Opioids Tramadol withdrawal & Citalopram

[Dandal]

I am stopping tramadol after 2 years of almost constant high!, and since its cheaply & easily available without prescription where I am, I reached high doses (1100mg max) but never had an issue except the withdrawals when the source is cut which sucks!

I don't really regret it, I lost like 30kg without any effort and its been a nice, warm ride, but for some reason I have to quit very fast so I lowered the dose from 700mg day to 200mg and I am in the 4th day of quitting cold-turkey but its still getting worse, and I am having suicidal thoughts!

I read that tramadol's shitty withdrawals are related to its SNRI properties, and Citopram is an SNRI so do you think it would help? (its one of the few things available)

Also it seems that some people's livers converts tramadol (which is supposed to be a weak opioid) to a more potent opioid called O-Desmethyltramadol which is probably why I enjoyed it.

 

[ErgicMergic]

Citalopram is an SSRI, not an SNRI, Effexor is the closest compound to Tramadol's 5-HT releasing and NRI effects, but it is an SNRI, so it's not exactly the same. Effexor inhibits 5-HT reuptake, while Tramadol releases 5-HT like a weaker version of MDMA would.

I would use Tramadol to taper off of Tramadol. It would take care of the 5-HT releasing and NRI effects, and also the withdrawals from the O-Des. Don't decrease the dose that fast, what are you thinking? Tramadol is a dirty-as-shit drug in terms of how many receptors it acts on, you have so many different receptor dependencies that a slow taper is the best choice. I would reduce 25% from 700mg every week at the very most, considering you've been on it for 2 years.

And I doubt you have CYP2D6 polymorphism. If you did, the amount of O-Des felt off of 1100mg a day would be equal to about 330-340mg hydrocodone a day, which would have you feeling more than "suicidal thoughts." You simply felt the O-Des effects by taking asinine dosages of tram, easily enough to be fatal.

 

[Paulymorphone]

clonodine (doses of 0.1mg to 0.3mg) can help a lot with withdrawal

 

[ErgicMergic]

^ Clonidine can help with the opioid portion of the tramadol withdrawal, but the 5-HT and NE portions, NMDA antagonism portion, and acetylcholine portions of withdrawal are more complex that simply inducing sympatholysis and inhibiting fight or flight responses with clonidine.

A gram of tramadol a day is a hell of a habit considering how "dirty" of a drug tramadol, the OP needs to taper tram with tram, and not simply rely on basic opioid withdrawal aids.

 

[mind-explorer]

I've been on >1200 mg/day for two month and had not really severe withdrawals. I quited suddenly, and had experienced insomnia, lack of motivation and symptoms similiar to flu. Weed helped me a lot.
Also, they lasted 5-7 days.

 

[Dandal]

Citalopram is an SSRI, not an SNRI, Effexor is the closest compound to Tramadol's 5-HT releasing and NRI effects, but it is an SNRI, so it's not exactly the same. Effexor inhibits 5-HT reuptake, while Tramadol releases 5-HT like a weaker version of MDMA would.

I would use Tramadol to taper off of Tramadol. It would take care of the 5-HT releasing and NRI effects, and also the withdrawals from the O-Des. Don't decrease the dose that fast, what are you thinking? Tramadol is a dirty-as-shit drug in terms of how many receptors it acts on, you have so many different receptor dependencies that a slow taper is the best choice. I would reduce 25% from 700mg every week at the very most, considering you've been on it for 2 years.

And I doubt you have CYP2D6 polymorphism. If you did, the amount of O-Des felt off of 1100mg a day would be equal to about 330-340mg hydrocodone a day, which would have you feeling more than "suicidal thoughts." You simply felt the O-Des effects by taking asinine dosages of tram, easily enough to be fatal.

actually I would've loved to taper off slowly, but I have to move to a totally different country really soon for the first time and I know no body there except my employer so I can't just tell them about my addiction!

clonodine (doses of 0.1mg to 0.3mg) can help a lot with withdrawal

ok I'll look for it, hopefully it's not controlled.

^ Clonidine can help with the opioid portion of the tramadol withdrawal, but the 5-HT and NE portions, NMDA antagonism portion, and acetylcholine portions of withdrawal are more complex that simply inducing sympatholysis and inhibiting fight or flight responses with clonidine.

A gram of tramadol a day is a hell of a habit considering how "dirty" of a drug tramadol, the OP needs to taper tram with tram, and not simply rely on basic opioid withdrawal aids.

what about mixing it with Pregabalin? just got a pack of 150mg tablets and waiting for its effects.

I've been on >1200 mg/day for two month and had not really severe withdrawals. I quited suddenly, and had experienced insomnia, lack of motivation and symptoms similiar to flu. Weed helped me a lot.
Also, they lasted 5-7 days.

If I had Weed I wouldn't have got into this shit on the first place! a bit weed can send me 4 years into jail! and yeah those symptoms are part of what I am experiencing in addition to extreme fatigue, confusion, depression, brain zaps, dizziness, shaking and some other stuff.
The depression is so severe that I cried while watching an action movie when some people died!

Anyway, I guess the peak was yesterday, I felt a lot less aweful than yesterday when I woke up, I am using Carisoprodol to force myself into sleep.

 

[ErgicMergic]

Carisoprodol and Pregabalin are good for this purpose, just keep dosages of both therapeutic (under 400-600mg of Lyrica a day, and under 1050mg Carisoprodol/day), since large doses of these two drugs can actually cause seizures, which you are already at risk for when withdrawing from tram.

Oh, tramadol... Take too much, and you might seize. You keep taking too much and get hooked then try to kick, and you might seize yet again.