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The Big & Dandy Nootropics Thread

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Hello BL and PD,

I went through this thread with a lot of interest. I have tried piracetam a year ago without much success. I didn't knew much about it, attack doses and nootropics in general. I have been reading a lot about it over the few last weeks and it's almost seem too beautiful to be true. I decided to order and give it a try again with those three this time: piracetam, hydergine and centrophenoxide. I was very lost at first and didn't knew where to begin with. Those three seems really interesting in terms of synergistic effects. I am a sciences student looking for higher performance.

Now I am wondering how I should start my regimen. Taking all of them at once doesn't seem like a good idea. Some people are definitely knowledgeable of nootropics here and am looking forward your advices. I was thinking about taking attack doses of 3000 mg piracetam for the 2-3 first days then 1000 mg each day while adding 2.25 mg hydergine to the regimen for 2-3 other days and after that 250 mg of centrophenoxide. How does it sounds? Thanks for the help!
 
Sounds good, just to be safe. Actually, what I would do is try each by itself for a day. The piracetam is exceedingly unlikely to produce any adverse reactions... I've never heard of it doing so. The hydergine may produce an adverse reaction, possibly, but this is also unlikely. The centrophenoxine, if anything, may make you feel stimulated.

So try each one by itself for 3 consecutive days, then combine the piracetam and hydergine (the meat of the combo). Then if it's fine, add the centro.

Many people find that green tea helps to make this combo more effective as well, due to the type of antioxidants it provides. And you will come to understand nootropics better if you take them and then utilize your mind. Just like physical exercise.
 
I'd go a bit slower and try Piracetam for one or two weeks, before adding Hydergine.
I've no experience with Centrophoxine.
 
Has anyone found the need to go for an attack dose of piracetam after a few days break from it?

Also, it has been said that combining acid and piracetam is a bad idea. Personally, I have found that with MDMA/piracetam combos too, because it makes the whole experience too lucid - it doesn't seem like I am rolling balls!

How about salvia/piracetam. I am curious to see if anyone has tried that, and whether the piracetam can help make sense of all the jarring information that salvia provides.
 
DemonSeed said:
Now I am wondering how I should start my regimen. Taking all of them at once doesn't seem like a good idea. Some people are definitely knowledgeable of nootropics here and am looking forward your advices. I was thinking about taking attack doses of 3000 mg piracetam for the 2-3 first days then 1000 mg each day while adding 2.25 mg hydergine to the regimen for 2-3 other days and after that 250 mg of centrophenoxide. How does it sounds? Thanks for the help!
Click to expand...

That sounds pretty good. You might want to be a bit careful with hydergine though, and perhaps take it alone for a little while, as Xorkoth suggested. Hydergine is a very potent substance and synergizes strongly with other drugs.

I think I posted this in another thread, but I just recently had a very bad experience taking 2C-E and hydergine at the same time. I was made dizzy, nauseous, delirious, trembly, basically all the symptoms of a high fever but without the temperature. :(

It seems that all is well if I avoid hydergine the days that I trip, or even if I take it in the morning and don't trip until the late afternoon. Or, perhaps, it wasn't a hydergine reaction at all -- I just blamed the hydergine because this was the first time I'd taken it right at the same time as 2C-E.

It pays to remember that these substances are all quite poorly understood and their interactions are unknown.
 
Thanks for your advice guys. I had thought about trying them on their own before mixing and I think it would be the safest and most intelligent way to start. I will definitely mix green tea with it. I started drinking tea every day since a few months. I just love tea and it's subtle effects. I talked about nootropics to a few friends who refuse to use drugs. It's funny to see how they also became enthusiast like me and want to try those particular compounds. But like you say BodhiSvaha33, we don't know much about most of those substances. We have to keep that in mind when using those, just like phenethylamines, tryptamines and other psychoactive research chemicals.
 
Last year for academic purposes I went on a heavy long-term nootropic regimen, it went a bit like this:
1-1.5 g piracetam qAM or BID PRN
250 mg choline qAM
240 mg Ginkgo Biloba Extract containing 20%(?) Ginkosides qAM
1 Vit-B Complex
Too much espresso

I did not respond well to the piracetam. WAY too much mental stimulation, I felt like my neurons were burning through so much glucose. I did experience some memory enhancement and, in the vein of Reimann Zeta's account, a sort of chemical thesaurus effect. I also found my general demeanor to tend towards nervousness, pronounced social anxiety juxtaposed with extreme extroversion, and annoying verbosity.

The chemical did have an amazing effect on the depth of cognition, every idea seemed Platonic in form, and the volume of thought production was downright overwhelming. I would say that this could be considered a "psychedelic" effect of piracetam, as I think back on it now, I can see a striking similarity between the cognitive effects of piracetam and the cognitive effects of certain psychedelics, 2C-E comes to mind, and LSD, but the similarity there is less so.

I'll explain: My thoughts come very rapidly and there is a web of interconnectedness, such that each idea generates a slew of of new somehow related ideas almost simultaneously; the information just rushes through so fast and there is so much connectedness that there is no time to encode anything and make use of it later. For me at least, piracetam is a most inefficient tool.

Xorkoth, your piracetam+2C-E report came to mind just now when I considered the 'information rush, interconnectedness, depth of perception' psychedelic effect of piracetam; is it possible that the 2C-E potentiated the piracetam, instead of the other way around? Or that it was a unique synergy rather than a potentiation of one or the other? I'd also be interested in your best estimate of your ability to recall the experiene in full, although since the report is stored electronically, you'd have the advantage there.

And I've always seen really high dose quotes for piracetam, but right around the time I stopped taking it for all of the detrimental sides, I would be 'off-baseline' at or below 150 mg.

Took a summer break from nootropics and this year I've been focusing on plant-based nootropics, my stack goes like this:
1-1.5 g chocamine qAM-->gets me strongly and smoothly dialed in, and it's got more antioxidants than green tea, plus the euphoria and increase in libido.
120 mg Ginkgo biloba w/ 20% ginkosides-->less is more with ginkgo
150 mg Bacopa monnieri BID-->a really excellent nootropic. Very calm, collected thoughts, and marked improvement in memory storage and recall.
Lots of Fish and Flax Oil
The occasional 500 mg of rhodiola, especially during weeks with multiple tests or papers due.
I recently cessated my 2-8 mg daily nicotine for general health purposes.
400 IU Vitamin E qD or BID
500 mg Vitamin C qD
200 mg ALA if I'm feeling toxic, like I ate too much tuna and need to chelate those heavy metals.
Also 2-300 mg GABA and ZMA nightly to promote healthy, restful sleep.

And since I have placed an emphasis on my overall health and stuck to nootropics of plant origin, my mind has generally been more orderly, I am of more even temperament, and cognitive tasks have become easier to manage. For a more quantitative measurement, I can compare my GPA in fall of 2006 (2.583) to my current GPA (3.833), though there are too many confounding variables to attribute this change to a substitution of nootropics. Maybe I was experiencing toxic effects from piracetam? Come to think of it, I was still using aspartame with alarming frequency during that period, excitotoxicity has certainly been attributed to it. Could the piracetam exacerbate excitotoxicity from an overdose of L-phenylalanine?

I definitely want to try Hydergine, I tried a flavored nootropic mixture powder that I believe contained hydergine and that at least was a most excellent formulation.

5-HTP is a shitty substance, it seems most here agree. I've always benefited from post-MDMA 5-HTP supplementation, but my attempts at 5-HTP alone for sleep promotion and mood lift have all resulted in an uncontrollable appetite for carbohydrates and fats and a feeling of being emotionally disconnected to the people around me.

I would be very much interested to know your thoughts, especially those on my adverse reaction to piracetam. And that really is all that I have got to say about that.
 
spacefacethebassace said:
Xorkoth, your piracetam+2C-E report came to mind just now when I considered the 'information rush, interconnectedness, depth of perception' psychedelic effect of piracetam; is it possible that the 2C-E potentiated the piracetam, instead of the other way around? Or that it was a unique synergy rather than a potentiation of one or the other? I'd also be interested in your best estimate of your ability to recall the experiene in full, although since the report is stored electronically, you'd have the advantage there.
Click to expand...

In retrospect from almost two years after the experience, I definitely think it was a case of the two synergizing together, but with the 2C-E dominating by far. It was literally just as if the piracetam allowed my brain to make all of the connections that the 2C-E was capable of facilitating. It was like a tremendously powerful and rapid information download... my senses blended into one "super-sense" (definitely a 2C-E trait) and I was experiencing what seemed to be the elevation out of the ordinary realms of 3-dimensions and a slice of the 4th, until I had risen above them, and was able to glimpse what I have long thought to be the 5th (or some other arbitrarily higher number) dimension, that of reality itself. I had the impression that this entirety of space-time that we inhabit is just one slice on the acis of reality itself, or perhaps probability is a better term for it. Just like we're stuck in one instance of time, we're also stuck in one stance of reality, but we're not stuck in one instance of "volume" (the third dimension). In this way, I became untethered from this slice of time and began to become untethered from this instance of probability. I could see the moments directly behind and ahead of me splayed out like an uncurling fractal, the nearest possibilities for my next action becoming evident to me.

However, this was so much information I began to feel very overloaded... it was extremely chaotic and reminds me of the force and noise you feel if you're standing right next to a train as it goes by at high speed. As my mind found all of these connections, I began to experience an increasing sense of synchroncity, as I could see how everything fit together regardless of time and space. As I became more and more connected, I then began waking up into our true state of consciousness, that of the universal consciousness or "god". This was the second time this happened but by far the most total and immersive. But my ego, of course began struggling, and the next little while was utterly horrifying, as I encountered the void for the first time.

Anyway, I suppose you know the rest. I just wanted to share some impressions on it from later on. It was definitely the effect of 2C-E, but it cut right through to the core, it seems because of the piracetam. Usually 2C-E leaves my ego pretty intact, but the piracetam seemed to allow it to totally demolish my ego with ease. I sometimes think about trying it again, but it was much rougher physically as well, and mostly I just don't know if I have the courage to experience that level of intensity again. But it was so incredibly psychedelic and full of clarity that it's tempting. it was the kind of trip that I can't possibly really conceive of outside of that mental context.
 
fizzacyst said:
There is some fear that taking 5-HTP, especially chronically causes some heart problems.
Click to expand...

So, take L-Tryptophan; which is naturally found in our diets: chocolate, oats, bananas, dried dates, milk, yogurt, cottage cheese, meat, eggs, fish, sesame, chickpeas, sunflower seeds, pumpkin seeds, spirulina, and peanuts
 
I have been taking 1g/day piracetam for about two weeks now, and can definitely feel a significant improvement in my cognitive and memory functions.

I also received Hydergine, and started on 2.25mg (half tab) with my piracetam regime yesterday and all I can say is that it's very strange!

I got a real buzz out of it. Sensory stimulation, and excitement, as if I just railed a fat line. Which was great, except that I was at work and the sensations made it difficult for me to concentrate! That slight mental buzz I get from piracetam also seem to increase five fold for most of the day.

Has anyone had any intense side effects from hydergine, It seems more suited as a recreational thing - I do not want to be spaced out at work.

Or could the piracetam/hydergine be potentiating the effects of Wellbutrin that I am taking?
 
^^ samadhi_smiles has reported that hydergine produces a strong effect and dilates his pupils. Personally, I get a balancing of emotions and a feeling of wellbeing from hydergine, as well as a significant enhancement of piracetam. It particularly seems to aid in my word recall when speaking.

However, I can imagine that the two could very well potentiate Wellbutrin.
 
In that case, should I half the dose of hydergine again and have 1.1mg instead? Or just try hydergine on its own for a few days before combining the two?

I am also looking at adding choline and alpha gpc back into the daily regime, I hope that's ok..
 
spacefacethebassace said:
Last year for academic purposes I went on a heavy long-term nootropic regimen, it went a bit like this:
1-1.5 g piracetam qAM or BID PRN
250 mg choline qAM
240 mg Ginkgo Biloba Extract containing 20%(?) Ginkosides qAM
1 Vit-B Complex
Too much espresso

I did not respond well to the piracetam. WAY too much mental stimulation, I felt like my neurons were burning through so much glucose.

I would be very much interested to know your thoughts, especially those on my adverse reaction to piracetam. And that really is all that I have got to say about that.
Click to expand...

The effects you describe are exactly what i got with piracetam back when i was taking that (just in combination with choline - nothing else) . After the attack dosage started to work I cut back to about 1 to 1.5 grams because this is what most people report taking. At first it seemed worthwhile but latter i started getting over stimulation where I felt hyper and the effects seemed counter productive. I even started to worry about appearing like i was on speed or something at work. This was even worse if i drank tea (which i like to do for the taste and the caffeine) as the piractam potentiated the effects of the caffeine.

Rather than cut out the piractam i just tried lowering the dosage. Nowerdays when i take the stuff i stick to about 400mg once daily first thing in the morning. The effects i get from this low dose are very noticable and worthwhile but mild enough not to get in the way. I love piracetam - piracetam and caffeine are two chemicals that i really feel enhance my cognitive ability and general productivity.
 
How does piracetam influence LSD?

Hi guys! I wanted to know how does LSD interact with piracetam? Does it enhance the experience? If so, what should be the proper timing? What's the proper ammount of piracetam i should take assuming that i take one hit of good acid

peace
 
I have taken LSD once since I started a daily regime of piracetam, and I didn't notice any major difference from previous acid trips. The nature of LSD is that it will completely overwhelm most other drugs, particularly piracetam, which has a subtle effect in the first place.

The only nootropic I'd be wary of combining LSD with is hydergine. I have had negative interactions between hydergine and 2C-E, though I have never taken it with LSD. Hydergine is an ergot derivative and structurally related to psychedelics.
 
^Woah man! That's like totally self referential. I clicked the link, read the thread, clicked the link and encountered infinity;)
 
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BodhiSvaha33 said:
I have taken LSD once since I started a daily regime of piracetam, and I didn't notice any major difference from previous acid trips. The nature of LSD is that it will completely overwhelm most other drugs, particularly piracetam, which has a subtle effect in the first place.

The only nootropic I'd be wary of combining LSD with is hydergine. I have had negative interactions between hydergine and 2C-E, though I have never taken it with LSD. Hydergine is an ergot derivative and structurally related to psychedelics.
Click to expand...

With the piracetam, did you take it right before or shortly before the LSD, or were you just taking it in the mornings and took the LSD hours later? I ask because piracetam does not seem to potentiate substances for too long... you have to take it an hour or two before, not several hours. Although being on daily nootropics does seem to slowly alter my experiences until I stop taking them... it makes them clearer-headed.

Anyway, I have not tried piracetam specifically with LSD, but some people report that it makes the LSD much stronger by dose. Someone even said 4 times stronger. But then, others reported not much or a negative interaction. Really, it's pretty dangerous to combine nootropics and psychedelics, in my opinion. We know so little about it, and I have personally experienced wild potentiation to a frightening degree (2C-E) as well as feeling like I had the flu instead of tripping (5-MeO-MiPT). It's just too unpredictable.
 
I've tried piracetam with LSD (within an hour, specifically to see if there was any potentiation) and found that it did indeed seem to increase the strength.

I wouldn't have said it was x 4 strength, though i didn't get the chance to take the same dose of the same acid at a latter date without piracetam so i am guessing here slightly. It felt more like 1.5 x or 2 x strength, though the potentiation wasn't applied to all the effects of the LSD equally so it felt different qualitatively as well.

To try and describe this difference, it felt more 'crystalline' somehow with more intense OEVs and CEVs. It also felt more mentally confusing and i was glad i was taking the dose at home in a calm environment. I was more aware of my brain in that way piracetam seems to cause, which was very interesting combined with the LSD because it felt like i was more aware of exactly what the drug was doing inside of my brain. It was a while ago now so I'm sorry I can't describe it better.

I didn't feel that the effects where dangerous or necessarily unpleasant but I would recommend anyone trying this be very careful and start low with their doses the first time they try it.
 
^^ I found it to make 2C-E's mental effects much more confusing as well. As I mentioned before, it seems to me that piracetam potentiates psychedelics primarily because it allows the mind to make better and faster connections, which helps the psychedelic to reach its potential easier.
 
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