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  • Trip Reports Moderator: Cheshire_Kat

(Topiramate / 150mg) + (Pregabaline / 250mg) + (Tilidin 50mg) - Totally Unexpected

dopamimetic

Bluelighter
Joined
Mar 21, 2013
Messages
2,127
Location
abyss of sobriety
It was a sad evening and I was desperate to escape, looking for something ... easy. I mostly dislike alcohol in such moments due to its side effects, as I do the (at lease the more easily available) opiates, well.. if they are available ... benzodiazepines weren't here. Pregabalines were limited, but I had have some great fun with them, but limited to -very- huge and only the -very- first takes after long times of absence. Then my eyes caught that blister of topamax and I've googled a bit of their action, reading that they do seem to have some similar bits of Pregabaline, in that of potentiating GABAergic drugs and acting of some ion chnanels, being anti-epileptic ... well, playing with fire, but, knowing that even overdosing Pregabaline felt save and adding one or two Lorazepam, some mg's of Picamilon (a supplement made of GABA of nicain, that's able to cross the blood-brain-barrier and then dissolves into its components --> bringing even more Gaba into the game) I thought it won't be that bad. A could beer made the finish.

Lyrica 250mg + Topamax 150mg + Tilidine 50mg + Lorazepam 1mg + Pyrazolam 2mg + Picamilon ~25-35mg + 1-2 Beer(s) normal strength

So far to the ingredients. Don't remember much of the timeline. Also really underrated what comed next ... a full-blown-trip! Albeit I never felt anxious or in danger (even the opposite, I lay in bed, comfortably aware to what's going on, watching the (pseudo)hallucinations, feeling the warm euphoria - at one time, I thought, someone opened the door and watched if I am ok - even that I do absolutely know now that nowbody was at home that time! - but it was ok ... I chilled in bed, drank my beer, and eventually dozed off ... before that, I had amazingly closed eye visuals, moving, glowing fractals before a dark background, like never seen bevore.

Not multiple dosages of Pregabaline had been able do bring anything near of this (maybe the euphoria, but not the rest), multiplied dosages of Topiramate I do tolerate extraordinately well - some slight stimulation, some sedation when combined with a benzo, but nothing psychoactive -at all-.

So it has really to be a potentiation reation betweem the Pregebaline and the Topiramate that I'll explore further as soon as I'll have access again to both of them. Next time in a more controlled setting, without additional factors, in a more controlled setting. At the most Picamilon will be acceptable to boost the experience - what do you mean ...?

Anyone else experienced something similar ... ? This really made me wonder?

High dose (600 mg+ w/o tolerance) Pregabaline was one, if not the, most eurphoric experience I am able to remember clear headed. This one is maybe on par with that, even if more clouded. But if we could find a way to slow down tolerance building to the Pregabaline high, this would just be gorgeous for miserable times. And let me repeat, even if I had not used P. in small dosages (50-100mg/d for some weeks like I had), 250mg's would have done literally -nothing-.
 
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