THEY ARE REPLACING OUR ADHD MEDICATIONS WITH ANTIDEPRESSANTS WTF!?!?

[Cream Gravy?]

Well they aren't euphoric like stimulants can be (maybe some hypomania in some patients though). But there's a reason that they're used as a first-line against depression. They're generally safe and effective.



No, strattera is an NRI, and a DRI in the neocortex.

But... they aren’t. I’ve never gotten relief from SSRIs and on top of that they once caused me to have Serotinin Syndrome. I would NOT call that safe nor effective. Not to mention they block the action of psychedelics which ACTUALLY help with depression. My wife used to chastise me for not giving them an umpteenth chance; then I gave her some psilacetin and her depression went away for weeks. Now she’s a true believer. Now she doesn’t pressure me to go on SSRIs.

 

[FuckinAcidMan]

I am deeply suspicious of anyone who preaches the efficacy of SSRI's

 

[AlphaMethylPhenyl]

But... they aren’t. I’ve never gotten relief from SSRIs and on top of that they once caused me to have Serotinin Syndrome. I would NOT call that safe nor effective. Not to mention they block the action of psychedelics which ACTUALLY help with depression. My wife used to chastise me for not giving them an umpteenth chance; then I gave her some psilacetin and her depression went away for weeks. Now she’s a true believer. Now she doesn’t pressure me to go on SSRIs.

For you it seems. I'm talking about actual macro statistics.

I am deeply suspicious of anyone who preaches the efficacy of SSRI's

You make it sound like I'm a religious radical. All I said is that there is reason for them to be tried first. This is substantiated theory.

Stimulants on the other hand don;t produce euthymia, but an ephemeral euphoria. For real ADHD they tend to work. Not expecting a lot of agreement, especially on this site, so I'm not getting into it anymore.

 

[Cream Gravy?]

For you it seems. I'm talking about actual macro statistics.



You make it sound like I'm a religious radical. All I said is that there is reason for them to be tried first. This is substantiated theory.

Stimulants on the other hand don;t produce euthymia, but an ephemeral euphoria. For real ADHD they tend to work. Not expecting a lot of agreement, especially on this site, so I'm not getting into it anymore.

I mean, if they actually work for people, they can have 'em, I don't care. But I'm pretty fuckin' sick of psychiatrists who think the answer to all problems is the blocking of serotonin reuptake. It's pseudo-science. Prozac is 80% placebo effect.

 

[TheSacredTree]

I had a doctor like 4 years ago try to prescribe me Strattera with the intention of supplementing my Adderall with a second stimulant to synergize with and make it 3x stronger. I never tried it but my friend did and said it worked. I thought it was ridiculous and didn’t want to go with that plan at all.

 

[JoEhJoEh]

Just because it's no stimulant doesn't mean it works. I had Strattera years ago but quitted it because my libido was destroyed. But it worked with all the ADHD-Issues.

JJ

 

[Wilson Wilson]

I'm not sure why you think they're being 'replaced', as there's no evidence for that. It's standard practice in the UK to begin ADHD patients on atomoxetine (or even bupropion). If that doesn't work, then they try other meds. Seems like a reasonable, cautious strategy.

That is the NICE guideline yes. In practice most ADHD specialists use methylphenidate (usually in the form of Concerta) as the first line med though, which I'm guessing is simply because atomoxetine has a reputation for being ineffective. I think I saw a study where it only worked in like 20% of patients compared to 70-80% for stims. And it has SSRI-like side effects so yeah. Makes a lot more sense to have the effective drugs with fewer side effects as the first ones to try.

Amphetamine is more effective than methylphenidate for most patients as well, but I would guess MPH is first line due to it being less abusable.

When I got diagnosed with ADHD it went Concerta > Vyvanse > Dexedrine. Was never given any non-stim meds for ADHD. Docs tend to have a strong preference for time release medications though.

 

[CFC]

That is the NICE guideline yes. In practice most ADHD specialists use methylphenidate (usually in the form of Concerta) as the first line med though, which I'm guessing is simply because atomoxetine has a reputation for being ineffective. I think I saw a study where it only worked in like 20% of patients compared to 70-80% for stims. And it has SSRI-like side effects so yeah. Makes a lot more sense to have the effective drugs with fewer side effects as the first ones to try.

Amphetamine is more effective than methylphenidate for most patients as well, but I would guess MPH is first line due to it being less abusable.

When I got diagnosed with ADHD it went Concerta > Vyvanse > Dexedrine. Was never given any non-stim meds for ADHD. Docs tend to have a strong preference for time release medications though.

Funnily enough mine just put me straight on vyvanse, but most others I've spoken to tended to get either bupropion or atomoxetine first. I guess it depends on the provider. I bought atomoxetine myself many years ago and, like many, found it to be horrible lol.

 

[Wilson Wilson]

Funnily enough mine just put me straight on vyvanse, but most others I've spoken to tended to get either bupropion or atomoxetine first. I guess it depends on the provider. I bought atomoxetine myself many years ago and, like many, found it to be horrible lol.

I've actually never heard of bupropion being used for ADHD. On the NHS it's only used for smoking cessation and even then only rarely. Not approved as an antidepressant for some reason, which is a shame because it seems a lot better than SSRIs.

But yeah not actually surprised you got put straight on Vyvanse. UK docs tend to be fairly relaxed when it comes to stims particularly the time release ones. When my mate got diagnosed with ADHD a few years after me he was straight up given a choice of which stim he wanted. No fucking around!

 

[CFC]

I've actually never heard of bupropion being used for ADHD. On the NHS it's only used for smoking cessation and even then only rarely.

it can be prescribed for a number of reasons. i was put on it for depression for some time, but it caused way too much bruxism and insomnia to be useful

 

[Branggen]

True.. I mean I don't think anyone should see drug use as a matter of right or wrong. Drugs are tools. A lot of them are powerful and should be used with caution. But I think a lot of these doctors in California wanna put all the blame on Methamphetamine because of the few dozen tweakers that commit crimes but what about the ones that function like normal human beings because their ADHD is in check? And yeah alcohol is very legal and how many times do we see or hear on the news about how some fuck head who was drunk crashes and ends up hurting and sometimes killing a civilian or a family yet that piece of shit drunk fuck walks away with no scratches but just a DUI as a reminder to not do it again but they usually do cuz why not. It’s legal and you can buy it over the counter.
Our minds are not yet developed enough to fully utilize them to their full potential but some of us can meditate properly so shit I would be happy with my prescription Desoxyn and some GHB for my sleep apnea and I’ll be good to go. Guranfuckintee you I won’t commit any crimes or be an unlawful citizen because those drugs won’t effect me negatively unless I chose to let them. It’s people who have fucked this up for the rest of us.. and those bastards need to die already!

Pretty sure if you kill someone while DUI you get more than a DUI

 

[Wilson Wilson]

it can be prescribed for a number of reasons. i was put on it for depression for some time, but it caused way too much bruxism and insomnia to be useful

I should have said it's only approved for smoking cessation, sounds like docs script it off-label more commonly than I thought.

 

[Shady's Fox]

I think CBD can cure ADHD.