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The LYRICA (pregabalin) Mega Thread

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J.T. said:
anyone know anything about this drug causing either decreased fertility or possible birth defects when used by potential fathers?
Click to expand...

From the Pfizer Lyrica insert I received with my medication:

"Animal studies have shown that pregabalin, the active ingredient in LYRICA, made male animals less fertile and caused sperm to change. Also, in animal studies, birth defects were seen in the offspring (babies) of male animals treated with pregabalin. It is not known if these problems can happen in people who take LYRICA."

~ vaya
 
how long have you been on it again dim? I may just take it for 5 months so I know the benzo withdrawal is gone and then wean off. also are you able to orgasm and achieve an erection? Im assuming you just mean you diont have very much of a sex drive.
 
Has anyone had any experience cycling both pregabalin and gabapentin on and off to maintain a consistent state of effectiveness?

I take Neurontin 800qid and always find I need far more after the second week, ending up having to go around a 7-10 days without the drug. Interestingly enough, the tolerance seems to drop as rapidly as it develops, and after I obtain the next months cache it seems to have completely reset itself.

Since both the drugs are fairly cross-tolerant, I'm hypothesizing Lyrica to be a suitable cycler 1/3 of the month to Neurontins 2/3.

Good luck explaining all of this to my psych.
 
thouart_that said:
Has anyone had any experience cycling both pregabalin and gabapentin on and off to maintain a consistent state of effectiveness?

I take Neurontin 800qid and always find I need far more after the second week, ending up having to go around a 7-10 days without the drug. Interestingly enough, the tolerance seems to drop as rapidly as it develops, and after I obtain the next months cache it seems to have completely reset itself.

Since both the drugs are fairly cross-tolerant, I'm hypothesizing Lyrica to be a suitable cycler 1/3 of the month to Neurontins 2/3.

Good luck explaining all of this to my psych.
Click to expand...

from what I've been told lyrica is just a much more potent neurontin. I am no doctor and don't really know but I would imagine taking lyrica would raise your tolerance making the neurontin less effective. Again, im not sure. What are you using it for?
 
i never experienced blurry vision so i cant tell

but to be short .

lyrica made me less driven to have sex in the long run , but i didn't noticed any orgasms or erections problems over time.
 
what about concentration? I noticed that I had trouble concentrating but that could be benzo withdrawal. Also, I took kratom so im kind of out of it.
 
^from my understanding, they are both gaba analogs and work nearly identically but Lyrica is considerably more potent mg:mg. I don't think there is any substantial difference in their mechanisms of action.
 
duneplanet said:
what about concentration? I noticed that I had trouble concentrating but that could be benzo withdrawal. Also, I took kratom so im kind of out of it.
Click to expand...

concentrating has become more difficult for me , my mind want to go all kinds of directions.
But my Focus seems to imp somewhat.
biggest downside for me is that my short time memory is a mess on lyrica.
 
I upped my dose and didn't sleep at all last night. hmm. and i slept for like 3 minutes this morning but it was like a half awake dream state. I hate that.
 
drug_FUCKED said:
Pifer begs to differ
Click to expand...

Are you saying that to me? I kind of doubt it seeing as how pfizer was responsible for both drugs. The patent was long gone on gabapentin and it was increasingly being used off label so they saw the potential of getting a new GABA analogue on the market that won't have a generic alternative for a number of years.

Pharmaceutical companies do this all the time. AstraZeneca did this when Prilosec's patent ran out so they marketed its S-entantiomer as Nexium and even branded it the "new" purple pill (after prilosec was marketed as 'the purple pill') and to cap it off, told prilosec patients in ads to ask their doctors for nexium despite no demonstrable increase in efficacy corresponding to the increased price.
 
yeah lyrica is more potent but apparently with the same mechanism. at an equivalent dose pregabalin will usually have less side effects than gabapentin
 
im so wasted on lyrica right now. feeling great listening to my favourite music. ive got work in the morning and im sure i will still be intoxicated tomorrow. shit!
 
I have taken about ten 75mg pills of Lyrica in about a six hour period(I haven't gotten high in months, don't judge me).
And I'm telling you, it's great.
Sure, you can't pay as much attention as you can on other drugs,
and it makes typing and spelling REALLY FUCKING HARD. YOU HAVE TO PROOF READ EVERY FUCKING THING.
But I'm a wallflower, to say the least, and this shit makes me dance.
Like.
The world is awesome,
I'm awesome.
You're awesome.
And so is your mom (INBEDLASTNIGHT!!OSHIT).
The effects of it, at least for me, were the exact opposite of what it's supposed to do. I feel like I'm on Adderall of Ritalin or something.
It's really great.
DO ET, FAGGOT.
 
OMG, I have to post this. And I am not being "haha" to anyone, but I just quit taking opiates. And let me tell you, I love my opiates. My other true love next to my husband. So I was going thru major dt's, I IV everything. Yes a new junkie on the prowl. But I decided to stop, so I got my Lyrica, and let me tell you, this shit took away every withdrawal I had. I feel no pain. But when I tried to IV it, it gelled up in the thing and got stuck. Guess you can't cook it. But I read that you can IV it. Just don't cook it?
I love Lyrica, and the high is wonderful, and the sleep is the shit. Can't get enough of it....
 
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