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The Old and Overgrown Methylone Thread (11-2002 to 2-2007)

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What was the setting? Methylone is very fickle, I took it three times and thought it was junk. Then on my fourth try (this time in optimal setting which was camping in the desert alone with my girlfriend) we had a beautiful, entactogenic experience. Preperation is key.
 
ambush, you might consider taking your remaining 150mg rectally when you use it again, because that should be the equivalent strength of about 200-225mg oral (estimated of course), which for sure should provide you with powerful effects. If you take 150mg orally next time, it'll do even less than your 160mg dosage unless some hidden factors heavily infleunce the expreiecne.
 
When I take methylone with my friends I can hardly notice the effects -- I'm just more talkative.
 
shn()z said:
Yes. Not severely, but I noticed some mild chills and gooseflesh lasting into the following morning.

Ive found it to have TFMPP type reactions when ive taken it myself but only at higher doses like 200 - 400mg+ (over a period of time) on the comedown. But I like it and always will :)
 
morninggloryseed said:
Quiet, subdued setting, or loud party? Methylone seems best in a quiet, dark setting (best at night) with one or two at most.

quiet and dark...
as i said, my other friend found it totally amazing.
 
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Jamshyd said:
This morning I woke up with lots of anxiety, and zero motivation to do anything. Not to mention horrific depression.. and get this: I had only one thing in mind... take more fucking methylone. The craving is is worse than meth. It is worse than coke. I have never felt so complled to redose on anything as much as with this one.
It does have very potent (and sweet, for those of us who appreciate) effects on dopamine. I really wouldn't recommend M1 to those who've tried dopamine boosters or reuptake inhibitors and disliked the effects, or who couldn't deal with the comedown and day-after results. M1 can cause intense stimulation, boost sex drive and result in jonesing/cravings. Just be aware/prepared and realize it's not all serotonin with this one.

IMO, solitary types like myself may actually enjoy it more (altho it unfortunately had that "first time magical, all-others-ho-hum" effect in my case and always feels way too expensive for what it offers... just like coke).
Delsyd said:
Does redosing work with methylone?
It does for me, but mostly the stimulant effects (which I've always enjoyed about as much as entact/empathogenic ones, guess that puts me in the small minority here). Hope nobody's offended, but redosing via rectal admin can result in slow/gradual absorption and ridiculously long rolls. Seems like 15 hours is about the limit for me tho, after that the high turns dark and paranoia, anxiety and hallucinations start becoming an issue.
 
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MDPVagrant said:
It does have very potent (and sweet, for those of us who appreciate) effects on dopamine. I really wouldn't recommend M1 to those who've tried dopamine boosters or reuptake inhibitors and disliked the effects, or who couldn't deal with the comedown and day-after results. M1 can cause intense stimulation, boost sex drive and result in jonesing/cravings. Just be aware/prepared and realize it's not all serotonin with this one.

IMO, solitary types like myself may actually enjoy it more (altho it unfortunately had that "first time magical, all-others-ho-hum" effect in my case).

It can be used as a party drug, but the dosages required to maintain its stimulant effects practically make coke a cheaper proposition.


I think you are confusing M1 with MDPV. Methylone isn't much of a stimulant (unless you take obscene dosages or boost), and few report comedowns.

The sole benefit might be M1's legality, but there are other legal stimulants that are cheaper.

I'm pretty damn sure you are confused because M1 is a fantastic material in its own right, its not a stimulants...it is an entactogen, and its worth is based far more on the fact that it is legal in some areas. You seem very confused, and based on your name, I am positive you are thinking we are discussing MDPV.
 
morninggloryseed said:
I think you are confusing M1 with MDPV. Methylone isn't much of a stimulant (unless you take obscene dosages or boost), and few report comedowns.
I'm not confusing the two. First off, yes to both the so-called exceptions you listed above... I think a lot more people use it that way than you suspect.

Re: the second point, probably true when it's dosed once and no redoses are involved (I wouldn't really know), but medium to long 'runs' can result in a fairly mean crash. The longest I ever stretched a methylone run was about 20 hours, and believe me the aftermath was unpleasant. Not quite the soul-killer coke or meth can be, but pretty nasty.
I'm pretty damn sure you are confused
Nope, I'm just not a "typical" Bluelighter by any stretch of the imagination. I like entactogens occasionally (although IMO methylone pales compared to MDA/MDMA), but straight-up stimulants even more.

I do think M1 fits into both categories, but the real question is whether it can truly satisfy either empath/entactogen fans or tweakers. Unfortunately, the first time was the only time I thought it was worth the money. MDPV is cheap enough that its flaws can be excused... M1 is not.
 
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MDPVagrant said:
Nope, I'm just not a "typical" Bluelighter by any stretch of the imagination. I like entactogens occasionally (although IMO methylone pales compared to MDA/MDMA), but straight-up stimulants even more.
Uumm, and what exactly is a "typical bluelighter"?

RE: your comment on my post... I'm really not sure what to make of what you're trying to get across. I never mentioned dopamine or serotonin, although methylone still has most affinity for Serotonin transporters, and to a lesser degree for the others, so I'm not sure what you mean by it being "dopamine and not all serotonin". If you are comparing it to MDMA, then MDMA has significant dopaminergic action as well.

And don't worry, I actually do appreciate pure stimulants (especially Amphetamine)... and I actually appreciate it a bit too much (I can never use them in moderation). I cannot see myself enjoying methylone stimulation though, not because it is stimulating, but because the stimulation it gives is neither useful nor euphoric. It reminds me more of caffeine-overdose stimulation than amp./coke stimulation.
 
I actually enjoy the methylone stimulation, to be honest. Of course I enjoy the entactogen aspect of it even more, but I always end up redosing with it because I also enjoy the stimulation. My reaction to various druvs has changed quite a bit over the last year, and I used to really fear the methylone comedown and stimulating plaeatu. However, I've grown to enjoy it, and now the comedown is no longer scary to me. Although it does compulse me to take more to a fiendish extent. This is why I can never keep methylone around for more than a few days.

I don't find itat all like caffeine overstimulation, which I despise with a passion. Lucky me, I guess. ;)
 
Methylone is about equally potent to MDMA at dopamine and norepinephren receptors, but 1/3 as potent at 5-HT receptors.

Methcathinone, the benzylic ketone analog of methamphetamine (MA), and methylone, the benzylic ketone analog of 3,4-methylenedioxymethamphetamine (MDMA), were synthesized and tested for their abilities to inhibit monoamine uptake in vitro. Methcathinone and methylone were threefold less potent than MA or MDMA at inhibiting [3H]5-HT uptake into human platelets, with IC50's of 31.4 ± 7.3 mM and 5.8 ± 0.7 mM, respectively. In C6 glial cells stably expressing the rat dopamine transporter, methcathinone and methylone were similar in potency to MA and MDMA, with IC50's for [3H]DA uptake of 0.36 ± 0.06 mM and 0.82 ± 0.17 mM, respectively. Methcathinone and methylone were also similar in potency to MA and MDMA in C6 cells expressing the human norepinephrine transporter, with IC50's for [3H]NE accumulation of 0.51 ± 0.10 mM and 1.2 ± 0.1 mM, respectively. The benzylic ketone moiety of methcathinone and methylone had a large (tenfold) negative impact on the abilities of these drugs to inhibit the vesicular monoamine transporter (VMAT2) compared to MA and MDMA. In VMAT2-containing bovine chromaffin granules, the IC50's for [3H]5-HT uptake were 103 ± 15 mM for methcathinone and 125 ± 16 mM for methylone. These results indicate that methcathinone and methylone are potent and selective inhibitors of plasma membrane catecholamine reuptake transporters, with more modest effects at the serotonin reuptake transporter. These drugs are essentially inactive at the vesicular monoamine transporter.

http://www.mdma.net/methylone/catechol.html

Taking into account the fact that most methylone users take close to double the dose in mg as they would with MDMA, one can extrapolate that they are causing close to 2/3 the 5-HT activity and twice the catecholamine activity with methylone compared to MDMA.
 
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MDPVagrant said:
Nope, I'm just not a "typical" Bluelighter by any stretch of the imagination. .

Sadly I see taking experimental drugs to the extreme...past excessive and straight into just plain stupid...is pretty typical around here. It seems those who respect their health (and I cannot believe anyone who does such a "20 hour" run has much respect for their health) and rides these things carefully are not the majority anymore...unless there are a LOT of lurkers.
 
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I just tried methylone for the first time. That was pretty funny. It doesn't last long enough, I even felt bad sometimes during the trip (on 200mg), all I felt like doing was to play a multiplayer videogame, I felt connected to others and so good because I was with them. It was very pleasant to play, my skills were higher (per opposition, MDMA descreases my skills). I was having funny conversations and even a deep one with someone. They were many discusions about drugs for some reason. It seems like many gamers do drugs. Methylone is fun... I also found it good for introspection. If you have no one to be around, which make one feel bad, take a sheet and a pencil and start talking, exchanging with yourself. It made me felt awesome. Am not really impress, but this stuff is definitly good. It makes me feel like am on amphetamines but on a lesser level. I was doing really good moves in the game, I didn't had to concentrate much. For me, it's just an experience, this compound is not really my thing and I feel I could get addicted easily. It feels so good... I tried 300 mg today and this time I really felt it, while on 200 mg it was rather subtile. After two hours, I start feeling weird, a little bad and want to take some more. Took an extra 100 mg and another 120 mg extra 2 hours later. I know it isn't bright but I felt bad... I hate MDMA, amphetamines and avoid them for that reason. Oh, and it costs so much, you have 5 doses of 200 mg in a gram while you have 55 doses of 18 mg of 2C-E for almost the same price. Well, that my little contribution to the big and dandy Methylone thread %)

I just did an hour of meditation after taking an extra 300 mg. Methylone and meditation is very pleasant and profound. Since it's a empathogen (love drug, correct me if am wrong) I thought about singing mantras like "love" or "friendship" "I love myself" to fill myself with love, all my body, I imagined I was glowing, made of love. I wonder if it can really boost such a drug. That was one profound meditation. I feel great... I also have a question, does some of you get CEV visuals on this one? I just had some intense visuals during my meditation, I would see things just like I see them in reality, I saw shadow people, I saw myself, I could even see my room even if it was dark and my eyes were closed... strangest thing is I would see my office in the wrong place. Never had such particular visuals. When I went to bed last night, closing my eyes, I would see complete landscapes and other things like objects, places I have seen, people etc. to a point I didn't know I was in my bed for brief moments. That was pleasant. I dunno if it's because of psychedelics but sometimes when am laying down on my bed, eye closed, I can't seem to figure if it's either morning, afternoon, evening or the night. It's so bizarre...

edit: I would like to add something about methylone: don't do what I did (i.e. taking 1000 mg over the course of 2 two days). I have found myself feeling very bad the next day, the other one crying and crying and crying and once again today, to a lesser degree and even having more or less intense suicidal thoughts (without planning to do it). As a pseudo-psychonaute, it's a drug I will avoid in the future.
 
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I tried M1 for the first time in the not to distant past couple of hours and I have to say that it was enjoyable. I always start low, always: 60mg and an empty stomach. I was surprised I felt anything at 60mg from all the reports (VictorB??? mentions a 50mg somewhere on like pg 1 of this thread).

The experience was very mild, but undeniably present. Felt good to just sit and talk to my GF and play guitar. I've been just begun to study classical guitar and I have been having issue with my playing sounding mechanical: finding it hard to express the emotion intrinsic to the piece.

With the aid of Methylone I was able to make it through that tough area. I could feel my guitar vibrate up through my chest, I could feel the gentle beauty in the music that I was playing. It was so easy to just relax and be a part of that beauty.

Talking to the GF was similar in that as we talked the vibration seemed to eminate from the chest/heart area.

Any 'ol way, I was never much into MDMA as depression is an issue with me and my nervous system. Needless to say, I have a healthy fear of methylone. It felt so good at 60mg that I will surely try it at MGS's recommended low of 175mg, with that being the extent of M1's relation with my world.
 
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