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The Big & Dandy Methoxetamine / MXE Thread - Holey Shit no. 15

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I think I have finally reached my breaking point with this chemical. Any time I bring it out with me I end up doing too much because I redose, wanting to get higher even though I'm already really high. I definitely need a tolerance break. I brought 200mg with me last night thinking i wasn't going to redose from the capsule of 45mg I took, I only brought extra to give it to friends. Well this morning I woke up and there is less than 50mg left and I didn't give any out 8o

I did at the very least 150mg last night at a concert.... what was I thinking? I have no idea but I only remember going to the bathroom to redose two times so I must have done it without remembering, which scares me. Next time I'm only bringing the amount that won't make me regret bringing it.
 
Isn't 150mg not really that much? I mean... I have had dose recommendations of 100mg to get to the M-hole with no tolerance and I have a mild perma-tolerance to dissociatives because of all the DXM I used to do.
 
I feel like 150mg is a heck of a lot... I've never pushed past ~80mg, and even then, it was getting really manic and weird...
 
Hmm... maybe its just my high tolerance. I have excellent stuff, just a bitch of a tolerance. 76mg seemed like it could be pushed to 80-90mg even.
 
Isn't 150mg not really that much? I mean... I have had dose recommendations of 100mg to get to the M-hole with no tolerance and I have a mild perma-tolerance to dissociatives because of all the DXM I used to do.

^ If someone recommended 100mg without tolerance then the MXE in question was definitely of low quality. 50mg of high quality MXE will get you to the hole if you're new to dissociatives and the stuff is pure, 55-65mg if you're a bit more hard-headed. Even when I had quite a bit of a dissociative tolerance, 70-75mg usually got me there without question.

150mg is a lot of MXE.
 
Well 70-75mg gets me there... but it feels like it can go further... or does it not?

I honestly can't say because I used to use DXM daily and the first time I holed on ketamine took 200mg so I have a stupid tolerance to dissociatives but 76mg felt like there was something missing... Yet I know for a fact (this batch was lab tested) that I had 99.6% pure MXE and considering the "dump it on my tongue and swish water around to get the taste out" approach I took it was semi-sublingual.

I have to say though... the batch that was "cut with salt" I found the bag today and I'm going to try 76mg and see... because I swear it was stronger.

I think it really is a polymorph thing. This is white polymorph, the other was yellow. The yellow was more visual while the white I thought was stolen was so dissociative it wasn't even funny.

It could also be the alcohol that I've been drinking before each MXE experience although I've heard that alcohol is one of the few things that is a nice addition to MXE so... I'm not sure.
 
Alcohol and MXE combine fine but it can dull the dissociation. I find all kinds of things to be nice to combine with MXE, especially when you do the MXE first.
 
I think it really is a polymorph thing. This is white polymorph, the other was yellow. The yellow was more visual while the white I thought was stolen was so dissociative it wasn't even funny.

It could also be the alcohol that I've been drinking before each MXE experience although I've heard that alcohol is one of the few things that is a nice addition to MXE so... I'm not sure.
Orrrr, it could be that the white, Chinese, stolen, super dissociative, cut with salt batch, was done prior to the yellow so it only seemed better...?
I, too, have the yellow polymorph and like the yellow as well as I did the white...I think so anyway...I also had the white first, so it's hard to tell for sure.
 
Yeah the yellow is just fine. It's really light yellow anyway, mine is, almost more of a light beige. It has a few small crystals in it here and there but is mostly fine powder, but not flour-like powder, it's coarser than that.
 
I think it's fair to say we all got our yellow from the same place. That's not source discussion it's just a base fact that the yellow polymorph was with one company.

I'm quite fond of both batches but that white polymorph from China even being salty is definitely more dissociative while the yellow is an outright full-blown trip.

What is the estimated duration of a single oral dose of MXE? For some reason I thought it was four hours but it appears to be shorter than that.

As for the alcohol interference, I wasn't drunk before doing any of them... Well maybe this last time. But either way even after all these years I'm still really tolerant to dissociative drugs because of the DXM I did back circa 2000. It's insane to think that tolerance won't ever go away but I took a total abstinence period from all drugs but alcohol from early 2012 til now and it's obvious I still have a beast of a tolerance.
 
What's all this talk of polymorph.
I've only ever seen one site advertise it as such and the dude running the site seemed a bit coocky, his website is set up as some sort of religion and all the drugs, excuse me I mean sacraments, all have funky names.
Someone explain polymorph. As far as I know all MXE has been MXE hcl.
 
What's all this talk of polymorph.
I've only ever seen one site advertise it as such and the dude running the site seemed a bit coocky, his website is set up as some sort of religion and all the drugs, excuse me I mean sacraments, all have funky names.
Someone explain polymorph. As far as I know all MXE has been MXE hcl.

I thought it was BS too until I read this.

https://www.drugs-forum.com/forum/showthread.php?t=208035

And long time no talk Delsyd! Hope all is well!
 
I am doing well, hope you are MK777.
I read that link but it did t really answer my question. The most informative post there was
How are the "polymorphisms" which you describe different from stereoisomers? Several of your explanations appear circular. Salts (as opposed to polymers such as polystirex) do not usually change the pharmacodynamics of the associated chemical (the ionic bond is broken immediately upon immersion into an aqueous solution). Unless I am mistaken, the crystalline structure is no longer relevant upon ionic dissociation in an aqueous solution, where only stereochemistry is pharmacologically relevant: water molecules will coordinate with the chemical according to the partial positive or negative charges of the hydrogen or oxygen atoms, respectively.

And I am one who does find some differences in different batches of MXE. I've never been able to figure out why and am skeptical about polymorphism being the answer.

Anyone here with actual chemistry knowledge want to chime in?
 
I am doing well, hope you are MK777.
I read that link but it did t really answer my question. The most informative post there was

And I am one who does find some differences in different batches of MXE. I've never been able to figure out why and am skeptical about polymorphism being the answer.

Anyone here with actual chemistry knowledge want to chime in?

There is actually science behind it

http://onlinelibrary.wiley.com/doi/10.1002/jps.20930/pdf

It has been reported in the literature that
this drug crystallizes in different polymorphic
forms, hydrates, and solvates depending on the
crystallization solvents used.

It has been reported in the literature that
this drug crystallizes in different polymorphic
forms, hydrates, and solvates depending on the
crystallization solvents used.

Seems like it could be a legit argument, I've seen the NMR data for two different polymorphs and they're both pure but very different in effects.

But I have two different batches here... yellow polymorph and white polymorph... and the white is very much more of a dissociative while the yellow is an amazingly spiritual and euphoric experience.

The fact that the exact synthesis route was never publicly released is probably resulting in different pathways to get to the same end chemical, which is bringing about different forms.
 
What is the estimated duration of a single oral dose of MXE? For some reason I thought it was four hours but it appears to be shorter than that.

For me; hours 2-3 is the strongest part of the experience.

This first hour is mostly the come-up depending on how long it takes to kick in (sometimes I eat before dosing). t+0:30-1:00 is the start of the dissociate effects, t+1:30-3:00 is the strongest part of the hole if I dose that high, t+3-4 is the beginning of the come-down though I'm able to still circle the hole if I really try. t+4-5 is a steep drop off in effects. t+6 is nearly baseline but I usually don't feel 100% until I sleep.

If I want a stronger experience I will re-dose at t+1:30 and t+2:30 which increases the effects and extends the time spent in the hole. I'll still come down around t+6-7 if I don't delay re-dosing too long.

I prefer MXE orally now but if I were going for a "I wanna hole and be floored like never before" experience I would plug it. It's a different beast plugged since it pretty much whacks you over the head with a mallet at t+0:15.
 
For me; hours 2-3 is the strongest part of the experience.

This first hour is mostly the come-up depending on how long it takes to kick in (sometimes I eat before dosing). t+0:30-1:00 is the start of the dissociate effects, t+1:30-3:00 is the strongest part of the hole if I dose that high, t+3-4 is the beginning of the come-down though I'm able to still circle the hole if I really try. t+4-5 is a steep drop off in effects. t+6 is nearly baseline but I usually don't feel 100% until I sleep.

If I want a stronger experience I will re-dose at t+1:30 and t+2:30 which increases the effects and extends the time spent in the hole. I'll still come down around t+6-7 if I don't delay re-dosing too long.

I prefer MXE orally now but if I were going for a "I wanna hole and be floored like never before" experience I would plug it. It's a different beast plugged since it pretty much whacks you over the head with a mallet at t+0:15.

Well it takes 200mg of K to hole me... and I have had I don't know how much DXM, 1200mg?, before I went to the dextroverse for real... I'm a stubborn bull.

Just took 80mg of the Chinese white... something told me to grab 80mg before I grab 25-50g from them... to see if their salt cut is acceptable. I'd estimate it to be around 10%... But its 5AM... so let's see how long it lasts... because the yellow is like someone mixed MXE with a mild tryptamine and sold it... even though I trust them completely... I'm looking at an hour and a half peak at the most... I seem to think that this one lasts longer but now I have a log...

Its sublingual... already hitting... and its been 2 minutes... it is going through my tongue, I feel it... so... maybe that changes everything... I just licked my tongue around until the salt was gone and my tongue is now numb... maybe I should sip something? I don't know... but I'm already high and its been almost 5 minutes on the dot.

Umm.. wow... my mouse arrow is gone... and its a trackpad... and 6 minutes in....

Wow you guys wouldn't understand what it took to get my cursor back... I started to reboot... then it wouldn't let me... then it crashed to Windows Help and now I have an icon... 7 minutes now... god this is gonna be a morning...
 
Can't believe the Gemini-20 picked up "4" but I just mixed 80mg with 4mg of 4-HO-MET...

I'll have you know that my GemPro didn't notice anything until 10mg... and then was still off a lot... this was... 4mg. And its kicking in... and I think I need to go hide for a bit... because they were at the same time and we all know MXE and 4-HO-MET hit within 15 minutes to peak... well I took the 4-HO-MET like 8 minutes ago.
 
For me; hours 2-3 is the strongest part of the experience.

This first hour is mostly the come-up depending on how long it takes to kick in (sometimes I eat before dosing). t+0:30-1:00 is the start of the dissociate effects, t+1:30-3:00 is the strongest part of the hole if I dose that high, t+3-4 is the beginning of the come-down though I'm able to still circle the hole if I really try. t+4-5 is a steep drop off in effects. t+6 is nearly baseline but I usually don't feel 100% until I sleep.

If I want a stronger experience I will re-dose at t+1:30 and t+2:30 which increases the effects and extends the time spent in the hole. I'll still come down around t+6-7 if I don't delay re-dosing too long.

I prefer MXE orally now but if I were going for a "I wanna hole and be floored like never before" experience I would plug it. It's a different beast plugged since it pretty much whacks you over the head with a mallet at t+0:15.

Yeah rectal MXE is a beast, I only ever use that if I'm trying to hole, not if I'm being social (which is almost always how I use MXE because it's just so damn good with group experiences). I prefer oral overall for sure, it's infinitely better than nasal or smoked for sure. Actually smoked MXE is like a different drug, fun, but shallow. It feels really good though, but you use SO much more, and it only lasts an hour.
 
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