I think it would be beneficial depending on what you're looking for.
A bit earlier in this thread I posted about doing 450ug of ETH-LAD. I found that it got me to a place that felt very spiritual and deep (spirituality is something I actually try not to get into with these things), but was still extremely clear with no ego lost.
Over the weekend I had 300ug of good LSD which is my highest dose yet, and it didn't ever feel at all spiritual but I was feeling ego loss and trying to think of "me" was just a mess of fractals. It was to the point where I wanted to push through and lose myself but whenever it came down to it I got a bit scared and chose to stay in reality. I feel like I need to go to 400 or 500 of LSD to kick me over the edge and not give me a choice, but I was thinking that I could try something like 200ug LSD and 300ug ETH-LAD which may give me a closer feeling of what it's like being over that edge without being forced over it yet.
I don't think 50ug of 1P-LSD will do much at all if you "drop it later" after already taking a decent dose of ETH-LAD. Taking it with the ETH-LAD will increase the visuals a little bit and give you a bit more of the LSD headspace.
I'm considering mixing AL-LAD with ETH-LAD, and also doing a straight up 600ug ETH-LAD trip, although I fear the come up will be INTENSE