Leprechaun
Bluelighter
" HAVE been researched have shown signs of neurotoxicity. "
Whats your source? Even the heavier psychedelic amphetamines show little sign of toxicity. Things like mescaline have no evident signs of neurological damage.
The only mechanism for indole and phenethylamine(non amphetamine) that I could find that could possible result in any permanent neurological changes would be through over excitation of glutamatergic receptors. I am not sure how that would involve 5-HT2 (psychedelic excitation).
The only well documented toxicity is on the stimulant psychedelics like MDA/MDMA and even then damage through recreational use, this is debatable and negligable so called damage.
http://www.maps.org/research/mdma/litupdates/overviews/04.02.html
http://thedea.org/neurotoxicity.html
http://apt.rcpsych.org/cgi/content/full/8/3/189
Whats your source? Even the heavier psychedelic amphetamines show little sign of toxicity. Things like mescaline have no evident signs of neurological damage.
The only mechanism for indole and phenethylamine(non amphetamine) that I could find that could possible result in any permanent neurological changes would be through over excitation of glutamatergic receptors. I am not sure how that would involve 5-HT2 (psychedelic excitation).
The only well documented toxicity is on the stimulant psychedelics like MDA/MDMA and even then damage through recreational use, this is debatable and negligable so called damage.
http://www.maps.org/research/mdma/litupdates/overviews/04.02.html
http://thedea.org/neurotoxicity.html
http://apt.rcpsych.org/cgi/content/full/8/3/189