This is a shit thread basically so ill try and interject some interesting shit in addition to solving your question there.
OK guys, heres your answer like min said, some chemicals you can eat SHITLOADS OF by any route and not get shit, but then you have the fact that this chemical may not be active in the places it gets into when you take it, and when the body releases it , it occurs such that it gets into the place it is effective.
PERFECT example, serotonin does NO good when you take it snorted, swallowed or injected, BUT, this is because it doesnt cross the blood brain barrier, what we do have is mdma which is almost EXACLTLY what would happen if you could get pure serotonin directly into the brain, and ive pondered what would happen having a direct infusion into the brain many times but its far fetched to say the least.
Also, the body can change itself in certain times such that one chemical is then active when it wasnt before, such like the codeine-morphine metabolism, without cytochrome CYP 2d6 you wouldnt feel shit from codeine, then if you had SHITLOADS of it, you might well overdose from a normal dose of codeine, perfect example again.
PEA isnt nearly as reinforcing as endorphins, this is beacause pea may cause a nice rush but this is just norepinephrine release, not very directly connected. When endorphins attach to receptors, you DIRECTLY get reinforcing effects and other positive results, you could use endorphins like morphine as an antidepressant way moreso than you could any stim no matter what.
Likewise, natural endorphins are essential to feeling ok, not those stupid fucking serotonin reuptake inhibitors, simply because you probably have enough serotonin already and that isnt the problem, its more related to endorphins and therefor any antidepressant you hope to actually fix the PROBLEM must be endorphin based.
Therefor for example, addicts are not just using drugs, they are maintaining there emotional health much more effectively than any other route, so back off on the addict/junkie demeaning, theyre doing precisely what they need
and truthfully, an opiate addict who has enough opiates would be in a better emotional situation than ANYONE using any other antidepressant, so the shit about ruining there life is bullshit as long as they have enough, most people would also be in the same situation if there endorphin system dropped off like happens when an addict is prevented from using opiates.
I have been looking into how you could make your natural endorphins more effective much like an ssri makes serotonin more effective, an SERI basically, this research could provide the following, a cure for opiate addiction that WORKS PERFECTLY and allows your natural opiates to maintain you, a REAL antidepressant that would literally let you take back your life, a pain preventer that would higher your tollerance for pain, etc... anyone who has anything to contribute to my research contact me.
In the mean time, i highly reccomend anyone whos depressed to look into opiate/endorphins rather than bullshit ssris, they may make you feel better but endorphins are DIRECT and probably the cause of your problem in the first place. Dont be detered by the fact you have to take them repeatedly, same with ssris you have to take them repeatedly to get an effect, endorphins work INSTANTLY though, ssris take WEEKS, another concern is that you might not have a steady source, and this is a major problem here in america that we deal with everyday, some people have doctors prescriptions like i do, some people buy shitloads at a time like i used to do, but my situation is more shifted toward needing pain relief than needing an antidepressant, which i do need to an extent.
As a parting note to this worthless, worthless thread, i want to offer a positive effect ive had from being on long term opiate therapy legally (and illicitly before that), i used to smoke weed CONSTANTLY to prevent depression and anxiety and that solved it perfectly, for a while i used weed and opiates together and i was good, i still smoke, but what happened is i unknowingly and unintentionallly stopped smoking so much, i used to smoke up to 10 times a day, now i hardly smoke once a day if that, i completely forget about it because i dont need it now, endorphin therapy solved the problem i had and therefor the cure i was using i didnt need anymore, i used to know when i needed weed and since the indicators i used to signal i needed weed werent happening like they used to, i just didnt use the weed and i noticed this after a few days, i thought whoa i dont need weed at these certain times? wow i must really have done something right.
And what i have now is somewhat of a better solution, my problem WAS endorphin based and i was covering it with cannabis which did help dont get me wrong, that shit was a life saver, but it wasnt directly reversing the problem like opiates have, and i actually feel more normal now than before, many of the side effects weed had are gone now as well however minor they were.
I want everyone to seriously consider rethinking there opinion on opiates even if you are dead set against those "damn addicts" because you may well find a cure inside a supposed curse.
ALSO , i am researching what foods contain the precursors to natural opiates, and this will be benificial to anyone involved in opiates for whatever reason, eating these foods would increase pain relief naturally and in combo with opiates, would help an addcit stop using opiates after they wean off, and would help normal people feel better and hopefully not need to take a pure drug such as an opiate or an SERI at all.
Thanks for your time, worthless thread, worthless thread
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~The Recreational Pharmacist
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FUCK plur
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AIM: TheTripDoctor