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Pharmacology Trans Women on Estradiol and Menstrual Cycle-Like Symptoms

This thread contains discussion about a Pharmacology-related topic

arrall

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I’ve been on estradiol for almost a year and injectables for about 6 months and have started experiencing menstrual cycle-like symptoms - for about a week I feel very bloated and tired. It also comes with an extremely low mood and some depression.

Have any other transfemmes on estradiol experienced this, and is anyone well versed in the medical literature familiar with documentation of this?
 
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