The Neuroscience and Pharmacology Quick Question Thread

[izo]

What does N-propylamphetamine feel like? Dosage?

someone here on bl had it years ago, i think it was bluedolphin...

 

[Fertile]

*NOTE* Before posting, convert the structure to a SMILES string and run it through Pubchem - https://pubchem.ncbi.nlm.nih.gov

It also shows SIMILER structures and compounds which your material is a substructure of. Pubchem provides REFERENCE.

It's also worth reading Shulgin's work. The ONLY place a halogen goes onto a PEA is at the para position.

 

[Rectify]

https://opsin.ch.cam.ac.uk/opsin/1-phenyl-2-aminopropane.png

 

[izo]

can anybody source some of this?

Unobtainium - Wikipedia

en.wikipedia.org

dumb joke, i know.

 

[izo]

I just read that antisense peptids show interesting effects and also often also active at the same target as the sense peptides. Does anybody knows more about this?

A review about them, didn’t read it yet:

Antisense peptides: a critical mini-review - PubMed

Antisense peptides are defined as those generated from the non-coding strand of DNA, and represent a peptide analog to antisense RNA technologies. Peptides generated from both parallel and anti-parallel readings of the non-coding strand of DNA have displayed biological activity, although...

pubmed.ncbi.nlm.nih.gov

 

[izo]

Can someone point me to why indole is most reactive on the 3 position?

 

[AlsoTapered]

Can someone point me to why indole is most reactive on the 3 position?

Library Genesis

libgen.li

Nucleophilicity of Indole Derivatives:  Activating and Deactivating Effects Based on Proton Affinities and Electron Density Properties
Nicolás Otero, Marcos Mandado, and Ricardo A. Mosquera
View Author Information
Cite this: J. Phys. Chem. A 2007, 111, 25, 5557–5562
Publication Date:June 1, 2007