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  • BDD Moderators: Keif’ Richards | negrogesic

The Official Tramadol Discussion Thread

I just got a tram script. A small one, but decent enough. I had never had them before. I took 175 mg today and no doubt does it feel like a 'real' opiate. I read through a lot of people thoughts on it before taking any and wasn't expecting much. However, I'm pleasantly surprised about how nice they are. I do also have kpins, so I may take one tomorrow in addition. Gracias por todo.
AND:
To add: I took these pills at 9:50 am this morning at work. Went from a bit clearminded in the euphoric sense (if that makes sense to anyone), then a bit flighty (in a good way), talkative, then very mellow, and around 3pm I began getting very very mellow and started to nod. I don't recommend any hardcore working out during the comedown. I ran 4 miles on a treadmill and could very well have collapsed. Weight is definitely an issue when it comes to dosing (and obviously tolerance). I took 175 mg, have a 16 BMI (so I'm a small girl), and take opiates habitually.
 
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Be careful with the trams. It is the best work drug ever. If you have a shitty job, and you take trams at work then run out, work will be terrible. That's actually an understatement. Also, note that it takes longer to get hooked on tramadol than plain ol opiates, but once you're hooked, you're on 3 drugs in one. The holy trinity of painkillers.
 
So i was gonna steal my dogs medicine because it is prescribed to tramadol, but... after reading about the withdrawals i couldn't bring myself to put my little dog thru that.

So I went to scoop 20 valium today and they turned out to be tramadol.. I still jumped on them anyway because they were cheap (under a dollar each). I just took 5 so I'm interested to see how they compare to stronger more prevalent opiates.
 
wrong

delphinen said:
As sarbanes said before, large doses of Tramadol (like 500mg, I know, I know, risk of seizures), first gives you a very very nice euphoria from the very powerful SSRI effects, until the drug becomes O-Desmethyl in the liver .....The M1 metabolite is eliminated by metabolism in the kidneys. PAPAVER

500mg Tramadol, 6mg Alprazolam, 24mg Bromazepam, 50mg Diazepam, a good brand multivitamin while keeping you hydratated (A,B,C,D,E, etc. vitamins, Zinc, Magnesium, Electrolites, etc.) will achieve in some people one of the best highs of their life. I also recommend a little food (but just a little) before taking the pills.....In the interest of HARM REDUCTION this is stupid. No one regardless of their tolerance should attempt this combo it is retarded. It can lead to serotonin syndrome. This is a recipe for those who believe in purifying the species and eliminating retard procreation. PAPAVER

Also, ultram is not a SSRI nor even an MAOI. Although the O-desmethyl tramadol or M1 metabolite has shown some affinity to inhibit reputake of norepinephrine and serotonin. This does not classify it as a SSRI nor does it behave in this fashion. Racemic tramadol inhibits the neuronal reuptake of norepinephrine (NE) and serotonin (5-HT) equally, but the enantiomers differ in their selectivities for the two reuptake sites. The (R)-(+) enantiomer is 5-fold more potent in inhibiting 5-HT than NE reuptake, whereas the (S)-(–) enantiomer is about 5- to 10-fold more potent than the (R)-(+) enantiomer in inhibiting neuronal NE reuptake. Individually, the inhibitory activities of the two enantiomers at monoamine reuptake sites are probably insufficient to account for the antinociceptive and analgesic potency and efficacy of tramadol. Thus it’s more active as a MAO than SSRI. But not active enough to classify as such.PAPAVER.

The formation of the active metabolite, M1, is mediated by CYP2D6. Approximately 7% of the population has reduced
activity of the CYP2D6 isoenzyme of cytochrome P-450. This is why effects of tramadol and the m1 metabolite vary across users. Some are more efficient metabolizers than others.
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Wondering about tramadol

In the past I've always been a huge Tramadol lover, it always got me super high without issues and was one of my favorite opiates. I even got hooked on them for a while and when I came off it was the worst depression I've ever had combined with opiate w/ds. Anyways, more recently I've had a pretty expensive addiction for 6 months to ultra high potency kratom extracts which I needed to take every 4-8 hours to avoid w/d's. I have since come off of the kratom extracts, only for a few days now (feel great, no more w/d), but I have taken 300mg tramadol yesterday and felt practically nothing, 400mg today and still no opiate effects. I used to get super high on this stuff all the time. That website that someone posted earlier said that Sertraline could reduce the effects of Tramadol and I just came off of a small 50mg per day regimen (1 day before I got the trams) of Sertraline which is a very low dose and I even forgot to take it on some days. I'm wondering if Tramadol is not having the same effects because of the SSRI that I was on or if it's because I had an addiction to much stronger opiates recently. I really hope that if I stop taking trams for a few days now that I'm off the stronger opiates then I'll be able to get high off tramadol again. I know this is a crappy and jumbled post, but what do you guys think? Is it the SSRI or the fact that I've done stronger opiates recently? Will I be able to get high on tram again? Even though I just came off the kratom extracts I know that my tolerance is very low in comparison (15mg oxy would get me pretty high) and it seems like the Tramadol should be working but it's not which makes me wonder if it's the Sertraline.
 
I know it's kind of long, but did anyone get a chance to read my previous post? I'm really curious as to whether it's the SSRI still in my system rendering the tramadol useless or if it's because I had a stronger opiate addiction until recently (even though I know my tolerance is very low right now)? I hope the tram magically starts working like it used to.
 
It could be both, but it's most likely that what you're experiencing is simply tolerance. If you want to get anything out of tramadol, you need to stick to it, and not do stronger pain meds - when you go back, tramadol will have lost some of the magic. If you want your tolerance to go down, you need to stay off all pains for more than a couple of days (try a couple of weeks).
 
Is Tramadol considered a Narcotic? I saw on certain websites that it is a Narcotic-like drug. Does this mean it is not a narcotic?
 
bjv07 said:
Is Tramadol considered a Narcotic? I saw on certain websites that it is a Narcotic-like drug. Does this mean it is not a narcotic?
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Its weird, in some states it is considered a controlled substance and is considered a narcotic, but in most states its considered "narcotic like" and it isnt controlled (like my state) =D
 
I am unaware of it being controlled anywhere though it is proposed. Read the DEA's page.

The horrendeously missused term narcotic was originally defined as a derivitive of opium and semi or fully synthetics. Nowadays it is used as a perjorative to define and "bad" drug.

Ultram is a synthetic stripped-down piperidine analog of Codeine and, as such, is an opioid.
Remember there is a differience between opiod and opiate.
 
prhighmalrage said:
I know it's kind of long, but did anyone get a chance to read my previous post? I'm really curious as to whether it's the SSRI still in my system rendering the tramadol useless or if it's because I had a stronger opiate addiction until recently (even though I know my tolerance is very low right now)? I hope the tram magically starts working like it used to.
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The SSRI is my bet
 
i got a refill for 90 but pharm want refill for another week i can understand that for hydros and such but didnt think they were that strict on tramadol
 
Oh yes they will be. The DEA has listed it as a drug of concern due to its rise in popularity in abuse. It is on the watch list google DEA Drugs of concern. I always liked that my enemy publishes its plans of attack :)

However as of now due to its loose scheduling you can get online without any prior presc. and shipped overnight for 50 bucks for 90 of them. Not bad
 
okay, so i was just about to do 50mg or so of adderall when i remembered, "oh shit, i took 150mg of tramadol earlier", so i decided id get on bluelight.. its been about 14 hours since i took it, but i definately feel something, like, ive been kind of nauseous and tired the past few hours. anyway, i just wanted to know if you guys think taking the adderall would be safe.

thanks in advance
 
Tsukasa said:
^ Yea, it feels like i'm rolling on tramadol sometimes, but it isn't as good or rather uncompareable to pure MDMA in my opinion.
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for a time i did tramadol quite regularly because i got the same effect on large doses of tramadol i would get on mild doses of mdma; stimulation, feelings of well being, reduced inhibitions, eye wiggles, spontaneous laughing, music sounds fantastic and best of all I've never had that gurning i get from E.

I did it so often that i eventually HAD to take 200mg in the morning just to be able to get out of bed, and then another 200mg at lunch time or i would get the worst lethargy and knee aches. Like my knees felt like they were breaking down at the joints.
 
The Conscience said:
okay, so i was just about to do 50mg or so of adderall when i remembered, "oh shit, i took 150mg of tramadol earlier", so i decided id get on bluelight.. its been about 14 hours since i took it, but i definately feel something, like, ive been kind of nauseous and tired the past few hours. anyway, i just wanted to know if you guys think taking the adderall would be safe.

thanks in advance
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Suspect you know whether or not it was a good idea by now, but I'd say probably not the best even if you had a great time. Adderall is one of the (over 300) drugs on the list of drug interactions cosidered a "major" risk. It can cause Serotonin Syndrome sometimes and you really don't want that to happen. It happened to me not so long ago and I kinda wish it hadn't either cos it was probably the worst experience of my life :|

You'll probably be okay this time as it's been so long and severe SS is pretty rare anyway but I really wouldn't combine tram with any stims or psyches. If you get unlucky enough to get SS then I can assure you you won't be risking it again either and would advise everyone to do the same. You can get away with it plenty of times but it really can and does happen so I wouldn't make it a regular event ;)
 
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Well I've only started doing tramadols recently and I like them, they deal with this back pain I've been having a give me a nice buzz AND i can still do whatever i gotta do during the day, work or whatever. However, I am concerned about wding, if I wd bad will weed help?
 
DelusionalLDN said:
Well I've only started doing tramadols recently and I like them, they deal with this back pain I've been having a give me a nice buzz AND i can still do whatever i gotta do during the day, work or whatever. However, I am concerned about wding, if I wd bad will weed help?
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Personally, weed has always exacerbated what ever feeling i've had. That means if i was tired it makes me more tired, if i was happy it made me more happy, if i was anxious it made me more anxious. This being said, about ten years ago i had a really bad addiction to oxycodone. When ever i would smoke weed i would instantly begin to experience WDs. If i was already WDing it would become way more intense. This is however subjective, drugs effect everyone differently.
 
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