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The Big & Dandy ALD-52 Thread

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"""Acetylated organic molecules exhibit increased ability to cross the selectively permeable blood–brain barrier.[citation needed] Acetylation helps a given drug reach the brain more quickly, making the drug's effects more intense and increasing the effectiveness of a given dose.[citation needed] The acetyl group in acetylsalicylic acid (aspirin) enhances its effectiveness relative to the natural anti-inflammatant salicylic acid. In similar manner, acetylation converts the natural painkiller morphine into the far more potent heroin (diacetylmorphine""""

Okay so knowing this about the action of acetylization, why do you think that ald-52 isn't a more potent agonist than lsd-25? Isn't is sort of counterintuitive that it's considered a smoother less potent version of lsd?
 
maybe we are getting racemic compounds that act faster and are stronger but only 1/2 the effective measured dose (in pure dextro LSD) due to stereoisomer mix, only one version d-lsd is fully active, l-lsd is 10th the strength.
 
I'm pretty sure it's not racemic. LSD is amost always found as d-LSD, with maybe a tiny bit of the other isomers (LSD has 4 isomers) present as minor impurities. The guys making this know what they're doing. I think acetylation won't necessarily be as effective at increasing absorption for every molecule as it is for morphine. The absorption rate of the acetylated molecule depends on the properties of the parent molecule.
 
sean107 said:
Yeah since you have experience I'd go higher than 125ug if you feel up to it. I gave a very inexperienced friend 2 100ug tabs thinking him and his gf would be sharing the two hits, instead he took both but he still loved it.
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Sounds good to me! Yeah, I have plenty of experience and I would like a great, strong trip to bring me back into the lysergic realm. 250 ug sounds like it might be the perfect starting place. :)
 
Can't hurt :-) ^
I found it to left me, wanting to take it more often at that dose (250 to 300ug), than I normally do... that be, 4 times a year
Holding fast....

For a first time' er work your way up.. 250ug can be to much for certain personalities
 
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Is the jump from 300ug to 500ug overwhelming? I am thinking about it for therapeutic purposes, under the right set and setting of course.
 
Hyperflux said:
Is the jump from 300ug to 500ug overwhelming? I am thinking about it for therapeutic purposes, under the right set and setting of course.
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Have you taken high dose LSD before? Because it's pretty much identical at that dose. I find a little less comedown but that could just be cleaner synth.
 
Dosage with LSD is pretty difficult to evaluate. All I can say is that 1 tab of ald labeled 100µ was stronger than any LSD tab I took in my life. Not that I took just one tab very often becaus I don't like sub par trip, but 2 ald tabs of 100µ is equivalent to 3 LSD tabs for me.
 
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Hyperflux said:
Is the jump from 300ug to 500ug overwhelming? I am thinking about it for therapeutic purposes, under the right set and setting of course.
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I took my first wack at 375 the other day and man i gotta say this stuff is super easy going. The visuals increased but wgat really increased was the euphoria i got from the body load. Tbh it felt like i was rolling lots of eye flutters or wobbles. Any one expiernced with tryptamines should rember this bodyload. Felt similir to 4 ho met. Just bliss.
Even met a girl who has never had any lsd or psychedelics before and with a good trip sitter she took 7 hits over the course of 1 night for her first time tripping.( not my idea) but She gad zero problems navigating it. Seems like its kimda hard to freak out on this. I havnt seen anyone react negatively to it tbh. This stuff is smooth clean shit. No fried feeling next day no cramps nada. Just bliss ;-)
 
^
I'd go a little easy on the superlatives. Although it does feel quite easy on the body (yes, more than LSD), I found ALD-52 to be just as likely to induce paranoia, or at least intense or even unjustly harsh self-reflection, especially if taken in social settings. Last time I took it, a small and insignificant verbal blunder got me anxious for the remainder of the trip and pretty much ruined the experience.

I guess it depends on what kind of person you are, but although 75 µg was manageable in terms of staying within the boundaries of consensus reality, it made me realize that I shouldn't be taking these drugs socially at all because my self-image becomes completely distorted and I get far too vulnerable.
 
I agree. I think it's irresponsible to go around touting full blown psychedelics as 'easy to handle' and so nice that it's almost impossible to have a bad time on them. No matter how easy going comparatively, it's not following our policy of HR to be throwing around such heavy handed statements.
 
Hey i never said to follow the activities on my post. I was mearly stating what happened. I wasnt even there if i was i wouldnt have ever recomened such i high dose. No where in my post do i recomend for anyone to take such high doses.
All i was trying to say for me 375 was intense but still relatively easy going for myself. Thats because i have ate lsd and ald 52 more times than i can count. All i was saying is that people i know who have taken it has said its very clean feeling and for the most part perfect.
As far as the girl who took 7 hits over the course of the night she said that it was friendly in nature and she had no problems. And it was her boyfriends idea not mine
So where in my post do i recommend that first times take take insane doses?
I have been around along enough to know better than to recomend something like that. I did not know that your opinion counts as advice for others to follow. So give me a fucking break for christ sake.
 
Bigazznugz said:
Seems like its kimda hard to freak out on this. I havnt seen anyone react negatively to it tbh. This stuff is smooth clean shit. No fried feeling next day no cramps nada. Just bliss ;-)
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I never persecuted you like you seem to be reacting to Bigazz.

That being said, the statement as quoted above if read by a teenager or irresponsible drug user could lead to higher than needed doses or dosing in inadvisable environments leading to issues. Just because you have not explicitly said that there is nothing to worry about with this chemical, it's totally safe, etc. etc. does not mean you have not in some sense said it, ie. implied it. One must remember every action has consequences. In a setting like BL which is completely and totally based off of Harm Reduction principles we must be careful with what we put out there, staying aware at all times that our words could be read by absolutely anyone and perceived in a variety of ways.
 
I think I'll give 500ug ALD-52 a go then, but not without phenibut. I find that it really helps make the experience better without dulling it as benzos do.
 
Hyperflux said:
I think I'll give 500ug ALD-52 a go then, but not without phenibut. I find that it really helps make the experience better without dulling it as benzos do.
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I also often take Phenibut with lsd for the same reason than you but I didn't feel it was necessary with ald.
Not that I can't be irrational with ald but it's just less anxious and edgy.

Regarding taking lsd in social situation, I don't see the point to do social activities during a trip but I can't perfectly manage it 2 hours after peaking. It's like my brain was getting used to his new perception of reality.
 
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hopefully this account of using 50 mics (half blotter) 3 days after the last, is not too boring
the intoxication was equal to 1 beer except it extended 8 hours, and included psychedelic enhancement which beer does not.

the first 4 hours were shared experience doing normal things with my wife at the house, including the final inspection and payment of our house painter who really did a great job on the outside ( that included many mini-repairs that a painter usually does not).
then dinner and some GOTHAM, till I was alone awake.

the next 4 hours were quiet in bed with no screen or lights:
each position was lovely
eyes closed I was immersed in light jeweled arabesques and color patterns elusively reforming before perception gels, really there, yet easy to look away (ignore).
no mania, but some constant pressure to reach or connect with something essential
body sensation and mental activity merged into no-thought which is a kind of totality embrace-release thoughtless thought state.
this went on for some time, and eventually turned into sleep, and continues in echoes after waking.
 
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