I am currently preparing some poppy pod extract (let's not call it tea just now) for rectal dosing.
My aim is to enjoy the morphine content better, and avoid the taste.
I've done a bit of reading about codeine bio-availability via this route. Codeine becomes morphine when processed by the liver. Apparently plugged codeine will get to the liver soon enough and undergo it's transition to morphine. People plug codeine and say it's fine.
However, I've also read that IV codeine is a terrible thing because it can cause pulmonary embolism. Additionally, IV codeine will cause massive histamine release before it's converted to morphine.
But IMing and plugging codeine are apparently OK. You can in fact get codeine suppositories. So my question isn't, is this OK, because it clealy is. It's WHY is it OK?
What is different about codeine entering the bloodstream via IM injection, or via absorption in the rectum, and codeine entering the bloodstream via IV injection? Obviously it gets there quicker, but once it's there why doesn't it cause those problems once it's there?
EDIT: I've just finished putting a simple extract of 1 giganteum pod up my chocolate highway. It amounted to about 50ml of liquid; as I use a 5ml syringe to plug, and as I'm not sure what rate rectal contents are absorbed, this has been spread over about 20 minutes, starting 15:35 and ending 17:55.
I'm pretty sure I can feel the first signs of opiate intoxication now. I don't expect this to be strong, I normally use three or four pods when I make tea, but the morphine BA should be about double, so I do expect to feel it.
EDIT2: Yes, starting to feel definitely opiated now. Fairly mild but that's to be expected given the low dose. Will be interesting to see where exactly this goes.
The sheer quantity of liquid involved is too much to scale up beyond one pod. I need to evaporate it off. Boiling destroys morphine so that's not an option. It might be feasible just to leave some in a shallow tray for a few days. But to be honest for that amount of faffing about I'd be tempted to just do a proper acid/base extraction, and rehydrate that for plugging.