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Gabapentinoids The Lyrica (Pregabalin) Mega Thread v 2.0

yubacity said:
That was the highest i went i had brought indian signuture pregabs for 50 p each had tousands of them i would wake in morning take 15 300 mg straight off then through the day take 4 more packets of 15 300 mg . I was getting off the heroin and it took that much to help because i have been using them since i first stopped heroin in 2018 .When i pissed in toilet it had a head on it like beer my joints hurt felt like i had water on the lungs and in morning i could hear water moving in body my eye lid had swelled with fluid rough time got of it with 6 month taper and diazepam
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I'm glad you got better man, that sounds like a horrible situation to be in. What I'm doing is alternating pregabalin and phenibut. So it's like this: pregabalin day, nothing day, phenibut day, nothing day, and repeat. Seems to preserve the pregabalin effecrs
 
plumbus-nine said:
How on earth can one abuse pregab for years? I was prescribed it twice, first time 300mg were like being drunken, first time 900 I got all this manic dissociative goodness and I am not manic by nature. But after some time of 600mg/d all the effects were gone for good. Up to 2g nothing, then a grand mal like seizure. You are lucky to survive 18 fucking grams...

But what might answer the OPs question is that pregabalin gets actively transported into the blood by a transporter in the gut, so taking it with a meal will change the absorption.
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I get that manic effect too. Apparently it signals some kind of latent bipolar issues
 
candidsurprise said:
I'm glad you got better man, that sounds like a horrible situation to be in. What I'm doing is alternating pregabalin and phenibut. So it's like this: pregabalin day, nothing day, phenibut day, nothing day, and repeat. Seems to preserve the pregabalin effecrs
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You are basicly doing what i am i goit phenibut aswell always leave a day or 2 between phenibut use it also has a nasty wd which pregablin can mask completely . I always leave 5 or 6 days for pregabs because im so scared of their wd today i smoked heroin and now snorting coke. It partty time this weekend with pals so crack heroin today tommorow and today phenibut on sunday pregab on Monday . Then nothing for 5 days . Now a 300 mg capsule of pregablin gets me leave gaps for pregabs to work also phenibut handy for pregab wd dont completely mask it but helps
 
I was one of the ones who got very easy withdrawals and had doubts believing the horror stories about pregabalin. After ten mild withdrawals or so in a 3 or 4 years period, I got very uncomfortable paws that seem to last forever. It is around 7 months from my last dose of pregabalin, the paws consist of probably a glutamate storm that makes me feel anxious and uncomfortable in general, tiredness, difficulty concentrating and bad sleep.

My common recreative dosage of pregabalin was 225mg+150mg, though I got up to 600mg+300mg at the peak of tolerance a couple of times. I used to do quick tappers every time I wanted to quit. I tried slow ones too and didn't experience much difference in the resulting mild withdrawal which no matter the slowness was unavoidable but mild and short-lived. The problem for me never was the withdrawal if not the paws that I have now.

I believe the problem is with the GABAergic system because any amount of alcohol or benzos brings back mild withdrawal for a few days (increased tiredness, even worse sleep, headache, tinnitus, bloated stomach, diarrhoea, sweating, depression and smelly farts). I have been as long as 3 months without a drink or benzo and after that, a double whisky brought back the withdrawal the next day. The alcohol didn't seem to kick either giving an extremely mild effect with no tolerance at all, this reduced effect from alcohol started before and it has to be related to my abuse of pregabalin. Never had any withdrawal of benzos or alcohol before and I abused them very very rarely. Anyone has found this is happening to them? Never heard of anyone in my internet dips explaining that paradoxical relation between alcohol and pregabalin paws and that worries me. Any advice on treatment that anyone has tried? I do exercise and eat well and all. How long do you think I should be away from any gabaergic before I can be in the clear.

Interestingly even very weak things with some GABA activity like bacopa monnieri or ashwagandha bring back the withdrawal symptoms too. They seemed to help in the beginning but it was just postponing the unavoidable.

Quite a shame because I loved pregabalin, which put me in my best mood and it is probably my favourite drug for abuse, but it seems the price got too high for me.
 
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Above 450mg preg became toxic for your body, you we’re taking 600mg as a single dose, may be that’s the issue. When I’m on preg run for couple of weeks sometimes months I never take more than 300mg in single dose and I’m taking 1-0-1. When I’m on lower doses mostly 150mg I take 1-1-1
 
opiofr3k said:
Above 450mg preg became toxic for your body, you we’re taking 600mg as a single dose, may be that’s the issue. When I’m on preg run for couple of weeks sometimes months I never take more than 300mg in single dose and I’m taking 1-0-1. When I’m on lower doses mostly 150mg I take 1-1-1
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I very rarely took 600mg in a single dose. Just in the beginning when I was doing it very often and got quite a tolerance and build it slowly up there. The problems and paws came to in the tenth or so withdrawal much later when I was not taking such high doses anymore as I wasn't taking it many days in a row anymore as I found it to be a waste of time with the rampant tolerance, and with experience I found 225mg to be the sweet spot for me. I blame it on the number of withdrawals more than the few times I took too high of a dose. Not saying high doses are innocuous and don't cause harm, they sure do to some extent. Pregabalin has been shown to be extremely variable in different individuals in effect, effectiveness and harm.
But well, I am looking for solutions and related experiences and I know very well my use of pregabalin was far from ideal (it was abuse really).
 
Good luck! I hope you will find a solution and you will recover fully! Try to do extended morphology test, urine etc. I’m doing regularly just to be sure if my body is alright. Maybe there is something else that cause that and preg was just helping you to not feel any uncomfortable things you have.
 
opiofr3k said:
Good luck! I hope you will find a solution and you will recover fully! Try to do extended morphology test, urine etc. I’m doing regularly just to be sure if my body is alright. Maybe there is something else that cause that and preg was just helping you to not feel any uncomfortable things you have.
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Thanks. I already did. Everything is normal besides some monocytosis. The doctor said it was because I had been ill recently. I haven't, but really I didn't feel like explaining to him my life and I don't have much trust in doctors with these kinds of issues, normally they know close to nothing. If I haven't found the right paper I doubt very much they are going to find it. Sad to have to trust a drugs forum before a doctor, but it is the reality in which we live with those matters.
 
I took 600mg at about 2pm. It's now 9pm almost and I feel like I've plateaud.
I realise I have to be careful with this drug as I've felt their withdrawal from stupid high doses back in my 20s.
This drug gives me so much motivation. I can't help doing useful stuff, I can't walk past a sink and see dirty dishes in there, I frantically clean them; I'll tidy the house, do laundry, feeling great all the time.

I've managed to resist taking any more as I simply do not need it, and I know from experience I'll be wonky as fuck all day tomorrow if I take another 300mg capsule.
 
Used to take 300mg for sleep but it stopped working now I wake up early....so sometimes I take 1,200mg but even that sometimes doesn't work
 
Take this shit like it was prescribed from doc.Never ever get close to max.recommend dose from 600mg daily,which is huge.If you get something- 100-200mg daily max. and it helps you ok,but no more,than a month.Advice from old dog.Be very cautious with lyrica people.It can be hell or it can be help for somebody
 
Nas47 said:
Take this shit like it was prescribed from doc.Never ever get close to max.recommend dose from 600mg daily,which is huge.If you get something- 100-200mg daily max. and it helps you ok,but no more,than a month.Advice from old dog.Be very cautious with lyrica people.It can be hell or it can be help for somebody
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I know.....been on it for years. Higher doses like 1200mg 1800mg it just makes me feel drunk
 
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