When you say numb, do you mean not feeling it or feeling a painful numbness in those areas?
Only a slight loss of feeling and then a few odd not really pains, but weird quick sensations, in my wrist or elbow area.
Mind you, I've used a total of probably 3gs in the past 2.5 years. All spread out between a 1g purchase, a 3.5g purchase (shared between a ton of people), and then most recently another 1g purchase.
I hadn't experienced this ever before until this last go, previous to which I hadn't used MXE in over a year probably? I got the gram, along with 500mg of 3-meo-pcp, probably four months ago and hadn't had any issues with this until last saturday. I've used almost all my gram at this point except for maybe 75-125mg. Pretty regular dosing, but never going higher than probably 75mg in one day, and that was only once or twice that I even got near that high in dosage. So pretty regular use, very infrequent use of 3-meo-pcp, and then Saturday I take maybeee 10mg MXE and a few mg's of 3-meo-pcp, and then 2.5g's of shrooms a couple hours later. I noticed the numbness a couple hours into the shroom trip while cooking and not really being able to feel how hot the pan was until a couple seconds of touching it.
In terms of the actual numbness, it's actually 90% gone away by today. But it mostly manifested itself in the right three fingers of my right hand, so pinky, ring, and middle finger, only slightly in the pointer. I didn't even really notice it was still there until the day after the shrooms when I was showering, went to wash my ass, and my ass hairs (so much stimulation I guess to the nerves from all the hair?) really brought out the difference in sensation. Fast forward to yesterday and I buy some aspirin and start taking that, 325mg x 3 yesterday, and 325mg x 2 today, and now it's mostly gone. I would assume the aspirin helped, but then again it could just be that the mxe and/or 3-meo-pcp is now completely out of my system.
I can't be 100% sure it was MXE itself, as the day it manifested I also took a small amount of 3-meo-pcp, but I'm sure they would both cause the issue as they have relatively similar methods of action.
Also, I do take adderall medicinally, anywhere from 15-50mg a day. I found a post back in the 9th reiteration of this MXE Big & Dandy by another young individual taking adderall also who had numbness in his right hand/arm. I'm thinking it could be a blood pressure issue? Some interaction between the dissociatives and the adderall because aspirin helps with that? No clue.