The Big & Dandy 6-APB Thread (Part 5)

[Jesusgreen]

20 hours? Is this with redoses? Even with 250mg I was able to sleep after 12-13 hours. I've never noticed it taking longer than that, and I'm quite sensitive to the sleep-blocking effects of stimulants in general - e.g. unable to sleep for 12-14 hours after a single snorted 5mg dose of MDPV.

Going by EC50 values of closely related 6-APDB and 5-APDB, 6-APB should be (and certainly to me and many others feels) much more dopaminergic than MDMA. So I'm not sure why some people are saying they find it mellow and not very stimulating. OhZvir your description honestly sounds more like 5-APB to me. 5-APB is the more serotonergic of the two and very lacking in the dopamine department, and it lacks the overwhelmingly positive rushy push of 6-APB, meaning sometimes it can feel lethargic and not that great if you're not focusing on doing your best to enjoy the experience.

....Ah nevermind, just noticed you said 80mg - that's an underdose definitely and explains why you felt that way. For me the perfect dose is 150mg and I've not noticed any troubling side effects at this dose. There are others who find it amazing at as low as 100-125mg though, so I'd start there and work your way up.

 

[futuretastic]

I can generally sleep exactly 12 hours from the time I drop 6-apb. Never sooner, it's always the same time as I dropped when I finally doze off, but with the AM/PM flipped...

 

[MrPorter]

no redosing at all. Most effects are gone and I would feel fine the next day and I can get on with it as if I have had sleep, but there's not a chance my head will hit the pillow until the next night generally

 

[intelligentmind]

Has anyone combined mdma with 6-apb? if so, at what doses & what time frames, for example did you take the md first then 6 an hour later? & what was it like?thanks

 

[sonicteamaajm]

I had a bad trip on 6-apb the last time I took it with a friend (I've used it a few times before). I ordered it from the same supplier as before and all had been good in my previous trips. I did eye ball the amount we both took and I was sick upon the come up. I'm thinking I could have overdosed, but I'm not too sure. We both had a bad trip too, not just me. What do you guys think?

 

[intelligentmind]

Would taking Zyprexa only ONCE two days before taking 6 dull the experience? I don't need it just taking it for sleep

 

[Redbong]

I had a bad trip on 6-apb the last time I took it with a friend (I've used it a few times before). I ordered it from the same supplier as before and all had been good in my previous trips. I did eye ball the amount we both took and I was sick upon the come up. I'm thinking I could have overdosed, but I'm not too sure. We both had a bad trip too, not just me. What do you guys think?

I'm thinking overdose for sure. When I dose over 200 mg of 6-apb the nausea can get pretty bad at points. The trick to not over/under dosing is to buy a scale. You can get them cheap. You'll have better experiences and you'll be safe. Even if your mother doesn't know you do drugs, she'd appreciate it if you do it safely. Some of these drugs can kill you. Please buy a scale and use it. Your life may depend on it.

Something I noticed with 6-apb, it seems to expand as it ages. I have mine stored in 3 bags and an envelope at room temperature. When I first got it I could fit 200mg in a capsule easy. Now its a struggle to get 150mg in the same capsules. Absorbing water maybe? Maybe your old batch was just that, old. So, the new batch may have looked like the same dose, but been a lot more. Also, 5-apb seems a lot denser than 6-apb.

 

[Sepher]

Would taking Zyprexa only ONCE two days before taking 6 dull the experience? I don't need it just taking it for sleep

I'm no chemist and my understanding is limited so have come up with this reading around and seeing how Olanzapine's mechanism of action compares with Mirtazipine's which I'm more familiar with. Be nice if someone else could comment to check that I understand things correctly here, but . . .

Olanzapine's antagonism of 5HT2a/5HT2c where 6-APB is believed to bind and of dopamine D1/D2 receptors that come into play with dopamine release due to 6-APB's 5HT2a agonism with an average half life of ~30 hours? I would think it most certainly would diminish it to some extent, yes. Mirtazipine with a similar mechanism of action as an antagonist binding to 5HT2s can very effectively diminish the effects of psychedelics IME, I think through receptor blockade proper and / or tolerance caused by internalisation of receptors. Even after the Olanzipine's out of your system there's going to be some remaining tolerance caused by the internalisation.

 

[intelligentmind]

Ok, I thought i'd have to be taking it for a couple of days/weeks for it to block the effects

 

[Sepher]

5mg of Mirtzapine ( well below a therapeutic dose normally ) used as a one off for the first time in months as a sleep aid almost completely blocked 1.1mg of 25I-NBOMe a day later, barest threshold effects. Another attempt at it five days later produced very little improvement due to residual tolerance. Why am I banging on about Mirtazipine and NBOMes when you're asking about Olanzapine in the 6-APB thread i hear you cry, which is a good question, so let me answer it as best I can. Mechanism of action for both are I believe sufficiently similar for 5HT2s at least to make for a valid comparison. Make of the what you will. Others may take a different view. I guess you could still get effects depending what sort of doses of Olanzapine and 6-APB we're talking about, feel it would be difficult to say to what extent they'd be diminished.

 

[sonicteamaajm]

I'm thinking overdose for sure. When I dose over 200 mg of 6-apb the nausea can get pretty bad at points. The trick to not over/under dosing is to buy a scale. You can get them cheap. You'll have better experiences and you'll be safe. Even if your mother doesn't know you do drugs, she'd appreciate it if you do it safely. Some of these drugs can kill you. Please buy a scale and use it. Your life may depend on it.

Something I noticed with 6-apb, it seems to expand as it ages. I have mine stored in 3 bags and an envelope at room temperature. When I first got it I could fit 200mg in a capsule easy. Now its a struggle to get 150mg in the same capsules. Absorbing water maybe? Maybe your old batch was just that, old. So, the new batch may have looked like the same dose, but been a lot more. Also, 5-apb seems a lot denser than 6-apb.

Thanks for the reply! I'm usually careful with the does, but something obviously went wrong this time. Definitely going to get a scale, will be a lot better I'm sure! To be honest when I got that batch I thought it looked a tiny bit different, but nothing hugely significant. Then again maybe I was analyzing it too much.

Anyways, thanks for the help!

 

[Jesusgreen]

Has anyone else had some crazily potent 6-APB lately? Purchased 500mg last weekend, looked a little less based on my experience with the powder but I purchased it at the bar I was drinking at from a friend and didn't fancy the trek home for scales - split the entire amount between 6 people, one person didn't feel the effects (only had a tiny lick) but all 5 others rolled crazy hard, one said it was her most euphoric drug experience to date, another said it was one of his best, two others were real fucked up and me.. Well I was also on 1mg Buprenorphine so it was also my most euphoric experience to date.

What was odd though was that I've taken great quality 6-APB before up to 250mg and the only visuals I've gotten are a little wavyness around the edges of objects, some brightening, and some colourful cartoon CEVs - maybe a tiny blur.. But that night my vision was so blurred I was literally blind at some points and had to be dragged around half the night because I couldn't see properly..

Walking around the town after we came out looked like this:

Thankfully we stayed together as a group so I didn't get loss or stumble off into any ditches/alleys or anything. Went to a friends place and stayed there until I sobered up.

I noticed that my peak lasted a lot longer too but that might have been the bupe, I didn't have any sort of noticeable comedown or hangover other than feeling tired the next day (but I get that with bupe anyway) which was also unusual for me since 6-APB is usually harsher for me, and I'd dumbly even taken it a week before.

I can't see it having been another drug though it felt identical to 6-APB just far far stronger than normal. Was one of the best nights of my life

In hindsight there could have been more powder than we thought but unless my friend got the bags mixed up he said he weighed it up just before we came out to just over 500mg - and there was still a good 70-80mg or so left in the bag (still is) by the end of the night, which I'll save for maybe come January when my local re-opens :D

Weird because even 250mg didn't come close to that strength and for 5 people to roll that hard, another to take a dose, and there to still be 70-80mg left, from "just over 500mg", is crazy for me.

Guess either my friend made a mistake or the previous 6-APB on the market wasn't as pure as we thought. Either that or low doses oddly act stronger, since I did have that one roll where I took 80mg and rolled harder than 250mg. Iunno, all weird, but felt like posting it in case anyone else had similar experiences.

For reference the 6-APB was off-white rather than the usual tan I'm used to, which in the past has been a bad sign with 6-APB but in general with chemicals is normally a good thing, so maybe it is a sign the purity has gone up.

(ps don't jump into batch discussion with this, I'm commenting on the overall synthesis purity, since I've never tried any 6-APB that was this strong before, and asking if anyone else noticed a similarity - NOT for you to comment on individual batches and such please! )

 

[Delsyd]

Ive only ever had one batch of 6-apb and found it incredibly strong.
My first time trying it i did 100mg and rolled pretty good. Physically i felt like i was rolling very hard but i didnt get much of the emotional effects i love with MDMA and Methylone (and even mephedrone is more empathetic IME). I also didnt get visuals like people had been claiming to. So i felt like i should push the dose up the next time.
The second time i took 150mg. Again physically i rolled very hard. Too hard really as i vomited several times through out the night and into the next day. I also felt lingering effects all of the next day and couldnt do anything but drink water and take short naps. I wish i had a benzo or an opiate for that next day because i seriously felt like shit. But i was also pretty drunk when taking it this time so i feel that played a big role in making me feel ill and also not allowing to enjoy this experience. Some positives of this second experience were some nice visuals and mild head trip like you would get from a low dose of a 2c-x but combined with the sort of physical rushes you would get from a high dose of MDMA.
Next time i plan to take 150mg again but while sober and with a little food in my belly because i tend to vomit from drugs like these at high doses.
For comparison, i like to take 200-250mg of MDMA in one bomb and i found my 150mg 6-apb experience to be every bit as strong as that (but again i cant be sure because i was pretty drunk when i took it). It completely lacks any empathetic effects though IME, which is unfortunate because thats my favorite effect from empathogens, go figure .

 

[Jesusgreen]

I find the empathy to be quite high with 6-APB, but 5-APB and MDMA certainly beat it in that aspect. Not by a whole lot though, and at higher doses the differences aren't really noticeable, and it comes down to it more being a case of me wanting to get up and do things on 6-APB while on MDMA I'll be more happy to lay around just cuddling the whole time. I find it interesting you found Methylone more empathogenic though, I honestly got little empathy from Methylone (even in combo with 2C-B!) and to me it felt more like a cross between a strong DARI like MDPV or Cocaine - and MDMA, but far more rushy and far less lovey.

It's weird though, the time I took 250mg was from the place I'd trust most of all to get the stuff from, and this most recent dose was randomly given to me by a friend who got it EXTREMELY cheap, like ridiculously, to the point that I expected it not to work (can't mention specifics though, no price discussion!) and never told me where he got it from, so it was odd for it to be so much better by a mile.

I wondered if maybe this is the freebase form and the previous form was one of the salts? I'm not sure though, I think I remember hearing 6-APB freebase was an oil, but I might be remembering that wrong.

 

[Iridium]

Jesus would it be possible for you to perform a reagent test on the 6-apb you took? You could compare it to reagent test results you may have performed for other batches of 6-apb in the past or compare it to other reagent test results found around the web. Me for example I have a 6-apb that tested dark green/black with mecke (I forgot the result i got with marquis). I have yet to try it because according to other people's results those results are incorrect, and I'm concerned that I may be taking something cut with a more dangerous substance like PMA or something else. It would be interesting to know if the variable between these batches and the potency has to do with purity/cutting or even completely different substances possibly. The only other way to test this would be to get an analysis at the lab but that's a bit more troublesome..

 

[Sepher]

For reference the 6-APB was off-white rather than the usual tan I'm used to, which in the past has been a bad sign with 6-APB but in general with chemicals is normally a good thing, so maybe it is a sign the purity has gone up.

My latest supplies of the succinate form are only just off white / cream and I've noticed no difference in potency compared to the previous tan batches. Seems identical in every way JG. Could it be the much promised HCl at long last? It's apparently due if not here already? HCl is white isn't it? I dunno if the higher potency of HCL to succinate for 5-APB equally applies here? Anyone know?

I wondered if maybe this is the freebase form and the previous form was one of the salts? I'm not sure though, I think I remember hearing 6-APB freebase was an oil, but I might be remembering that wrong.

My understanding also is that 6-APB freebase is an oil at room temperature, available in succinate and HCl forms only for our purposes at least? Hence the pondering above. I know some UK vendors have been threatening HCl for the last few months, not sure if it is in fact yet available from them. Short of emailing them to ask I'm trying to find the answer to my own question above elsewhere also. Will come back if I get one JG.

 

[Delsyd]

I find the empathy to be quite high with 6-APB, but 5-APB and MDMA certainly beat it in that aspect. Not by a whole lot though, and at higher doses the differences aren't really noticeable, and it comes down to it more being a case of me wanting to get up and do things on 6-APB while on MDMA I'll be more happy to lay around just cuddling the whole time. I find it interesting you found Methylone more empathogenic though, I honestly got little empathy from Methylone (even in combo with 2C-B!) and to me it felt more like a cross between a strong DARI like MDPV or Cocaine - and MDMA, but far more rushy and far less lovey.
.

i havent had 5-apb yet but would like to try it if it has more empathy. I found 6-apb and MDMA similar in that they both monged me out. I couldnt imagine going out on 6-apb because of how strongly it affected me. i would prefer it at home at night with some music and friends and/or my gf.
I agree that methylone feels like cocaine and MDMA but i still feel strong empathogenic effects from it like i would from MDMA.

Is it possible you could have gotten 5-apb which is more potent by weight.

 

[intelligentmind]

5mg of Mirtzapine ( well below a therapeutic dose normally ) used as a one off for the first time in months as a sleep aid almost completely blocked 1.1mg of 25I-NBOMe a day later, barest threshold effects. Another attempt at it five days later produced very little improvement due to residual tolerance. Why am I banging on about Mirtazipine and NBOMes when you're asking about Olanzapine in the 6-APB thread i hear you cry, which is a good question, so let me answer it as best I can. Mechanism of action for both are I believe sufficiently similar for 5HT2s at least to make for a valid comparison. Make of the what you will. Others may take a different view. I guess you could still get effects depending what sort of doses of Olanzapine and 6-APB we're talking about, feel it would be difficult to say to what extent they'd be diminished.

Godamnit!! had something planned. Oh well i'll give it a miss for another month then

 

[Sepher]

^I'd hate you to take just my word for it, I could well be wrong? Depends how disappointed you'd be if I am in fact correct, doesn't it?

I find the empathy to be quite high with 6-APB, but 5-APB . . . certainly beat it in that aspect.

Interesting. Been discussing this elsewhere just today. 5 feels more straightforwardly stimmy to me, as if more dopaminergic. I like the serene and swimmy serotonin feeling I get from 6 more, feels more of a psyche than a stim to me and certainly more entactogenic / empathogenic than 5. This seems at odds with both others' experience, and the chemistry at play which others have led me believe suggests it should by the 6 which is the more domapinergic, 5 more serotonergic.

Theory: I wonder if the actual balance of neurotransmitters to receptors in a particular individual is what might account for differences in subjective effect, how up or down regulated one system is relative to the other for example? Any thoughts?

EDIT:

Jesus, I can take no credit for the quality of the research here, nor am I qualified to comment on its accuracy, but I trust the source to have done his sums correctly. Further to idle musings on whether you might have finally seen the much vaunted and alleged to be imminent HCl at long last:

6-APB freebase = 175.23 g/mol
6-APB HCl = 211.688 g/mol
6-APB Succinate = 293.315 g/mol

This means that 6-APB HCl is 82.77% 6-APB and 6-APB Succinate (the old stuff) it would be 59.74% 6-APB.

100mg of 6-APB base = 100mg 6-APB
100mg of 6-APB HCL = 82.77mg 6-APB & 17.23mg HCL
100mg of 6-APB Succinate = 59.74mg 6-APB & 40.26mg Butanedioic acid

Now if my maths is correct what that means is, very approximately, 6-APB HCl should be ~38% stronger weight for weight than the succinate. Would that be on a par with what you felt, or wrong ball park altogether?

 

[Si Dread]

Well, if the experience I am about to recount suggests there has been a recent increases in strength of 6-apb, it might explain a thing or two.

I have a history of stim/entactogen use after discovering Ecstacy in the early 90's. I've never really overdone it much so I've got a pretty clean slate & I'm small & I've always been ultra-sensitive to psyches, stims & entactogens.

I got some 5-apb & some 6-apb at the around the same time that the hcl version of 5-apb appeared. At some point over the last few months I performed an allergy test with a equal combination totalling 5mg. Obviously I had no effect. However, more recently I began what I expected to be a protracted attempt to find a comfy level for this material. I capped up 10mg of 6-apb & 5mg of 5-apb, ratio roughly as per Jesus instructions, taking into account the supposedly stronger 5-apb. I popped the cap & went to work as a cleaner, genuinely expecting no effects.

Effects surpriesed me. I felt no obvious come-up, which may have been awlward at work, but suddenly noticed I was feeling quite chilled, relaxed & confident. I was talkative with my client & felt more at ease doing so than I might usually. My skin felt warm, & sensitive such as with a mild dose of mdma. I felt vaguely spaced out & noticed a small degree of tracers & slight brightness to things generally. Despite working hard physically, I did not notice any obvious stimulation but honestly, who would've expected ANY effects at such low dosings. I'll be upping those doses next time, but not by much, I'm very interested in what I can get from loew doses. Though subtle for sure, they were certainly present, certainly pleasant, lasted some hours, & I'm quite pleased

Would the effects I've highlighted in red constitute pretty much what would be expected from a small dose of 5-apb/6-apb combo?