other than LSD
also i dont think skipping your dose of effexor will really take away the danger of contraindication--plus that will most likely make you more anxious and uncomfortable. i would say just start with a low dose and work your way up, but im not sure if taking the full 1000ug is the best idea.
Last edited:
bloodshed344
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No, stop effexor for at least a few weeks and THEN take 25I-nbome. Effexor and similar compounds are going to stop almost all effects you would get from 25I, it would be a total waste. Also effexor is poison for your mind and body, damages the memory and the sex drive (takes you hours to get off doesnt it?) I know from personal experience. Get that chemical lobotomy out of your brain, and once its completely gone try 25I.
oh and weight has nothing to do with psychedelic effects, however bigger people have more peripheral receptors in their body, so they are less likely to get physical side effects whilst getting the same mental side effects, However thats pure speculation, I do know for a fact that just because you're bigger doesnt mean youll need a bigger dose. I probably need a much bigger dose than you and I weigh 130 pounds.
oh and weight has nothing to do with psychedelic effects, however bigger people have more peripheral receptors in their body, so they are less likely to get physical side effects whilst getting the same mental side effects, However thats pure speculation, I do know for a fact that just because you're bigger doesnt mean youll need a bigger dose. I probably need a much bigger dose than you and I weigh 130 pounds.
infantannihilator
Bluelighter
Your brain is castrated at the moment. It will be a waste
bloodshed344
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Definitely stop using it. Have you noticed how hard it is to get off? If you're a male of course.
Also look up "effexor and memory problems" on Google that will turn you off of it relatively quickly.
Just remember that you don't need a chemical like that in your brain to make your life better, all you need is your inner will. Effexor is poison in my opinion, I took it for about a week before I decided I was done imbibing poison. It made me manic, too. and also, yes, I'm very sure it would waste it. At least wait a few weeks after discontinuing effexor to use 25I. Infact in my opinion I think use of SSRIs in your life will have an effect on your psychedelic trips for the rest of your life.
infantannihilator
Bluelighter
Honestly, bloodshed is spouting off side effects that are possible side effects. Not everyone who takes an SSRI will have trouble orgasming or other sides and so on and so forth.. you can google just about any symptom in relation to any drug and find a few hits. Google hallucinogens and HPPD or talk to someone like Magicduck. Obviously if you're on an SSRI there is a reason and you and/or your therapist deemed it beneficial for you.
Personally I was on prozak for a few months before I realized it wasn't for me. I had an amazing amount of insights and in some ways I really liked the person I became, I felt more like me if that even makes any sense. It was a very eye opening experience. However, I soon found myself unable to hold opinions or feelings about anything, even stuff I enjoyed, everything was meh, but I was happy at the same time. I just started not to care about anything and it was bad for me. Also the lack of being able to orgasm affected me, and the prozak infact made me even hornier than ever.. so this was a big problem. I was seeing girls left and right but I couldn't nut.. no thanks. I also ended up breaking out with pretty bad bacne and chestne, something I had never had in my life before and which I 100% associate with the prozac.
I don't know the exact science behind it, but basically the medication you are on targets receptors in the brain that the drug you want to take also targets, because of this the drugs will not effect you in the same way it would a normal person, and could even be bad for you. In a nutshell your SSRI fucks with the target that the drugs mechanism is tryin to do work on.
As said your weight has nothing to do with how the drug will affect you really, and in all seriousness you should start out with 500ug to gauge your reaction to the drug..
However as has been said, you really should consider getting off the SSRI if you really want to use substances like these.. Don't listen to all the horror stories about antidepressants online, make the decision for yourself. Are they working for you?
Personally.. I actually really liked the person I became on them.. its just the negatives became worse than the benefits. Life is always a balancing act my friend
Personally I was on prozak for a few months before I realized it wasn't for me. I had an amazing amount of insights and in some ways I really liked the person I became, I felt more like me if that even makes any sense. It was a very eye opening experience. However, I soon found myself unable to hold opinions or feelings about anything, even stuff I enjoyed, everything was meh, but I was happy at the same time. I just started not to care about anything and it was bad for me. Also the lack of being able to orgasm affected me, and the prozak infact made me even hornier than ever.. so this was a big problem. I was seeing girls left and right but I couldn't nut.. no thanks. I also ended up breaking out with pretty bad bacne and chestne, something I had never had in my life before and which I 100% associate with the prozac.
I don't know the exact science behind it, but basically the medication you are on targets receptors in the brain that the drug you want to take also targets, because of this the drugs will not effect you in the same way it would a normal person, and could even be bad for you. In a nutshell your SSRI fucks with the target that the drugs mechanism is tryin to do work on.
As said your weight has nothing to do with how the drug will affect you really, and in all seriousness you should start out with 500ug to gauge your reaction to the drug..
However as has been said, you really should consider getting off the SSRI if you really want to use substances like these.. Don't listen to all the horror stories about antidepressants online, make the decision for yourself. Are they working for you?
Personally.. I actually really liked the person I became on them.. its just the negatives became worse than the benefits. Life is always a balancing act my friend
cyberius
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Stopping anxiety medication to take psychedelics with a bad/unknown safety profile is a terrible idea! I'd say stop taking effexor for about a week or two, then try 25i-nbome. Perhaps even start with 25c-nbome instead, it's more approachable IMO
bloodshed344
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Well I'm not spouting off possible side effects, I'm talking about personal experience. Also in my opinion effexor is too manic to be considered anxiety medication.
infantannihilator
Bluelighter
Personal experience is just that though, a set of [side] effects that made themselves known through you
ChrisSoSwagged
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I would stop taking the Effexor for 5-7 days and since its your first time, I would cut that 1000ug hit in half. Take one half, wait to see what happens, and then take the other half if necessary. I've tripped many, many times and IME 1000 ug is a nice dose once you're acclimated. I hope this helps you out.