In my--admittedly limited--experience, body weight and/or chemistry vastly affects the dosing of phenibut. I tend to be in line with most ranges I've seen, with >1g being a "recreational" dose and 5-600mg a noticeable anxiolytic-but-not-inebriating effect. I stick to the smaller dose for days with anticipated high-anxiety events, such as public speaking; ~1g for social lubrication or in combination with psychedelics; and 1.5-2g for "I wanna get drunk but not spend a ton of money and the next day in bed." My wife, on the other hand, goes from nothing at 250mg to mood lift at 400mg to two-or-three-drinks-in at 500mg! She's also 100 pounds (45kg) soaking wet.
I have yet to experience anything I would consider truly nootropic, however. (Other than, perhaps, better wisecracks?) That said, I don't take a daily regimen; it's more of a tool, or occasional toy. For clearer thinking and better memory recall I notice more effects from piracetam.
On that note, I'd like to ask: Has anyone else had better effects from higher-than-usual doses of piracetam? Most people seem to take <1g daily, with or without starting "attack" doses; I've found that I get nothing from that. When I first tried piracetam a few years ago, I took daily 700mg doses and never experienced any tangible benefit, so when my supply ran out I didn't bother ordering more. After reading more glowing reviews here and elsewhere recently I decided to try again, this time by starting with a high attack dose and tapering down to 800mg/day. This time, I definitely noticed some improved cognition--more of a clear-headed "sharpness"--on the first two days, but as the dose tapered down, so did the effects. Then I stumbled upon
this post. (Apologies if this has been posted before.) Now, 4.8g 2x daily seems a bit extreme to me (mostly because the bitterness quickly goes from barely there to palatable to *RETCH* as the dose increases, and 4.8g is way to much to cap up), but I decided to increase my daily dosage anyway and I would say for me the optimum minimum dosage is 2.4g/day with breakfast. Does this experience line up with anyone else? Perhaps a better question: Does the literature included in that post hold up to scrutiny? Here are the abstracts for reference, although they appear to be neatly copied--if
edited for emphasis--in the forum post:
1)
https://www.ncbi.nlm.nih.gov/pubmed/10555876
2)
https://www.ncbi.nlm.nih.gov/pubmed/8272204