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Lysergamides The Big & Dandy LSZ Thread

THE_REAL_OBLIVION said:
wow! much veil! such mystery!

The same applies to LSD still since the Pickard (be thankful, he invented that LSZ skinner wasn't happy with), never much if any busts of large quantities of LSD since then. I remember one guy in my province got caught with beautiful artsy blotter in the quantity of 1000+ around 2004 but that was it. I don't follow the drug busts thread anymore, if it even exists still.
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Skinner wasn't happy with Pickard's LSZ? I've never read that. do you have a source by chance?
 
What are the molecular differences between this and LSZ? What are the effects of the molecules that make it an analog?

Also... has anyone tried plugging tabs of this?
 
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rigadoog said:
What are the molecular differences between this and LSZ? What are the effects of the molecules that make it an analog?
Click to expand...

Indeed ^ what Thanatos said.

Which I explained a tiny bit in this post:
http://www.bluelight.org/vb/threads...LSZ-Thread?p=11672845&viewfull=1#post11672845

Also... has anyone tried plugging tabs of this?
Click to expand...

There should be no need. Lysergamides like these are readily absorbed fundally / you can take them sublingually or orally and it should be plenty potent - high bioavailability. Hey I've plugged stuff before and it is probably fine with this one, but if there is no advantage to it, there is no reason to do it unless you like corpus alienus i.e. sticking things up your bum in which case there are many more options like vaulting poles or certain kinds of tax return forms.
 
osla4n said:
Skinner wasn't happy with Pickard's LSZ? I've never read that. do you have a source by chance?
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The Rolling Stones article + testimony from Neurocunt girl. The Rolling Stones article is huge and old but still easy to find online. I think someone pasted it in a post over at the shroomery.

Here's what Neurorape Girl said in her Vice interview (from another site, it is verbatim) :

http://countyourculture.com/2011/12/01/non-lsd-ergoloids/

There were other novel substances as well. Leonard [Pickard] made a new LSD analog called “diazedine,” though I don’t know exactly what that was either.

Are you familiar with lysergic acid 2,4-dimethylazetidide?*

No, but they were calling this diazedine. It was also crazy, but nothing earth-shattering. Leonard [Pickard] gave it to Todd [Skinner] in a bottle of Everclear for testing, and we would dose a capful at a time. Apparently, diazedine failed to be doable on a large scale because the production costs were too high and the yields too low. Diazedine caused a lot of stress between Todd and Leonard, because they had high expectations for it as an LSD alternative.

*Lysergic acid 2,4-dimethylazetidide (aka LSZ) belongs to a very small group of serotonergic psychedelics that surpass LSD in potency. Aside from the fact that “diazedine” is a lexical clipping of dimethylazetidine (diazedine<dimethylazetidine), the first paper describing the chemistry and pharmacology of LSZ came out of a laboratory at Purdue University, where Leonard had previously studied under the renowned chemist David Nichols. Though the paper was published after Leonard’s arrest, it is still quite likely he was aware of the preliminary research. When I asked Dr. Nichols whether he thought Pickard may have produced LSZ, he replied, “Leonard knew of our work, of that I am certain.” Rumors of LSZ distributed on blotter paper (purportedly under the name λ) have circulated for years, though there are few confirmed reports of its existence. Of course, the name diazedine is ambiguous and could be referring to just about anything, but I would bet a kilo of benzotriazole-1-yl-oxy-tris-pyrrolidino-phosphonium hexafluorophosphate that LSZ and diazedine are one and the same.

From an interview of Krystal Cole, Life is a Cosmic Giggle on the Breath of the Universe, Vice Magazine.
 
Tried one blotter ( 150 ug ), was pleasantly suprised about it.
I liked the wohle trip , it feels just as pleasant as LSD ,
i was just smiling all day long .

But at this dosage ( at least for me ) are nearly zero visual at all ,
some minor movement in my vision if I look on walls and things like that.

I wanteds to try 2 blotters this weekend , should I wait another week to get my tolerance to zero ?
Or should it be okay , I dont want such a light trip this time.

Anyone of you guy tried LSZ with some MXE and MDMA ?
Im courious bout this combo.
 
I think you need a full week to get the tolerance down on lsz
i have mixed with nbome and liked the combination a lot.
 
Pay close attention to CEV's, they seem alot more prevelent that OEV's on LSz. 300ug should pick things up a fair bit though!
 
The isomers each appear to display very different binding properties. Discrimination studies showed the SS isomer to be most potent in animal models. This doesn't guarantee similar effects in humans. The ratio of 5ht1a and 5ht2a appears to change the subjective character of psychedelics in humans. The ratio in LSD is ~ 1 to 3 (1) and in SS-LSZ ~ 1 to 16 (1). SS-LSZ appears to show significant selectivity for 5ht1a over 5ht2a as compared to LSD.

I don't have direct experience with any LSZ isomer. My concern based on the data and experience is that the effects might greatly differ from LSD. Someone inexperienced might misinterpret the information available on LSZ, manage to obtain isometrically pure SS-LSZ , and distribute the chemical. The SS-LSZ would field test as LSD and could cause destructive consequences to the people who unwittingly consume the chemical thinking they received LSD.

The overall effects of psychedelics are dependent upon many variables. The only true test would be a human assessment. SS-LSZ might have very different effects than LSD. My goal is to emphasize the uncertainty and resultant risk with LSZ.

Reference:
1 http://www.erowid.org/archive/rhodium/pdf/azetidine-lsd.pdf

--------------------
http://www.shulginresearch.org
http://www.freeleonardpickard.org
http://www.maps.org
http://www.erowid.org
 
as far as I know all the LSZ currently on the market (or at least all that comes on the blotters with lsz printed on them) is the same isomer and does not test positive for lsd (back in september the police took a few blotters for me and tested them in their lab, they couldn't confirm it's 100% lsz because they didn't have a sample to compare, but it was definitely a lysergamide and not lsd... actually I think those were the first lsz blotters tested by the police anywhere in the eu)
 
black53 said:
as far as I know all the LSZ currently on the market (or at least all that comes on the blotters with lsz printed on them)
Click to expand...

That might be true. I don't know how someone could confirm every blotter with this design contained the same thing, even if they were the person laying the print. Could there be counterfeit prints circulating? There has been at least one counterfeit Hoffman print. (1) I have always presumed people laying blotter copy each others prints or use W.O.W. in order to obfuscate origin and mask distribution network even if they are laying LSD.

black53 said:
The same isomer and does not test positive for lsd (back in september the police took a few blotters for me and tested them in their lab, they couldn't confirm it's 100% lsz because they didn't have a sample to compare, but it was definitely a lysergamide and not lsd... actually I think those were the first lsz blotters tested by the police anywhere in the eu)
Click to expand...

I am unfamiliar with the Bunk Police. If they confirmed isometric purity I deduce they were using something more sophisticated than a reagent field test or black light. I couldn't find any published results on their website. Did they explain how they tested the sample?

References:
1 http://www.ecstasydata.org/results.php?start=0&search_field=all&s=bicycle

--------------------
http://www.shulginresearch.org
http://www.freeleonardpickard.org
http://www.maps.org
http://www.erowid.org
 
I meant the real police they had a warrant to search my apartment, found a few LSZ blotters, sent them to their lab to be tested, lab said it's a lysergamide, not lsd, and may well be lsz (couldn't confirm the last part 100% because they had no samples at the time).
 
Likely there is some. All psychedelics are cross-tolerant to some degree. However I would expect the cross-tolerance to not be too severe, as it would be, say, between AMT and MDMA (both releasers and entactogens).
 
had a very comfortable Monday night with 1/2 blotter (75 mics) LSZ - compared to recent tests with 25-i-nboh, it is much more awakened and less tweaky, superior overall like great bouillabaisse in moonlight compared to fish and chips in a tight drum.
 
As a general rule of thumb, drugs which share effects will exhibit cross-tolerance of those effects.
 
Big cross tolerance there must be between aMT and LSZ. I started with 1½ blotter earlier (6 hours ago??), now ate my last one I had. Not much had happen, last I tried it, it blew my mind away on 1 single blotter. Weird.
 
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