Misc Took Too Much Phenibut

[Timland]

I've taken 10g doses of Phenibut before. I relate to the "something's off" its hard to put it into words, and is distinctively different than other GABAergics for me.

It makes me feel a sideays drunkenness for the first 24 hours and then I sleep, literally, 20-30 hours without waking up once when I lay down after I get a drunken insomnia for 24 hours. It is most definitely not pleasant. Then I wakeup sore from lack of REM and lack of body movement during unconsciousness [I assume].

Of all GABAergics, this is second only to barbiturates for GABAergic pharms that quite frankly I am extremely gingerly with.

But.. I'd say just wait it out. Don't drive anywhere. Relax, watch seasons of TV shows til you're able to sleep, and set aside at least 20 hours for sleep when you can, and maybe put a note for anyone who may physically attempt to wake you that you are sick and won't be rising for a prolonged period so they don't freak out.

NOTHING helped the fog headed wonderland effect that happened for a solid 24-30 hours.

 

[lolwhatzdrugs]

They have some other ones - valproic acid (Depakote) has that property in its repertoire and they have an obscure drug called vigabatrin (Sabril) that has the property as well. The class certainly seems small though.

Wasn't aware! I figured they'd cause seizures?


I'll check it out more.

 

[MagickalKat777]

Wasn't aware! I figured they'd cause seizures?


I'll check it out more.

Why would decreasing the levels of l-glutamate in the brain cause seizures? I would think it would do the opposite, especially when it comes to slowing catabolization of GABA.

Either way, there definitely seem to be a lot of side effects with vigabatrin and everyone knows how nasty valproic acid is so I never experimented with vigabatrin.

I can say that I tried tiagabine (Gabitril), a GABA reuptake inhibitor, and I didn't much care for the side effects either. It seemed to have a mild effect on my anxiety but that could have easily been placebo.

I haven't experimented with lemon balm outside of the Relax-All product that I posted the ingredients for. I'm interested in any information that you find.

 

[lolwhatzdrugs]

Why would decreasing the levels of l-glutamate in the brain cause seizures?

I thought we were talking about a drug that increases the metabolism of GABA? But looking back, it inhibits the breakdown to l-glutamate.


But looking around "Glutamic acid has been implicated in epileptic seizures. Microinjection of glutamic acid into neurons produces spontaneous depolarisations around one second apart, and this firing pattern is similar to what is known as paroxysmal depolarizing shift in epileptic attacks."


Which would decrease it, not increase it. Fuck I'm being dumb, and need some sleep! ARGghhh