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The Big & Dandy Methoxetamine Thread - The 3rd Dose

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twelvesevndi said:
also, seriously does no one else have their sense of hearing profoundly affected by this stuff? its like my earpiece has a high ratio compressor on it.
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+1. I find that music gets really strange on MXE: it becomes simultaneously tinny and distant, like I'm hearing it from a distant loudspeaker.
 
Im gonna give it a go orally tonight, intranasally last me a good long time, so i imagine orally would last be about 5-7 hours +afterglow.... What about the afterglow/ant-depresant effects like,would they last longer than intranasally?
 
I find it hard to get to sleep when i snort it, so im never gonna get to sleep when i eat it..
 
thenightwatch said:
wait wait wait did i read that right? this stuff is just as active orally as nasally?
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This says to me that there is an active oral metabolite which is more potent/longer acting. Tread carefully.

Any comments on the differences?
 
Kenaz said:
+1. I find that music gets really strange on MXE: it becomes simultaneously tinny and distant, like I'm hearing it from a distant loudspeaker.
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iv found that as well no matter if you spent hours setting it up to sound right it still sounds tinny . then the is the buzzing and ring in your head sound you get
 
Well as long as it is being rehashed again I found sublingual and oral to be roughly equipotent (with oral taking longer to come on) and intranasal lagging and more unpredictable. I.M. injection is significantly more potent (30% increase?) as is plugging (20% stronger). The duration is changed a bit depending on the ROA and they all have their benefits.
 
i've never tried mxe, but after reading these threads it sounds like it makes you pretty happy/manic.. does anyone have any experience taking it (small dose) during the onset of an lsd trip? im not sure if the two can mix safely (heard something about mxe messing around with serotonin receptors, and iirc lsd is similar to serotonin), but to me it sounds like it would be a bad trip preventative.. weed usually calms me down but sometimes paranoia gets the best of me and i freak out. any advice is appreciated ;D
 
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MXE will not ensure a good trip on LSD. Nothing will ensure a good trip, psychedelics are unpredictable. But I bet the synergy would be amazing. This stuff is like the LSD of dissociatives. I'm not sure if that makes sense, but it does to me right now while I'm tripping on it.

I also haven't felt any of the cardiac issues some people have reported so I'm tempted to combine this with MDMA.

It's great stuff. It hasn't had the depth that ketamine has had for me in the past but it makes up for it in the euphoria department. It definAtely feels good.
 
Transform said:
This says to me that there is an active oral metabolite which is more potent/longer acting. Tread carefully.

Any comments on the differences?
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you might be on to something... 20 mg oral...followed by another 25 mg oral 1.5 hrs later feels like 60 mg insufflated
 
Zildjian said:
does anyone have any experience taking it (small dose) during the onset of an lsd trip?
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I've done that with ketamine. If the dose is low, personally I think it might be a good idea as it helps ease into the trip nicely and the NMDA antagonist properties will mean less glutamate in the brain to cause stress during the trip.

The difference with MXE vs K is the stimulation combined with a drastic mood lift which could be a bit 'panicky' for some people.

It could be an interesting experiment, but not one I'd do myself without a benzo around.
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As for the perception of sound, I noticed the last time while on MXE my tinnitus was greatly improved. For a while I couldn't even notice it.

Since K is theorized to help with chronic pain by 're-booting' aberrant brain activity, I wonder if it could help with tinnitus too, (as that has to do with hair follicle cells which have been damaged so they constantly send a signal)?

------

As for the anti-depressant properties, last night after smoking some weed I felt this veil come from the back of my head over my frontal lobes filled with stress, pressure, negativity and pain. It was the depression that MXE had eliminated almost a week prior.

I thought to myself, 'I don't know how I lived with this and I don't want it back' and luckily after 20-30 minutes it went away again which was a relief.

This whole last week I've been like a new person and while the physical, pharmacological basis for my depression was eliminated by the MXE, I realize it will still take some to learn new positive habits and ways of interacting with people. The response I'm noticing from other people makes it easier though. :)

Tomorrow will be a very long day for me, filled with plenty of opportunities for stress, or to practice new behaviors.

Depending on how I feel over the next few days I'll probably medicate with a 25mg dose and I think eventually by having a more positive outlook I'll get to the point where I won't need MXE anymore.

Years ago I had 5 heavy ayahuasca trips in 8 days in the amazon and while that helped with my depression, MXE has worked better and I didn't need to go through hell for the results...
 
Oral is definetlyu a winner it hits like a train but its worth it...methox is active at a much lower dose when taken orally....WINNING
 
ROA is orally for me. Very nice experience and you only need a smalliash dose compared to snorting...
 
Transform said:
This says to me that there is an active oral metabolite which is more potent/longer acting. Tread carefully.
Click to expand...
I'm not sure why it's more potent orally than nasally, but rectal is more potent than oral reportedly (as is typically the case), so there's probably not an active metabolite created by first pass metabolism that's more potent than methoxetamine itself.

Post #52 of this thread:
So am I right in thinking that this order (least effect to most effective) is correct:

Snorting ~ (worst)
Oral
Sublingual
Rectal
IM
IV ~ (best)
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This ordering was confirmed on the same page, with the caveat that IV produced inferior qualitative effects -- compared to IM I'm guessing -- and resulted in no rush. I can say that IM is barely better than rectal, so rectal must be extremely bioavailable and fast absorbing (plus less prep work than IM). I've only tried IM, rectal and snorting. Snorting was definitely the most wasteful of the three.
 
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amanitadine said:
Well as long as it is being rehashed again I found sublingual and oral to be roughly equipotent (with oral taking longer to come on) and intranasal lagging and more unpredictable. I.M. injection is significantly more potent (30% increase?) as is plugging (20% stronger). The duration is changed a bit depending on the ROA and they all have their benefits.
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I must concur with this assessment, except for the plugging bit. Know nothing aboot this ROA8)
 
Delsyd said:
MXE will not ensure a good trip on LSD. Nothing will ensure a good trip, psychedelics are unpredictable. But I bet the synergy would be amazing. This stuff is like the LSD of dissociatives. I'm not sure if that makes sense, but it does to me right now while I'm tripping on it.

I also haven't felt any of the cardiac issues some people have reported so I'm tempted to combine this with MDMA.

It's great stuff. It hasn't had the depth that ketamine has had for me in the past but it makes up for it in the euphoria department. It definAtely feels good.
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I combined it with MDA (160mg of MDA and 65mg of MXE by i.m. injection 4 hours into the MDA) with great effect. It's an entirely different ballpark than say, ketamine after MDMA but it was pretty damn nice in its own unique way. I get incredibly "delirious" on the comedown from MDA and the MXE really shined here. . a very sloppy zen pudding state :D For what it's worth I find MDA to be much harder than MDMA on my heart (and everything else!) and I didn't get any worrying cardio effects from the combination, nor any of the faux serotonin syndrome stuff that gets tossed around here so liberally. But then again I don't get too stimulated from MXE. . .I can fall asleep 2-3hrs into a 70mg dose without much difficulty and I don't get any noticeable tachycardia from it at any dose.

And ditto on the lack of "depth" compared to ketamine. It serves a different purpose :)

Cheers
 
I probably say that oral was better than Sublingual, it was almost like an E , not in terms of effects but it was a nice come up, not to long really surprised at how fast it was i dropped then first noticed effects at about half an hour later.....im not going to use intranasal as a ROA anyomore, just oral...and the afterglow/ant-depressant effects lasted well into the next day, i can can still feel some of it now.....

And i would probably put this ROA (oral) above Sublingual, and both of them before intranasal...
 
Anyone tried mxe on a sunny day in the park or is it just a drug for darkness, shadows, music and night?

Low dose obviously because, you know, you don't want to look nuts in public. So, any good with nature, mescaline style?
 
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