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The Big & Dandy 'Nausea and Psychedelics' Thread

20mg is where 2C-I becomes worthwhile for me, its definitely my least favorite 2C so far, but has its uses.

If you are taking "150-250 milligrams on a regular dose." your 2C-I is either quite impure (which was a well known issue with a major vendor of 2C-I) or you should really give it a rest. :\

Besides the OJ tip above, taking NAC during the comedown can help with the dreaded 2C-I headache in my experience.
 
I usually eat a piece of fruit about 10 min before I eat 2Cs and an aspirin when I start coming down.
 
OxyContin Queen said:
You guys, i just wanna say, i have been doign 2c-i and other phenethylamines for over the past 5 years, i've tried all the 2c compounds available, as well as all the different dmt structures.

A phenethylamine that i have ALWAYS had a massive amount of stomache discomfort on was 2c-e, with 2c-e I would always puke, purging and then i would be high, and uncomfortable the rest of the duration of the trip.

2c-i is however incredibly easy to ingest without causing any nausea, if it is in the bulk powder form why not try wrapping it up in a piece of one-ply toilet paper and doing it parachute' style. Or if you want, go out to the health food store, and grab something like some vitamine suppliments in a cap that u can take apart, empty, refill and then ingest.

if you want, i can post a few trip reports from previous 2c-i trips of
mine. If you do 2c-i alot then you will quickly gain a tolerance for it. An example of my tolerance to the substance, well, a regular dose is 14-22 mg for a strong dose. i take 150-250 milligrams on a regular dose.
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150+mg of 2c-i, either its bs or its some weak ass shit
 
Or maybe he has some ridiculous tolerance.. Which would mean he has to be dosing on a daily basis I guess. That can't be good for you, plus abusing 2C-I in particular that way probably means lingering visuals lasting forever (not pleasant at all in practice!)
 
I can certainly imagine long-term daily or near-daily use of a 2C-X to eventually require a massive dose like that. Hell, I never did them nearly that often, for nowhere near 5 years, and at the worst 30-35mg of 2C-I or even that much of 2C-E before has been unfortunately weak. Even now, when I trip much less often and rarely use phenethylamines, lingering long-term tolerance causes me to need over 20mg of 2C-E for a decent trip whereas before 18mg shattered my world, or 25mg of 2C-I for a fun time, whereas before 16mg gave me strong visuals and a deep mindstate.

But yeah, OxycontinQueen, I do recommend calming down, as that much 2C-I could not be good for you. :\
 
^^Indeed. Rectal dosing is an awesome way to dose, like nasal for dose and just a little slower come-up, and oral-like in effects, without much actual total effect duration reduction. The only bad part of it is the fact that you have to put something in there... but just get over it... it's only a societal thing. It's certainly more comfortable than snorting something.
 
^ I couldn't give a rat's ass (no pun intended) about societal bias, I just find dosing that way a bit uncomfortable. It's well worth the advantages though, especially for 2C-x compounds.

And yes, I wouldn't dream of snorting 2C-x, I'd rather dose orally and puke a little than go through all that terrible burn (and probably puke anyway). Plugging definately is the way to go, especially given that this class of compounds is twice as potent via that route!
 
It's definitely a bit uncomfortable... just depends on how important its benefits are to you at any given time. I do notice that in general oral dosing provides the most profound experiences, although that's not always true... it just tends to be (for me). But oral dosing is also the most variable, unless you take care to fast for 24+ hours beforehand (which is not good for me - my metabolism is incredibly high and I have to eat a lot).
 
I used to get rEAL REAL REAL BAD gas on 2c-i, so bad my stomach would hurt on the sides of my body. so you can realive taht with activated charcoal.


also, drink lots of water and take ALOT of vitamines on the coem down, something about 2c-i gave me the absolute worst head ach Iv ever experienced numberous times when I went through a 2c-i fase (lack of LSD and uber abundentness of 2c-i)


though Iv triped 2c-i at music events/clubs and it actualy realy enjoyable if you get the good effects and right dose, 2c-i is sometimes psychedelic while other times its kinda stimulating euphoric.
 
Splitting the doses up would be one way of gradualizing the come-up and reducing chances of nausea. You could try taking an 11mg capsule, waiting an hour, then taking another. 22mg might be a slightly intense starting dose but not outrageous for someone who is reasonably well experienced with psychedelics and empathogens. I think you will find compared to most other 2Cs nausea is not much of an issue with 2C-I.

Best of luck on your experiment.
 
^ You will also reduce the peak plasma levels that way (ie trip at lower intensity than you would if you dropped both doses combined at the same time), also you will trip longer, which might not be a desired effect for 2C-I.

Personally I hate the come-up phase of 2C-I, even at lower doses, so I'd prefer to get it over with as quickly as possible. I've found plugging the most effective way for that (as well as greatly reducing the nausea and cutting the dose in half!)
 
^ absolutely true, peak levels will be affected... and yes, if you don't mind putting drugs up your butt I'm sure it works decently well. Can't say I've ever tried it...
 
I find that taking two Benadryl about 10 minutes before you dose is a great way to prevent some nausea. Benadryl works the same as dramamine, except is about 2x more powerful.

I used to throw up every time I did 2ce, but with the whole Benadryl thing, I don't throw up nearly as often.
 
TransitEternal said:
I also find 2c-i to be one of the most nauseating psychedelics that I have tried. It's the only one that has actually made me throw up during the come-up. But after that, it's smooth sailing.

I would agree with e1evene1even and try to ingest your dose over a 15-30 minute period, rather than just taking it all at once. Although I have never tried this myself, it makes sense to me that spreading it out like that would be easier on the stomach.

Of course, I could be totally wrong. But it's worth a try =D

Good luck!
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hmm. i guess this is a good example of how different people have different experiences. i have taken 2ci on many occations, anywhere from 10-50 mg at a time. and, i have never experienced any nausea. not even a little. i have thrown up from acid before, but never 2ci.
 
fastandbulbous said:
Yeah, that's a better excuse than mine for being a bit of a piggy, especially with chocolate! =D
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Yes, I must say I enjoy eating a lot! But in all seriousness, I eat a lot, and I feel hungry at least 5 times a day anyway. As an example, I'll eat 2 bowls of cereal in the morning with a protein shake (~30 grams of protein), then at work I'll snack on handfuls of cereal and a banana. Then for lunch, I'll be hungry and consume 4-6 pieces of toast with fresh-ground peanut butter spread on thick. And something else, like a bowl of bowl or some noodles or something. And hopefully, if possible, a bunch of blended-up fruit in a smoothie. Then I'll snack through the afternoon on things, maybe some relatively healthy crackers. Then dinner rolls around and I have some sort of full dinner. And then more snacking and dessert. And if I don't go to bed and stay up, I'll be fucking hungry enough for stomach rumbling and hunger pangs! I mean seriously, I must be some sort of freak... I'll eat a meal and feel stuffed, totally stuffed, uncomfortable-style, and an hour later my stomach is grumbling. Last time I went to the doctor, I had just eaten loads of food in the manner I described. it was 4:00pm by then, and I weighed 5 lbs less than the previous time, when I had been generally undereating! It just makes no sense, except that I have a really high metabolism, to the point where I'm always tapping my feet and moving something to some extent.

And despite this, I never gain ANY weight... I'm 6'1" and only 140-150 lbs... it varies by 10 pounds or so at any given time. The only thing that ever makes me feel full for any significant length of time is to stuff myself with beef, but then I also feel all lethargic and shitty.
 
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Gee, thanks for suggesting the possibility of said innuendo anyway!
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