Sprout
Bluelight Crew
Vaped > all else. 
Fiendish as all Hell, but dayummmm that Dopamine rush.

Fiendish as all Hell, but dayummmm that Dopamine rush.

^ how do you vape it and how's the high compared to other ROAs? With an oil burner or foil?
I take mine via sublingual or oral when i'm using it for studying,
3-FPM is serotonergic so is worlds away from EPH.
Source: http://www.google.com/patents/US20130203752[TABLE="class: description-table"]
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[TD="class: description-td"]DA Rel: 43 nM[/TD]
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[TD="class: description-td"][/TD]
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[/TABLE]
[TABLE="class: description-table"]
[TR="class: description-tr"]
[TD="class: description-td"]5HT Rel: 2558 nM
NE Rel: 30 nM
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Hey All,
I seem to be reacting very differently to EPH since I started taking 75mg of Nortriptyline (a Tricyclic Antidepressant) I'm taking for neuropathic pain. It's started making me anxious/nervous/jittery/twitchy/panicy when used in relatively small doses (50mg insufflated), after several months use without any problems.
Do you think that these side effects could be caused by the fact that they both inhibit the re-uptake of Dopamine, as well as Norepinephrine to a lesser extent? Nortriptyline has the following binding affinity (ki[nM]):
Dopamine: 3100 ki[nM]
Serotonin: 16.5 ki[nM]
Norepinephrine: 4.37ki[nM]
I used to take 100mg intranasally with no problems, some times using it multiple times per day. But now, even one hit of 50mg is making me feel awful (during each of the last 3 times), and each time I used it, I soon reached for some Propranolol, Diazepam and Oxycodone to calm down and subdue the jitters.
If it's not the Nortriptyline causing it, I can't think why else this would just start happening to me? Does my Nortriptyline 'theory' stack up, or can somebody prove it wrong and rule it out? It's a shame it's happening, because a little dab of EPH every now and then was very useful in waking me up and getting me going for the day.
I do have some MPA, but I'm not willing to try that until I figure out what's going on.
I had that data, but for whatever reason: I had a decimal point in there... 25.58 nM.
Jesus Christ, I really need to stop using my phone for things like this!
... So was I right in thinking this is down to the neurotransmitter interactions and I should avoid its use until I come off of the Nortriptyline, which will probably be in January when I change from Nortriptyline and Oxycodone to just Methadone, via my pain management consultant?
As you seem to have a good grasp on plugging EPH, can you share with me some specifics? - I only bomb mixed in a shot glass with Gatorade and subsequently chased with a couple extra gulps to get that vile taste and the EPH down to my tummy - however, I'm not a timid bloke and want to try plugging for the benefits many have espoused on this site
Question 1: if your stim tolerance is at a 2-months-away-from-all-stims baseline level, what dose would you mix up for plugging - if your feeling really generous, the type of info that would answer this question even better, would be some basic guidelines as to the ratio of liquid (in ml) for said dose (I usually dose orally in the 35-50mg range) - if I feel ok handling, say, a 50mg dose, how much liquid should I inject with that dose?
Question 2: should a rectal dose be the same as I'd use orally? - I've read that the rectal roa comes with increased bioavailability, so I'm just curious and, in the interest of HR, don't want to overdo it
Question 3: I usually dissolve mine in a shot glass of Gatorade, then chase the foul first shot with a couple more gulps of Gatorade to wash the goodies out of my mouth and down to my tummy (works great, btw) - the question is: do you dissolve the rectal dose in plain water? - or would it be better/ok to use Gatorade or perhaps a sterile saline solution?
Question 4: do you mind going into detail as to your exact rectal injection procedure? - what type/size of syringe is used, what type (if any) of lubricant should used? - how far do you cram it in? - do you lay down on your belly? - or on your side? - or do it 'doggy style' with your bum in the air? - after injection, do you stay in the position for a bit to allow gravity to assist? - do I need to clench the cornhole afterwards and, if so, for how long after injection? - lastly, I read that a clean colon is important - how does one determine if he's cleaned out enough?
We're almost a month later and I'm still having trouble with my nose because of this stuff it's made a real mess of my sinuses it hurts my teeth every time I sneeze and get terribleI pain in my eyes as well