Jabberwocky
Frumious Bandersnatch
shn()z said:I'm a little surprised to see the common (approaching universal) theme that redosing methylone is worthless. I've now gotten a few experiences under my belt, and I definitely feel it when I take a second (or even a third) booster dose. (I did take a fourth dose once, and that did indeed appear to have no effect.)
While the empathogenic quality is definitely lower than from the initial dose, it still feels good to take a supplemental dose about 90 minutes in. (I've found that an initial 250mg followed by 150mg an hour and a half later is a nice fit.) I feel an extension (or return) of the euphoria, nystagmus, etc.
Yet I see many people say that even a single booster dose has no effect whatsoever. I wonder if it has anything to do with drug cross-tolerance---I had not used MDMA for over 13 years before I tried methylone. (I'm only guessing that there must be cross-tolerance between MDMA and M1, since at least for me, they ring so many of the same neural bells.)
I think it is a little bit of a misrepresentation of the total public here on the PD forum. I would guess there is more redosing going on than is represented here. I do not think it is a cross-tolerance thing. Rather, I think the answer is in your post. Most here are after the empathogenic qualities of bk-MDMA, rather than the stimulated drug-like effects (btw, the nystagmus, jaw grinding, and other stimulated effects were the exact effects Shulgin was trying to synth OUT of MDMA).
In addition, there is good reason to think that it is very possible that redosing increases neurotoxicity (as this is the case with MDMA). Regardless, it is obvious that with most people's biochemistry, redosing carries more negatives than positives. It seems like with empathogens, one modest dose, all at once, is best if one is looking to minimize the comedown/long-term negative effects.
YMMV.