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The LYRICA (pregabalin) Mega Thread

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Alot of doctors that seem stubborn when it comes to prescribing meds, even when the patient seems to know that he or she needs it, are recieving incentives from certain pharm companies to prescribe their brands of meds. Incentives such as trips to hawaii and shit. If you were to go into their office you would prob notice coffee cup on their desk with the name of the bullshit meds they just prescribed you. as well as note pads with the logo and a pen in his pocket with the name of the bunk pills.
Anyone that has sat at a doctors office lobby for over an hour has noticed the pharmacutical reps. comming to and fro from the office. You can tell its them by the suitcase on wheels that they always carry full of samples.
And then you have the doctors that wont prescribe opiate based drugs because they are afraid to offend the great Baboonga or whatever invisible man in the sky they worship.
 
homeydontplaythat said:
i cant afford an online source. i have medicaid.

all i want is to try it and see if it helps. it seems it would be overwhelmingly useful if it does. even if i just take it on a prn basis when i dont feel so hot it would be fucking awesome.

neurontin? i dont get how she thinks that would be better than lyrica. she is probably going off what experience she has with like 4 dif patients whereas im going off of what several hundred people have experienced via the internet. cock shit balls.
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Neurotin gives me a terrible case of the shits......I wonder if it has the same affects on other people?
 
yeah, the relationship between reps and drs is FUCKEd. my father is an MD and i know for a fact most of the shit dr's know about drugs is from what the rep fucking told them. for real. so biased. doing research on trials and then REAL life experiences by the patient is far more valuable information.

i have an extreme grandiosity issue with drs though. i am a drug nerd, started reading the PDR at 14. i DO know more about the pharmacological aspects of the meds than they do. every time i hear them explain what they think of a med i get SO FUCKING ANGRY inside. i know they are being fed by the rep and the limited patient base they have. i know my body and brain better, i KNOW what works for me and what i want to try. they always ALWAAAAAAAAAAYS script shit that a company is pushing and promising a vacation.

my entire family went to the don cesar resort on behalf of CIBA GIEGY in the early 90s. any dr under 50 is going to avoid ANYTHING scheduled like the plauge as well. they have been trained to choose non scheduled meds as to avoid lawsuit. they are scared to shit (and thats an understatement) of anyone getting addicted and malpractice claims related. if anyone diverted their meds the dr would be fucked. the DEA does check in on them. the whole game is fucked, which is why my father sold his pratice. the insurance and pharm co's RUN shit, the drs get nickled and dimed. its so fucked.

anyway, im still riding the pregabalin wave, split a bottle of wine with my girl and im fucked up. not much, like im lucid but i feel the synergy for sizure.

aight, bedtime. damn im hungry from this lyrica and booze.
 
I'm curious what you guys find different between neurontin and lyrica, because neurontin has a higher rating on askapatient.com.

I know lyrica was made to be more potent, but is it really more potent?

When I take neurontin I always get this numb feeling that comes over my entire body, and it seems to depress my CNS a lot too, because I can stand perfectly straight w/out moving a limb even a fraction of an inch. It allows me to be as still as a statue, while obliterating anxiety.

I see you guys like lyrica better, which I can get, but which one has worse wds? I'd prefer not to have any more physical addictions and am stopping the neurontin in a few days (after only taking it for a week). I was gonna get more but am worried about wds. Does neurontin have bad wds?
 
dude, if you actually have anxiety that interferes with your life, dont stop taking it. if you were just trying it, then go for it.

i havent taken neurontin. well i snorted it once in a halfway house, i think it calmed me a bit.

askpatient.com aye? have you noticed that on a lot of those sites its really neurotic housewives. i dont listen to anything people say on yahoo answers and such. southpark was correct when they deemed 1/4 of the US officially RETARDED.
 
homeydontplaythat said:
have you noticed that on a lot of those sites its really neurotic housewives. i dont listen to anything people say on yahoo answers and such. southpark was correct when they deemed 1/4 of the US officially RETARDED.
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agree... :\

well hmm Gabapentin seems an interesting substance too. Why do you hate it ? I'm gonna do my research about it..
 
its the same thing as lyrica. just more potent so it has less side effects and you dont need as many mg's. just like lexapro and celexa.

however, the chemical structures are unrelated...so its kinda weird.
 
Oh shit... so Neurontin is stronger than lyrica? Ok well that would make sense. Because I was honestly wondering how the hell lyrica could be any stronger after my last week on neurontin. If I take 900mg I get high as kite, and feel like I'm on a moderate mdma roll. I can punch myself in the chest and not feel a thing, it gives me energy, and seems to better as obliterating anxiety than xanax (it also makes me more talkative than anything I've ever took before which I like).
On xanax I can still feel anxiety, on neurontin I can hear a train coming and my heart won't skip a beat. I'm taking it for after opiate wds, for the anxiety mainly. So maybe I'll stay on it for another week or 2. I just don't wanna get to the point where I have a crazy high tolerance + an addiction. I have no problem with taking breaks in between.

And yeh homey I do actually notice the crazy housewives that was pretty fucking funny cause I hadn't thought about it.
A lot of them don't even seem to be using the medication at hand, all they do is complain about their husband whos on it, their daughter, their mother, and a lot of them do come off neurotic just like you said.
I still think yahoo answers is a bit worse though in that respect.

Ok well I guess I'll go take a couple neurontin now. Just got done with my day and wanna try and relax now.
 
man, this thread has become my second home.

i have some questions with lyrica:

is the weight gain pretty significant? is it from appetite and actually eating feeling more pleasurable(noticed both) or a combo of that and fluid retention/edema?

the sexual side effects suck. i cant get fully hard and couldnt come at all. anyone experience this, does it go away?

as far as tolerance, how fast does it build up and can you just take a break for a week or lower the dose? i read in a medical journal that you need 1 month of abstinence to go back to baseline. oh, i took 300mg in 2 sep doses and was buzzed. did the same today and no buzz. anxiolytic properties are still superb, but not intoxication/euphoria. wtf?

as far as half life, it is only 6 hrs...so how does this shit last all day? by 24 hrs there should only be like 6% in your system, yet i could feel it even when i woke up.

the carcinogenic/teratogenic effects scare the shit out of me. skin lesions??? wtf, basically skin cancer, right? on rxlist.com it said decreased sperm count, mutation of sperm, and fucking birth defects just from the father taking it even BEFORE conception. yeah, they havent tested it in humans but i would assume if it happens to a rat it would happen to a human. hope this isnt the new thalidomide.

any information is appreciated.
 
Weight gain, I have an increase appetite when I take it. But not as much as when I took antidepressant (remeron). And yea, eating is more pleasurable. For me I've got a little stomach and i'm a bit underweight, I dont liked to eat much. But now with lyrica it doesnt bother me anymore to eat big quantities.

About sexual side, I experimented only once what you describe. But usually no problems.

And for sure it doesnt stay for 24hrs. maybe it's still on your system but you don't feel the anxiolytic/nerve painkiller effect. For me it stay about 7-8hrs.

by the way I've never had buzz at 150mg dose. This is therapeutic dosage, so I dont think you will get any buzz, or maybe the few first times only. Only at 300mg I can reach a buzz.

I was thinking about tolerance. Maybe I can switch to Neurontin ( wich is another molecule ) to break my tolerance back to baseline without suffer from lyrica wd and still have neuralgic painkiller effect ?
 
you can read my reply in trip reports, altough my apetite increased since using lyrica i actualy lost weight , i wonder if there are more people on the board that lost weight instead of gaining.

on a random note , anybody else noticed that while on lyrica its hard or rare to yawn ?
 
man, this drug is so weird. i took 300mg the first day and was actually high. like a nice buzz. took the same amount the next day and didnt get any rec. effects!!! the anxiolytic effects are awesome and dont mitigate at all, but the 3rd (today) i took 450 and still no rec effects. so i just took another 300mg cause its friday and i want to get a little fucked up.

is it possible for tolerance to go up this fucking fast! i mean wtf? it really boggles my mind. hope this extra 300 does something, ill have taken a total of 700mg today. i mean cmon!
 
another thing, ive found that IV use does NOTHING over oral. i think PO may even be better. the BA is 90% but i was thinking the onset would be way faster than the normal 2hrs ive experienced with oral dosing. that has not been the case though. again, boggled is the word of the day. along with the letters f u c and k. thanks for watching kids!!
 
Yeh absolutely /\
Anything that effects gaba usually does that (not the post you just snuck in the one before it). I noticed the same thing too with neurontin. The first day I felt pretty good at 300mg, next day took 600mg to get the same effect. Next day did 900mg. At that point I took 2 days to clear my system and was able to get an effect at 300mg, but still weaker than the first time. Then back up to 600mg, and took 900mg again last night. And now today I'm not taking any.

All and all I love neurontin for what it does, but its obviously just another addicting drug thats only gonna wind up adding more bs to my life. I'm in a process of breaking addictions right now, not building them. So because of that I'm not taking anymore neurontin. I see myself 2 weeks from now taking up to 2000mg and I'm sure even that won't do what 300mg did the first time.
Its not like I didn't completely expect it... so I don't really care either way.
 
anyone devised a regimen in order to be able to still get high off it? its too good for me to take everyday if that means eventually it will poop out. ill gladly take breaks to preserve the effects. help a brotha out!
 
yeh if you are able to do 3 days on 3 days off that works fine for me with other GABA type pills.
It kept my tolerance low on xanax, same as phenibut too. On neurontin I know I could do the same thing, but it gets pointless because the 3 days I'm off I notice signs of psychological addiction getting worse. I think about it, and lose motivation waiting for when I can take it again. I personally don't like the dependency aspect.

But if you want, I would up your dose 300mg every day, for 3 days, than drop off for 3 days. If you only drop off for 1 or 2 its just not gonna be like it was befoer. But 3 days is usually enough for those receptors to get close enough back to normal. And you may want to just start at 600mg. It seems you only really get high off 300mg the first time.

So do:
600mg
900mg
1200mg
OFF
OFF
OFF
then repeat.

Thats generally what I've done in the past with other drugs too. Increase the dose for those 3 days and always make sure that time on = time off.
 
dude, thanks for the regimen. incredibly valuable info. the fact you have experience makes it WAAAAAAAAAAAAAAAAAAAAY more credible than the bullshit studies and shit the pharm co releases. who THE FUCK do you think provides funding for those studies? huh? of course they are going to be biased.

that is why i became addicted to alt.drugs.hard and now bluelight; first hand experience always trumps some shit you read in a book written by a dude that has never even ingested the drug.
 
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