Snövit-Rödvit
Greenlighter
- Joined
- Aug 5, 2024
- Messages
- 8
TI;dr Could anyone share their experience with using the mentioned substances or NAC to help reverse tolerance, and let me know if the amino acids can be taken together to achieve upregulation of NMDAr
Hi! Long time lurker first-time poster.
I understand that time is the best for a tolerance reset, but I am looking for ways to potentially speed up the process. I don’t have perma tolerance but it is rather high. I’d also like to enjoy pregabs again which has no effect after heavy ket use even after 3 weeks of cessation, but my main focus is ket.
I've read that Noopept agonizes NMDAr, so l'm wondering if it could be used to upregulate/ resensitize NMDA.
While I don't have access to sarcosine, I have read that glycine is also an NMDA agonist and have seen some positive reports. As for glutamine, it is also an NMDA agonist, so I was thinking of taking them both at the same time or cycling them every other day. Or is NAC a better substance for my goal?
I am aware that when taken together, these amino acids can lead to protein synthesis, but I'm not sure if this means they lose their NMDA action.
Additionally, my friend swears of racetams having a positive effect on tolerance by upregulating NMDA. However, I am confused about this since racetams are AMPAkines. And I can’t try his because he’s stopped using ket and in turn racetams.
Hi! Long time lurker first-time poster.
I understand that time is the best for a tolerance reset, but I am looking for ways to potentially speed up the process. I don’t have perma tolerance but it is rather high. I’d also like to enjoy pregabs again which has no effect after heavy ket use even after 3 weeks of cessation, but my main focus is ket.
I've read that Noopept agonizes NMDAr, so l'm wondering if it could be used to upregulate/ resensitize NMDA.
While I don't have access to sarcosine, I have read that glycine is also an NMDA agonist and have seen some positive reports. As for glutamine, it is also an NMDA agonist, so I was thinking of taking them both at the same time or cycling them every other day. Or is NAC a better substance for my goal?
I am aware that when taken together, these amino acids can lead to protein synthesis, but I'm not sure if this means they lose their NMDA action.
Additionally, my friend swears of racetams having a positive effect on tolerance by upregulating NMDA. However, I am confused about this since racetams are AMPAkines. And I can’t try his because he’s stopped using ket and in turn racetams.