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Opioids The Opioid Withdrawal Megathread and FAQ

SavageHank said:
Hi,
I'm not sure where to post this, but I just want to get it down so I can hear some feedback. I've been addicted to Poppy Seed Tea for a while. (~5yrs on/off). I got clean from it cold turkey the first time, but that only lasted for maybe 2 years. I've quit suboxone CT at a high dose before (~8mg/day). I stupidly started suboxone during what would've been a relatively easy Roxy withdrawal. Quitting subs lead to Poppy seed tea (because it was "legal"). Knowing what I know now, I think PST is ridiculously hard to WD from. This time around, I've been using for about a year. My dose is pretty irrelevant, I think, because I have no idea how much Morphine/Codeine et al, I've been ingesting. I've been taking ~1.25 lbs. of strong seeds to make my daily dose.

So here is why I'm posting...it's time to stop again. I decided to meet with a Sub doc and tried to induce after 40 hours since my last dose. That lead to precipitated withdrawals...started at 4mg, then 8mg, then 12mg...and nothing. Crushed, I made a quick .90 lb batch of PST. (I only did 1 wash vs. my usual 3 washes). This basically eased the withdrawals and helped me get through the day and even sleep all night. I wasn't "fine". I was BRIGHT red and had hot flashes, but I could walk around, which I needed, because we were going away for the weekend on a camping trip. Being a husband and father, i had a lot to do...I couldn't just lay around and wait it out (not that that's any easier). The next day I actually felt OK when I woke up. I made the mistake of trying my suboxone again with similar results (though not quite as bad as the day before)...with no relief at all, I ended up taking 16mg throughout the day (the last 4mg once I noticed I wouldn't be sleeping). So this night, I had to get up and leave the camper with diarrhea about 4 or 5 times. I was actually glad to be getting some of the toxicity out of my intestines (as I assumed that's what lead to my precipitated withdrawals----the drugs lingering in my intestines without being "evacuated" enough in the 40 hours since my last dose). I drank a whole bottle of benadryl and a whole bunch of tylenol PM's etc., which didn't seem to do anything, but I did seem to maybe sleep for 2 hours from 4am-6am...Had to pack up and head home the next day (yesterday). With only 12mg of subs left, I dosed 4mg in the morning around 8am...and then another 4 around 11am....this time, around 38 hours after that PST dose (that I had hoped would not have mattered, but it did). Still no relief, I broke down AGAIN and took a .50lb of seeds to make 1 wash of tea. Rested for most of the day. I drank 4 beers throughout the afternoon/evening and still wasn't sure if I would sleep, so I took 6 tylenol pms (stupid move)...this made me snore and my wife thought that meant I dosed again because I didn't snore when we were camping...not sure why I didn't snore the 1st night camping (maybe the beer helps cause it)...

Okay, so today is Monday. The sub doc called to check on me. I told her what happened, and she promptly dropped me. he told me she would call in 2 weeks of 8mg subs as a "courtesy" and then I was on my own. (Fwiw, I called the doc after induction telling her about the precipitated withdrawal caused....she told me to up it to 12mg for that day). When I told her I had used 12mg avg. over the next 2 days, she dropped me without disucssion. Basically hung up on me, and told me to call back with my pharmacy phone number. This hurt. I was hoping she would work with me. My plan....my hope was that I could stabilize on 4mg of subs at induction and taper off over 2 weeks. When the induction didn't work, I didn't know what to do (they worked so well for pill wd's)....

So , here I am....about 22hours since that last .50lb dose off PST. I'm managing right now. luckily I can "work" from home...I have 4mg of subs left, and hopefully that doctor actually called in the 2wk script to my pharmacy. My thinking right now is to try taking Loperamide once the withdrawals start to really kick in again (probably before that to be honest, as they take a long time to kick in)...After that, I want to get to a point where I can get through a safe 4mg induction of Suboxone...I just have NO IDEA how long to wait...48hrs?, 72hrs? 7 days??? This shit is so ridiculous that I half way wish I would've just been using heroin so the Subs would have worked...

I'm looking for advice on what to do over the next couple of days. I had considered a taper plan with PST, but that will only prolong things and force me to keep lying to my wife. on top of this, my companies new fiscal year is just starting and I have to go to Vegas in 8 days, for 2 days of conferences (including meeting my new boss)....
..
Sorry for the looooooong post here. Mods please feel free to move this. I don't know where it should go. I am very interested and hopeful for any advice I can get from here. Thanks....
Click to expand...

I had a similar experience to this. I also use PST and got a hold of some subs a few weeks ago and tried to kick. I waited around 40 hours and dosed 4mg and it sent me straight into precipitated WD.. I read that you can take more sub every hour to get through the precipitated WD.. that is a load of B.S! I took like an entire 8mg that night and had the worst night of my life. I ended up dosing PST and am preparing for another detox. The best thing to do if you get PWD is stop taking sub and wait it out. I'm guessing we have to wait at least 72 hrs or until we have scored a 26 on the COWS worksheet. I found an awesome induction guide from Mr. Robert 325 online. Start of with real low doses of sub like 2mg. I will messsge you the link to his guide. I'm planning on trying Kratom this time around, at least until I feel safe enough to take the sub. PST is no joke man! The half life is super long. Good luck bud!
 
http://www.drugs.com/forum/featured-drugs/suboxone-subutex-therapy-50887.html
Here is an awesome guide for anyone trying to get off opiates using Suboxone. A quick taper is the safest way to avoid becoming addicted to the sub. You should also never need to take high doses. I used sub to quit oxy/dope before and I started off at 4mg and worked my way down to like .25MG. I then jumped off with pretty much no withdrawls. Best of luck!
 
I need help.
I am about 5 billion degrees . I'm sweaty, I feel sick. I want this roller coaster to end.
What I'm asking is if someone can help me set up a taper schedule to allow for as EASY taper as possible.
On Friday, I get my script. I will have 120 X 20mg oxy ER to work with. They are sustained release but I can cut them in halves and quarters if need be. I can also "come into" some perks or dilly if needed, or oxy 5.
Right now it feels like no matter how much I take I never feel good, it just stops me from feeling awful... For a few hours. My dose ranges but probably 200mg-250mg daily. Right now I only have perks . To give you an example of my tolerance, it takes about 35mg IR minimum to take away WD. 6-7 hours later they're back.
Any ideas?
 
I am currently only about 12 days off heroin, but I think I am done this time. I have quite many times before, but always knew in the back of my head I wasn't done. Sometimes I was off for months, but I have never felt like this about it. Finding the right anti depressant has made all the difference for me I think. Anyway. After I got through withdrawal, I had a few nights of cruel and teasing heroin dreams as normal, but on the third night of dreams I dreamt what has so far been my final heroin dream. I was too close to passing out to enjoy the high, which may not make sense to all users, but that is always how I felt about heroin: I had a sweet spot where I got lots of euphoria and could still function to some degree, but if I went beyond that I was too numb to even care I was feeling well, and I could almost feel how close I was to death and how I wasn't having a full experience. I dreamt I was too high like that, making a fool out of myself essentially, dumping the rice I was attempting to eat into my lap. Only for a split second did I wake up with the normal feeling of "yay I have heroin oh wait GOD no that wasn't real" and I quickly became happy it was just a dream, because I was acting so shamefully in front of important people, and because I didn't want to set my heroin withdrawal back and suffer more, I had done that too many times before and was sick of it. This is a preface, but that struck me as so different, the runny nose hadn't even gone away.
Maybe fixing my moods to some degree was the only factor that made this heroin withdrawal so different, but my attitude toward the experience was also completely different. So I want to share this, in case it could help anyone.
Going into it I focused on not being scared: the fear of of how bad I would soon be feeling is awful, and I am sure focusing on it too much just makes things worse. I was not successful, I was terrified, but I made sure to at least fight it as much as possible by staying busy. I made sure to physically exhaust myself as symptoms started on the first day not using, as I think the body high you would normally get from pushing yourself in exercise can help your body readjust, although obviously in withdrawal you cant expect it to feel good. Plus anything that might help you be able to get just even 10 minutes of sleep you wouldn't have otherwise becomes so precious when sick.
The next day the real suffering started. About 10 mg of lope to help just a little with the shits, a bit of DXM, and ashwagandha to help my body adjust, and an aubsurd amount of tums, but no expectation of overly significant help, this is the time to suffer. Soon the time when every moment is more bearable is approaching. Acceptance I deserve to suffer for some of the things Iv done while high and to stay that way. A growing sense of humor which came in flashes, seeing myself from above, vomiting while shiting on the toliet, what absurdly self defeating attempts to feel good could have resulted in this almost cartoonish picture of suffering? The fucking noises I am making.
Another day of it. Almost starting to feel something that's not physical, but emotional, actually caring about the regret a bit more deeply, and the realization that suffering is the human condition, so I am rejoining them by doing it in a way. Of course the first emotions allowed through after numbness are regret and sadness, but being able to feel these makes me human and are also pre requisites to feeling happy at some unknown future point.
The realization I can be away from the bathroom long enough to do something. Back to trying to exhaust myself as much as possible whenever stomach and guts allowed. Music to motivate myself. This was a turning point. For a moment, I felt something I liked without with heroin for the first time. It reminded me of what it was like to be able to be moved. Remembering when I used to drive myself on with a totally different kind of energy, a spiritual power. Feeling a crazy uncomfortable energy coming out of my lower back, somewhere around one of the bottom 4-5 vertebrae. Running hot water on that spot, trying to loosen up from there progressivly through the rest of my back. Doing so when walking, showering, when lying on my back and holding my legs together and rolling them around. Using spirit power as a mantra. Thinking the feeling of restless everything was actually a positive energy I could use but just had to readjust to feeling. Focusing on bring it out from my lower back when stretching and walking. Rediscovering music, having just one moment in the day where I almost felt happy, getting up and trying to start the day after no sleep again,what is this day 6 I have been up? Using the energy of punk songs and not the lizard like contentedness with whatever that heroin provided. Spirit power, knowing I will sleep some time soon,trying to exhaust myself to make it come sooner.
Since I'v quit I decided I was tricked when I forgot what it was like to feel emotions. I had a dream I believe to be about this where I would be walking and my whole environment around me would suddenly change from the interior of a house to an open beach scene, but I would know it was a hallucination and wait for it to pass before moving so I didn't like walk into a wall or something. Just spending a good day with my boyfriend is such a deeper happiness than the contentedness I used to trade everything for. I am so thankful, almost dumbfounded, he stayed with me through all of it.
 
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My name is Jessica, I am 27 years old and currently live in the WA State. Right now I am at my parent's house in Missouri. I am on day three of an 8-month addiction to oxycodone. I tried to withdraw last month but after two days I was right back on it. The symptoms were just too much for me to handle psychologically I guess. I have always been an addict, since the age of 15. I have smoked pot for over ten years, had a few years of alcohol addiction in my early twenties, (I haven't drank in years) I have done other drugs recreationally like benzo, mushrooms, excessive amounts of no-doze when I was in my teens. I was also thoroughly addicted to Tramadol two years ago. I never would have thought ten years later my life would be what it is now. I've lost so much in just under a year. I live with my boyfriend of three years, a cancer survivor who uses oxycodone and morphine on a daily basis. This is where my habit started. A 5 MG here a 5 MG there when I was having back pain due to two bulged discs. Then, of course, you need more to feel the same effect and eight months later I am riding a 90 MG daily habit. A person that used to pride themselves on having a fat bank account by diligent saving has under $100.00. All I cared about was when am I going to get my next pill. I am here at my parents house not by choice. My 20-year-old sister committed suicide on June 1st. I was high throughout the entire process begging by boyfriend for more and more before and during the funeral. He is my enabler and I am his. He left back to Seattle last Wednesday and left me with one 15 mg oxy and 150 mg morphine. I didn't find out until hours later. I suffered some sort of psychotic break knowing I was going to be going through withdraws. I contacted my other sister who lives close to my parents and she brought me over 12 5 MG oxycodone. Like the addict I am, I took all in one day even though I knew better and should have tapered like the last time I withdrew. Felt so dumb the next day. So here I am day three. Feeling so much better. The last two days have been pure hell. Thomas recipe has helped me. I have taken benzo and Ambien vitamin extra B6 and B12, gabapentin has also helped a bit. I am so so sick of oxy. I am scared to fly back to Seattle in two days. I am scared I will relapse again. I can't just take one. My mind just wants more and more. With my boyfriend still addicted and my boss also addicted, I am going back to a scary situation. I hope I am strong enough to say no. I can't afford it my body cannot tolerate another withdraw. I have basically laid in bed for the last two days sweating my ass off, cold as hell. sick to my stomach, runs, joint pain, coughing, sneezing, teary eyes, you name it. Oxycodone is the devil. Those little blue pills have ruined me. I guess I am just writing this to let people know you are not alone. There are people out there, you would not expect to be so thoroughly addicted to pain medication. I am ready to get my life back and the future is in my hands. I am looking for a sponser when I get back and I am going to attend some NA meetings. The threat of replase is too strong in my mind. I worry that I will not have the strength to say no to just one pill and then my habit starts all over again. I know I can do it. I just have to have will power and strength.
 
The problem with Robert325 taper is he uses the same rapid taper for anyone on sub whether they took it for two weeks or two years. He rushed people to get off it too fast and I think that probably led to many relapses. He had the right idea but seemed very arrogant and acted like he invented the suboxone taper when anyone can find the basic knowledge he would tell people by doing a search.

I'm sure he helped many people who were too stupid to do their own research but probably a lot of people got off sub too fast when they should take their time and go by how they feel, not because Robert said this is how it should be
 
I'm
Not familiar with Robert unless he's the one that another crappier site's people treat him like Jesus begging him for help.
I hear you on the one size fits all approach. I do think that it's not for everyone.
However, I've been on oxy for years. I've overused / abused it for years. I'm im the middle of a taper. It's a quick taper, but for me slow, going by 1 20mg pill every single day. I'm only a few days in and already on half the dose I was on when I started (was at 15x20mg )
All that to say that sometimes a long drawn out taper is more problematic than beneficial. I think for almost everyone , the best case is to taper the fastest you can without having WD.
Because every day it stretches on, it's tempting to take more than your taper schedule, and you're forced to think about and ration drugs, which we sucked at and that's why we're in this position in the first place.
I actually got one of those lock boxes from Kickstarter for $50 that you can set to anything and it stays locked until then. No override. I take out my dailies and lock up the rest. Or you could take out a aingle serving and lock up the rest , but I figure the more you open it the more chance u take more than needed. I would have def taken more if not for it.

Anyway going back to taper schedules, it's like with smoking, many people find it easier to just cold turkey than to get the willpower to taper.
With drugs I think most of us are self aware enough they would know whether a taper or CT would work better.
Now, to your say 10% of severe , long term addicts, who mostly inject, and opiates have become their entire life, and lifestyle has completely changed (I think the overwhelming majority of us are functional drug addicts) those people would likely fail with cold turkey OR a taper, unless they were in at least a 90day rehab.
These 10%ers if rehab isn't an option. Really should probably do MMT. At least it stabilizes them, gets them out of that lifestyle, and enables them to be part of society again. Then, after several years when they have things under control, then they could start a slow taper. A
Select number might elect to be lifers on MMT, which is still far better than the alternative.
 
You are correct doing a taper with opiates like oxy or heroin is impossible for most people, with a maintenance drug like suboxone or methadone a slow taper is almost always the correct way to go, maybe a small percentage of people can't do a taper but with suboxone it is a lot easier to lower your dose and not get tempted to take more, methadone might be harder but still probably easier to taper than trying to taper heroin.

Also you say the majority of us opiate users are functioning, I'd have to disagree, most start out functioning but most people who aren't taking meds for legit reasons will become disfunctioning users most of the time. It's sometimes a long process but most of us will get to that point. Most people who take opiates for any extended period are likely to struggle for many years.
 
jesshaley253 said:
My name is Jessica, I am 27 years old and currently live in the WA State. Right now I am at my parent's house in Missouri. I am on day three of an 8-month addiction to oxycodone. I tried to withdraw last month but after two days I was right back on it. The symptoms were just too much for me to handle psychologically I guess. I have always been an addict, since the age of 15. I have smoked pot for over ten years, had a few years of alcohol addiction in my early twenties, (I haven't drank in years) I have done other drugs recreationally like benzo, mushrooms, excessive amounts of no-doze when I was in my teens. I was also thoroughly addicted to Tramadol two years ago. I never would have thought ten years later my life would be what it is now. I've lost so much in just under a year. I live with my boyfriend of three years, a cancer survivor who uses oxycodone and morphine on a daily basis. This is where my habit started. A 5 MG here a 5 MG there when I was having back pain due to two bulged discs. Then, of course, you need more to feel the same effect and eight months later I am riding a 90 MG daily habit. A person that used to pride themselves on having a fat bank account by diligent saving has under $100.00. All I cared about was when am I going to get my next pill. I am here at my parents house not by choice. My 20-year-old sister committed suicide on June 1st. I was high throughout the entire process begging by boyfriend for more and more before and during the funeral. He is my enabler and I am his. He left back to Seattle last Wednesday and left me with one 15 mg oxy and 150 mg morphine. I didn't find out until hours later. I suffered some sort of psychotic break knowing I was going to be going through withdraws. I contacted my other sister who lives close to my parents and she brought me over 12 5 MG oxycodone. Like the addict I am, I took all in one day even though I knew better and should have tapered like the last time I withdrew. Felt so dumb the next day. So here I am day three. Feeling so much better. The last two days have been pure hell. Thomas recipe has helped me. I have taken benzo and Ambien vitamin extra B6 and B12, gabapentin has also helped a bit. I am so so sick of oxy. I am scared to fly back to Seattle in two days. I am scared I will relapse again. I can't just take one. My mind just wants more and more. With my boyfriend still addicted and my boss also addicted, I am going back to a scary situation. I hope I am strong enough to say no. I can't afford it my body cannot tolerate another withdraw. I have basically laid in bed for the last two days sweating my ass off, cold as hell. sick to my stomach, runs, joint pain, coughing, sneezing, teary eyes, you name it. Oxycodone is the devil. Those little blue pills have ruined me. I guess I am just writing this to let people know you are not alone. There are people out there, you would not expect to be so thoroughly addicted to pain medication. I am ready to get my life back and the future is in my hands. I am looking for a sponser when I get back and I am going to attend some NA meetings. The threat of replase is too strong in my mind. I worry that I will not have the strength to say no to just one pill and then my habit starts all over again. I know I can do it. I just have to have will power and strength.
Click to expand...

Do not go back to seattle. Stay with your parents and get better then get a new job or go to school wherever you are now. If you go back things will only get worse, you can get off relatively easy now or you have a lot more suffering in the years to come. Without knowing you I can say going back will 98% chance of falling back in.

Every withdrawal from now on gets worse than the previous. You had your fun with pills, from now on they have nothing left to offer you and the only thing that happens is tolerance goes up and euphoria goes down. Good luck, PM me if you want. From Vancouver here
 
Hey i get very bad restless leg and depression, dihareea and anxiety when coming off the opiate. Also if i got clean for a week and did a pill again just one night and moderate dose will that restart my withdrawl symptoms from the start like they were before. First post and almost would call it a test run to see if im acctivated... they messin around and slackin on dem emails boy :$
 
It won't reset them but it will extend the withdrawals if you are still feeling rough, wait til you are out of wd a few days if you want to dose one day and not feel full withdrawal effects
 
Jetthecaf said:
You are correct doing a taper with opiates like oxy or heroin is impossible for most people, with a maintenance drug like suboxone or methadone a slow taper is almost always the correct way to go, maybe a small percentage of people can't do a taper but with suboxone it is a lot easier to lower your dose and not get tempted to take more, methadone might be harder but still probably easier to taper than trying to taper heroin.

Also you say the majority of us opiate users are functioning, I'd have to disagree, most start out functioning but most people who aren't taking meds for legit reasons will become disfunctioning users most of the time. It's sometimes a long process but most of us will get to that point. Most people who take opiates for any extended period are likely to struggle for many years.
Click to expand...
Would u say the majority on BL are nonfunctional because that's what I meant :)
 
My doctors think I may be sensitive to pain and want me off opiates. 20mg Percocet a day can't be that bad if used with a healthy region. One doctor wants me to get Ketamine for eight hours IV. I don't know how to proceed. Any ideas?
 
I'm going thru wd right now
Have been for a week
I went on vacation to the Virgin Islands for two weeks after a 2-3 g habit of h. Im prescribed oxycodone 30mg but I took all 210 pills in a week ...I know
Tolerance of a rhino. I go home tomorrow but any recomendations for the next 22 hours ESPECIALLY for the flight?! OTC meds have not worked. I'm allergic to aspirin, nsaids, and clonidine. Kratom&tramadol do not help bc my tolerance is way too high. I feel like a dookie.
 
Aurora, you're in a pickle. Fake something at the hospital before your flight? Show them your bottle but say you flared at destination? If they balk say you just need a days worth.
Are you planning to stay off once you get home? You're almost at the end!
 
Fentanyl withdrawal

I'm not sure if this is correctly posted (right place, etc). Can anyone tell me how long you need to be without an opioid to have minimal tolerance? Have experienced withdrawal from patches previously, one of the worst things I have ever experienced. I was on 100mcg, 75, now 62, strangely, this time I seem to have missed the acute withdrawal phase, maybe because of the patches have problems sticking? Have not worn a patch for about 1 week but have used them buccally. Have not used any for 2 days but have had dreadful sweats. I really hate fentanyl and trying to go without anything BUT what is worse; pain or dependence?

If I went on bupe patches would this make my tolerance lower?

Is suicidal ideation common when withdrawing?
 
Fully sic said:
I'm not sure if this is correctly posted (right place, etc). Can anyone tell me how long you need to be without an opioid to have minimal tolerance? Have experienced withdrawal from patches previously, one of the worst things I have ever experienced. I was on 100mcg, 75, now 62, strangely, this time I seem to have missed the acute withdrawal phase, maybe because of the patches have problems sticking? Have not worn a patch for about 1 week but have used them buccally. Have not used any for 2 days but have had dreadful sweats. I really hate fentanyl and trying to go without anything BUT what is worse; pain or dependence?

If I went on bupe patches would this make my tolerance lower?

Is suicidal ideation common when withdrawing?
Click to expand...

It's individual how long it make take before tolerance has decreased to minimal. For some weeks does the trick, for others it takes a least 3-4 months.
If you don´t want to be depended to strong painkillers as fentanyl and you can manage to live with the pain, then you should do so. If the pain is debilitating, and there is no alternative methods to relieve the pain, then I suggest that you keep taking your prescribed medication.
The only one who can judge whether pain or dependence is worse, is yourself.
Switching to buprenorphine patches will lower tolerance once your body has sort of adapted to it.
Suicidal ideation and such negative thoughts is common when kicking the habit. It is generally just temporarily.
 
10 years and counting

So I had my first back surgery at 16 years old and my second at 18. My issues started 06 at age 14. I was eventually diagnosed with bulging discs, arthritis and degenerative disc disease is my lower back. First surgery they put rods and screws in my lower back (went thru my back), second one they went thru my stomach to replace one of the discs that was still moving around creating pain. The surgeon told me if I still experienced pain after that, that I will be one of the unlucky ones that will just "manage the pain" the rest of my life and that there was nothing else they could do. Of course I've been to all kinds of doctors, pain management Drs and I'm now almost 24 and been "managing" with my pain for 3 years on pain medication. I've tried smaller and larger doses of hydro, fentanyl patches, oxy, tramadol etc. nothing ever gets rid of the pain fully, but since my experience with oxy when withdrawals get was sooooo bad, I won't let myself go above norco. So my current prescription is 10/3.25 Norco 5 a day but I run out early every month and go thru a week of withdrawal before getting my next script. I hate doing this to myself but it's something that is almost impossible to Not do, due to my constant severe back pain. I can't fill for another 5 days or so, so I tried the Imodium thing to help with withdrawals (RLS, anxiety, nausea in the morning so far) because I have to work most of the days I'm without my meds. It seems to be working, this is my first day of Imodium use. I took 20mg around 2, and then 16 a few hours later. Will this help with sleep? I also have Valerian root which i don't know what dosage I should take, but I'll try anything OTC. I'm just trying to get thru the week at this point, until this happens again. I just feel like I need help and opinions on my lifelong battle I'm going to be fighting and figure out a way to make my meds last thru the whole month. Any help appreciated and I will answer any questions
 
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There is research that suggests a single high dose of bupe can be used to detox from short-acting opioids like heroin rather painlessly...do you think this method could also work with methadone?


Rapid heroin detoxification using a single high dose of buprenorphine.
To test the effect of 32 mg of buprenorphine on the withdrawal process from heroin, 10 street-heroin using subjects were given 32 mg of sublingual buprenorphine, following heroin abstinence of 24 hours. Withdrawal symptoms were monitored during the first few hours, and followed for six days after buprenorphine administration, after which naltrexone (50 mg) was introduced to prevent future heroin use. Nine subjects completed detoxification with negligible withdrawal symptoms and a smooth transition to naltrexone. One subject was excluded from the study due to methadone ingestion prior to experiment. These results strongly suggest that painless detoxification from heroin can be obtained by a single high dose of buprenorphine.

http://www.ncbi.nlm.nih.gov/pubmed/11476266

Abstract
Background: Heroin dependence is a raising problem.

Objective: To investigate the effect of a single dose of 120 mg of buprenorphine for the detoxification of heroin dependence.

Results: A single dose of 120 mg of buprenorphine is very useful for the treatment of heroin dependents.

Discussion: This study describes that one high dose of buprenorphine is beneficial for the management of heroin dependence. This finding is outstanding.

Conclusion: We concluded that a single high dose of buprenorphine may treat heroin withdrawal symptoms very well. This finding is a considerable addition to the literature of heroin detoxification

http://www.avensonline.org/wp-content/uploads/JAP-2330-2178-04-0023.pdf
 
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