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The LYRICA (pregabalin) Mega Thread

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no not really i felt pretty sober prior to taking the BRs and drinking. Also i hadnt smoked in over 2 weeks which might have added to it. Also my lyrica experience was very different than the ones described. I just felt very sedated, could barely move but felt awesome. This lasted for about 5 hours.
 
^ Just because you didn't feel the effects of it anymore doesn't mean it wasn't still in your system able to cause havoc. The break from marijuana smoking probably added to it too.
 
After using Lyrica for about a year (maybe more, can't remember) I've had enough chances to experiment. If taken with some other euphoriant like an opiate (high dose codeine / fent / tramadol is all I have experience with) it can be extremely euphoric but will numb some of the aspects of the opiates.

One of my favourite cocktails is 600-750mg Lyrica, 400-500mg codeine (I had quite a tolerance so it's a lowish dose for me - will probably feel stronger now) and 4-5 really good HBWR seeds, enough to make you see patterns in textures without concentrating, but not too much that the walls start melting. Not too psychedelic or inciteful but extremely euphoric if anything. I take Cardura and Prexium to counteract the increase in bl pressure from the LSA. I don't do it often because I can feel the vascular constriction properties of HBWR - I have an undiagnosed problem with bl pressure fluctuations in both directions (kidneys+heart perfect - stupid ass docs don't know WTF) it goes from too low 80/50 to ST3 to hypertensive crisis 250/150 (only in hospital - never been higher than 200/110 at home). Any ways, the Lyrica + opiate is to modify the stimulating body load from the HBWR from uncomfortable to something extremely enjoyable. You feel like you're floating on clouds if you close your eyes - I can't imagine taking HBWR by itself. Give it a try if you have used all the ingredients before and take a smaller dose of opiate than usual, increase as required.

Most I've taken is 1,500mg which kept me awake, was stimulating - I had taken large doses of Midazolam for the past few days, in the order of 80mg / day for 5 days which is about 6x the max dose. After stopping, that I night I got that feeling of cold, shock and panic about nothing. I realized that maybe I might be experiencing some sort of panic attack or w/d symptom from taking so much Midaz. and abruptly stopping, it had happened the previous time I did it - I was using so much because I was so desperate to get to sleep the past few days (practically bed ridden with pain - chronic insomniac) and the Midazolam was working for 2-3 hours at a time and then I'd wake up in pain. Also I know Lyrica has been trialled in alcohol + benzo w/d so I decided to increase the amount.

I swear the Lyrica + "Midazollamed after-party" made me trip, I saw extremely vivid CEVs - Midazolam is known to do that if you take continuously and stop, Lyrica does so too at high doses, together they were a GABA psychedelic experience - if someone can explain that? Dreaming while you're awake - I felt like I was in a dream the whole time. I watched the movie Alexander on TV and well, you know how psychs or weed make movies more intense? Same goes for this combo - except I eventually didn't know WTF was going on. Just watching pictures, closing my eyes periodically to "see" the sound. I had to use my laptop to check out the plot afterwards. The colours were blurred and it was very difficult to recognize who was who, even though I have a large TV set running from a clear digital source (at first I thought it was the TV and started messing with it like a retard). The Lyrica helps with the paranoia of the Midaz w/d but it's not really a nice experience because you still feel a bit crappy. Maybe 0.5mg Xanax or Clonazepam would go down well with that.

The long term side effects of chronic use are low levels of concentration, impaired cognitive abilities (my spelling has gone to shit - getting better as the dose drops), lack of motivation, lack of drive, loss of vocab. I'm keen to get off it so I can get on with my life without having a chemical impair my thinking everyday. It's a major impairment - now I know how some of the dumber guys at school must have felt. Although I can still churn out source code like a machine, if push comes to shove - I'm just not as inciteful in the boardroom - or I struggle to phrase my sentences, which previously had almost perfect grammar and diverse vocab - obviously this is where your intellect is important in securing clients. The worst thing is forgetting what went on in important meetings or getting a project from the boss and totally forgetting absolutely everything he said about it - worse if you start arguing with him and tell him he's mad :)

I will be using amps for my next big meeting with clients who will bring in a lot of money - wish it could be modafinil but it's diffcult to get in my situation. My docs all pass the buck because they all think it's almost exactly like adderall / ritalin / desoxyn / dexedrine and has the same abuse potential.

So watch out for long term side effects - OFF TOPIC: I'd hate to be taking other psychoactive anti-convulsant meds. My uncle recently was misdiagnosed with epilepsy and he spent a whole night staring at the fire because he was seeing weird patterns and fractals (lol). He hated it. His epilepsy turned out to be bl pressure meds messing with his white blood cells. BACK OT:

It's cool to take every now and then - and a total GODSEND for neuralgia. I had to take 3600mg x 3 Neurontin to get the same effect (ie no pain in my dropped foot). Otherwise it took the maximum amount allowable of IV morphine once hourly in ICU just to settle it - it felt worse than my badly shattered hip. 2 months afterwards it went into full blown neuralgia, which meant no amount of opiates did anything. The only things that worked were weed, amphetamines/methcathinone/MDMA (made the pain much worse the next day), Lyrica and Neurontin.
 
Just another varying perspective. Lyrica is quite shitty:

1) It is very expensive, insurance or not. Shit, $50 a bottle w/ insurance, has to equal $10+ a pill streetwise right?

2) It is what I call a "head med," like shitty muscle relaxers, amitripaline, etc., it messes w/ my mind when I don't want it to.

3) Very little recreational value FOR ME. (And others as we've seen).

4) BUT, I've heard that it works medical wonders for all kinds of people and symptoms for those that can afford to take it.

Overall - DOUBLE YUCK!
 
Damn. I took 1500 mgs 5 hours ago.

I had to take 50 mgs Seroquel to slow the shit down. But I am still awake and enjoying music and doing things. Everything seems more interesting and I cannot feel bad feelings.

I have some tremors and motor hyperactivity. But quetiapine eased that a bit. I have no anxiety about possible convulsion. But why I am shaking if this is anti-epilectic drug?

I am so fucking HIGH still. Euphoria has gone down but I have energy for good and I don't even need to smoke a cigarette. Slight visual disturbances but they are minor. My heart feels to be racing too.
 
you were shaking because you took way more than you needed to. there are side effects from taking to much of a drug you know?

lyrica will get you high in much lower dosage people. it takes up to 2 1/2 hours to kick in if you have food in your stomach. i see people saying "well i waited an hour and decided to take twice as much cuz i wasnt feeling it yet" it does not work like that. it takes a little while to kick in but can be felt well into the next day as ^^ just said.

just relax and give it some time.
 
*If someone has posted this synergistic reality of Lyrica + Methadone then ignore what im about to say unuless you want to hear my experience with it.

The synergistic properties b/t methadone and benzos (esp xanax/klonopin/ativan) are amazing and both of those drugs create a whole new high.

That synergistic effect also happens b/t the top above mentions drugs Lyrica/Meth. The first time i took lyrica right after 100mg of methadone i took 3 150mg pills and it was definitly too much. Too paraphrase JASONCREST It was exactly like he said, the loss of cooridination, feeling drunk, double vision, nausea, couldnt walk straight at all, and eventually vomiting and then passing out.

Next time out learned my less took 1 150mg pill didnt do much so took two a total of 300mg and that with methadone was much better much less drunken feeling and more euphoric feeling.


In conclusion ive taken it a bunch of times since then. Its def not the meth or opiates and benzo combo but its a combo somewhat parrallel to that and with the right dose it creates a nice relaxing euphoric effect. The drug alone...not that great, just like benzos alone (just great for anxiety which i have).

But besides taking my benzo script and methadone clinic im proud to say ive been "clean" for about 2 years
 
I used to love lyric. I had the 150mg's.
First times i'd take 3-4 and it would feel reminiscent of a light e buzz.

then I took 8 one day. It was hell. I kept falling down, i fell down my stairs face first. I fell and smacked my forheard on the concrete walk outside. my brain felt like it was spinning. My body was weightless.

And then I decided to calm myself with a shot or two.

long story short ended up in the drunktank after the cops found me passed out, standing up, leaning against a bank.

Ever since that time whenever i take lyric i get a horrible feeling and just want it to end.
 
Just got my very expensive lyrica downed 3 x 150mg first time.
Had some clonazepam as well. Wonder what taking gabapentin with it will be like.
well i hope this drug helps me with my benzos leg pain withdrawals symptoms.
 
I just having bupe, smoking cones with it at 600mg of lyricaLand of coarse i tapering down so i had some clonazepam as well. I weird feeling tripping out paranoid at bit. Feel the taste of high does gabapentin. Some GHB like effects, sedating, i feel a bit wishy washy bit spun out and brain dead spaced out. (could be a lot of cones i had had a break some smoking for a bit then just started blazing again last few days)

I reckon this drug would be great for quitting GHB/GBL and alike.
I restores a lot of normality and functional different angle thinking.
I can see some people would have some nausea i can feel like a sea sickness
 
I very relaxed but very spun out could be the 50+ cones i have had.
At this rate i will go through the box quickly.
Least i not craving opiates or GHB.

Pregabalin
MIMS Abbreviated Prescribing Information
Section: 3(g) Anticonvulsants
Consumer Medicine Information: Available
Uses/Indications: GABA analogue, anticonvulsant, analgesic. Partial seizures +/- secondary generalisation (adjunct), neuropathic pain in adults

Precautions: Renal impairment; haemodialysis; CHF; diabetes; high dose; prolonged use (neuropathic pain); galactose intolerance, Lapp lactase deficiency, glucose/ galactose malabsorption (should not be used); elderly > 65 yrs; pregnancy, lactation, children < 18 yrs

Adverse Reactions: CNS effects incl dizziness, somnolence, confusion, loss of consciousness, mental impairment; visual disturbance incl blurred vision; fatigue; weight gain; ataxia; tremor; abnormal gait; dysarthria; oedema; GI upset; dry mouth; withdrawal symptoms; CHF; elevated CK; decr libido; paraesthesia; psychiatric effects incl euphoria, hallucination, depression; hypersensitivity incl angioedema (discontinue); pancreatitis, rhabdomyolysis, renal failure (rare); others, see full PI

Drug Interactions: Oxycodone; other CNS depressants; lorazepam, ethanol (poss)

That oxycodone interaction is interesting and i wonder why only lorazepam interacts....hmmmm

Pregabalin is an analogue of the neurotransmitter gamma-aminobutyric acid (GABA). It has analgesic and anticonvulsant activity.

Pharmacology. Mechanism of action. In vitro studies show that pregabalin binds to an auxiliary subunit (alpha2-delta protein) of voltage gated calcium channels in the central nervous system, potently displacing 3H-gabapentin. Two lines of evidence indicate that binding of pregabalin to the alpha2-delta site is required for analgesic and anticonvulsant activity in animal models: (1) studies with the inactive R-enantiomer and other structural derivatives of pregabalin and (2) studies of pregabalin in mutant mice with defective drug binding to the alpha2-delta protein. In addition, pregabalin reduces the release of several neurotransmitters, including glutamate, noradrenaline and substance P. The significance of these effects for the clinical pharmacology of pregabalin is not known.

Pregabalin does not show affinity for receptor sites or alter responses associated with the action of several common drugs for treating seizures or pain. Pregabalin does not interact with either GABAA or GABAB receptors; it is not converted metabolically into GABA or a GABA agonist; it is not an inhibitor of acute GABA uptake or degradation.

Pregabalin prevents pain related behaviours in animal models of neuropathic and postsurgical pain, including hyperalgesia and allodynia.

Pregabalin is also active in animal models of seizures, including maximal electroshock tonic extensor seizures in mice or rats, threshold clonic seizures from pentylenetetrazol, behavioural and electrographic seizures in hippocampal kindled rats and tonic and clonic seizures in DBA/2 audiogenic mice. Pregabalin does not reduce the incidence of spontaneous absence seizures in genetic absence epilepsy in rats from Strasbourg (GAERS).
 
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I just parachuted 2000 mgs of pregabalin powder. In two hours I'll see how fucked up I am. I have huge tolerance though
 
ive been prescribed lyrica for a few months now, and it definately does work for me recreationally, and it does wonders for my nerve pain, but for some reason im not compelled to abuse it, which is unlike me cause im the type of person who always chases a high when drugs are available. i guess since its so expensive that i feel i should take it as prescribed so it helps me rather than blowing 100$ a month just to get high. ill take 150 mg's or 300 mg's before bed, and i wake up still feeling the effects and gives me good analgesia during the day which i like

anyways, i get my refill tomorrow, and i had like 10 pills leftover cause some nights i forget to take my dose, so i took 8. im hoping to get good CEV's cause i tripped on acid for the first time a week ago and i fell in love with psychadelic experiences

i know ill still feel the full dose tomorrow and i have school so i hope i can still maintain. i have a feeling im gonna have a good night tonight
 
awww man musics the shit

fuckin eargasms! haha

i think im coming up on it. im in a good mood, and more social. ive been talking to alot of old friends on AIM. typing is alot harder though, especially with one hand. probably in an hour im gonna lay in bed and enjoy the CEV's )i hope i actually get some) . if i wake up tomorrow and am not satisfied with my high, i have 4 more i can take

theyre the 150 mg caps by the way
 
I just parachuted 2000 mgs of pregabalin powder. In two hours I'll see how fucked up I am. I have huge tolerance though

Why would you take that much? That is too high of a dose. You should bring it down alot. My sister use to get the 75 mg lyrica and then she got the 150mg, I use to snort them for the best effects I thought.. the most I ever took was like 4 of the 150s... they were fun while they lasted. I'd rather have my ocs though haha =D
 
I took 14 lyrica 150, and shared a quart of rum with a girl in the park.
I remember feeling like i was floating and skinny dipping in the kiddy pool at like 2pm on a wensday with her, then nothing else

what im told:
I walked to a mall
fell asleep against the wall
cop came to get me, i couldnt stand, and everytime i tried i fell down
i apparently asked the cop if he could just suck my dick instead of sending me to jail
and then i reached in my pocket to grab my cellphone while talking to him
he thought it was a gun
i got tazed


long story short the next thing i remember im in the drunk tank, only in my boxers, picking fights with the officers. and they wouldnt let me sleep, everytime i tried they'd stomp the floor by my head outside the cell


Never touched the shit since that day, fuuuuuck
 
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